Neuroplasticity in old age: Some lessons from the enriched environment

Research and Practice in Alzheimer's Disease

Volumn 7, Issue , 2003, Pages 93-96

  Kempermann, G ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Adult neurogenesis; Hippocampus; Learning; Progenitor cell; Stem cell

Indexed keywords

ARTICLE; BRAIN; HIPPOCAMPUS; HUMAN; LEARNING; MORPHOLOGY; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; SENESCENCE; STEM CELL;

EID: 24744462528     PISSN: 12848360     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (9)

1. Kempermann G (2002) Why new neurons? Possible functions for adult hippocampal neurogenesis. J Neurosci 22:635-638.
2. Kempermann G, Gage FH (1999) Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal. Hippocampus 9:321-332.
3. Kempermann G, Gage FH (2002) Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance in the water maze task. Eur J Neurosci 16:129-136.
4. Kempermann G, Kuhn HG, Gage FH (1997) More hippocampal neurons in adult mice living in an enriched environment. Nature 386:493-495.
5. Kempermann G, Kuhn HG, Gage FH (1998) Experience-induced neurogenesis in the senescent dentate gyrus. J Neurosci 18:3206-3212.
6. Kempermann G, Gast D, Gage FH (2002) Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Ann Neurol 52:135-143.
7. Kuhn HG, Dickinson-Anson H, Gage FH (1996) Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 16:2027-2033.
8. Monje ML, Mizumatsu S, Fike JR, Palmer TD (2002) Irradiation induces neural precursor-cell dysfunction. Nat Med 8:955-962.
9. Van Praag H, Kempermann G, Gage FH (1999) Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 2:266-270.