Inclusion complexation of lorazepam with different cyclodextrins suitable for parenteral use

Drug Development and Industrial Pharmacy

Volumn 31, Issue 6, 2005, Pages 567-575

  Holvoet, Chantal ^a   Heyden, Yvan Vander ^a   Plaizier Vercammen, Jacqueline ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Cyclodextrins; Inclusion complexation; Lorazepam; Parenteral use; Phase solubility; Stability

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 7 BETA CYCLODEXTRIN SULFOBUTYL ETHER; BETA CYCLODEXTRIN SULFOBUTYL ETHER; CYCLODEXTRIN DERIVATIVE; GLUCOSE; HYDROXYPROPYL GAMMA CYCLODEXTRIN; LORAZEPAM; MALTOSYL BETA CYCLODEXTRIN; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; AUTOCLAVE; COMPLEX FORMATION; DILUTION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; FILTRATION; FREEZE DRYING; HEMOLYSIS; HUMAN; INJECTION PAIN; INJECTION SITE REACTION; LYOPHILISATE; PERFUSION; PHLEBITIS; PRECIPITATION;

ANIMALS; BETA-CYCLODEXTRINS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLODEXTRINS; DELAYED-ACTION PREPARATIONS; DRUG PACKAGING; DRUG STABILITY; EXCIPIENTS; GAMMA-CYCLODEXTRINS; HUMANS; HYDROGEN-ION CONCENTRATION; INJECTIONS, INTRAPERITONEAL; ISOTONIC SOLUTIONS; LORAZEPAM; MALTOSE; REPRODUCIBILITY OF RESULTS; SOLUBILITY; STERILIZATION;

EID: 24644515793     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040500214738     Document Type: Article

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