Spontaneous major bleeding in acquired factor X deficiency secondary to AL-amyloidosis

Haemophilia

Volumn 11, Issue 5, 2005, Pages 535-538

  Enjeti, Anoop K ^a   Walsh, M ^a   Seldon, M ^a  

^a NEWCASTLE MATER HOSPITAL   (Australia)

Author keywords

Acquired coagulopathy; Amyloidosis; Bleeding manifestations; Factor X deficiency; Spontaneous bleeding; Treatment of factor X deficiency

Indexed keywords

AMYLOID PROTEIN; ANTIBIOTIC AGENT; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 9; DEXAMETHASONE; MELPHALAN; PARAPROTEIN; PROTHROMBIN; PROTHROMBIN COMPLEX; PROTHROMBINEX;

ABDOMINAL DISTENSION; ABDOMINAL RADIOGRAPHY; ABDOMINAL SWELLING; ACUTE ABDOMEN; AGED; AMYLOIDOSIS; ARTICLE; BLOOD ANALYSIS; BLOOD CLOTTING FACTOR 10 DEFICIENCY; BONE MARROW BIOPSY; CASE REPORT; CLINICAL FEATURE; COLLAPSE; COMPUTER ASSISTED TOMOGRAPHY; ECHOCARDIOGRAPHY; EMERGENCY WARD; FEMALE; FOLLOW UP; GASTROINTESTINAL HEMORRHAGE; HEART LEFT VENTRICLE HYPERTROPHY; HEMATURIA; HUMAN; KIDNEY FAILURE; LABORATORY TEST; LIGHT CHAIN; MEDICAL EXAMINATION; PALLOR; PALPATION; PERICARDIAL EFFUSION; PNEUMONIA; PRIORITY JOURNAL; RETROPERITONEAL HEMORRHAGE; THORAX RADIOGRAPHY; URINALYSIS;

AGED; AGED, 80 AND OVER; AMYLOIDOSIS; BLOOD COAGULATION FACTORS; FACTOR X DEFICIENCY; FEMALE; HEMORRHAGE; HUMANS; RETROPERITONEAL SPACE;

EID: 24644483107     PISSN: 13518216     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2005.01125.x     Document Type: Article

References (15)

1. Falk RH, Comenzo RL, Skinner M. The systemic amyloidoses. N Engl J Med 1997; 337: 898-909.
2. Choufani EB, Sanchorawala V, Ernst T et al. Acquired factor X deficiency in patients with amyloid light-chain amyloidosis: incidence, bleeding manifestations, and response to high-dose chemotherapy. Blood 2001; 97: 1885-7.
3. Khan MF, Falk RH. Amyloidosis. Postgrad Med J 2001; 77: 686-93.
4. Mumford AD, O'Donnell J, Gillmore JD, Manning RA, Hawkins PN, Laffan M. Bleeding symptoms and coagulation abnormalities in 337 patients with AL-amyloidosis. Br J Haematol 2000; 110: 454-60.
5. Yood RA, Skinner M, Rubinow A, Talarico L, Cohen AS. Bleeding manifestations in 100 patients with amyloidosis. JAMA 1983; 249: 1322-4.
6. Tsukazaki K, Sukuwa M, Muratani Y et al. A case of retroperitoneal hemorrhage due to multiple myeloma complicated with factor X deficiency and amyloidosis. Nippon Naika Gakkai Zasshi 1991; 80: 757-8 (Mornaghi RA, Article in Japanese).
7. Furie B, Greene E, Furie BC. Syndrome of acquired factor X deficiency and systemic amyloidosis in vivo studies of the metabolic fate of factor X. N Engl J Med 1977; 297: 81-5.
8. McMahon C, Smith J, Goonan C, Byrne M, Smith OP. The role of primary prophylactic factor replacement therapy in children with severe factor X deficiency. Br J Haematol 2002; 119: 789-91.
9. Gertz MA, Merlini G, Treon SP. Amyloidosis and Waldenström's macroglobulinemia. Hematology (Am Soc Hematol Educ Program) 2004; 257-82.
10. Uprichard J, Perry DJ. Factor X deficiency. Blood Rev 2002; 16: 97-110.
11. Boggio L, Green D. Recombinant human factor VIIa in the management of amyloid-associated factor X deficiency. Br J Haematol 2001; 112: 1074-5.
12. Takabe K, Holman PR, Herbst KD, Glass CA, Bouvet M. Successful perioperative management of factor X deficiency associated with primary amyloidosis. J Gastrointest Surg 2004; 8: 358-62.
13. Guidelines Working Group of UK Myeloma Forum; British Committee for Standards in Haematology, British Society for Haematology. Guidelines on the diagnosis and management of AL amyloidosis. Br J Haematol 2004; 125: 681-700.
14. Greipp PR, Kyle RA, Bowie EJ. Factor-X deficiency in amyloidosis: a critical review. Am J Hematol 1981; 11: 443-50.
15. Rosenstein ED, Itzkowitz SH, Penziner AS, Cohen JI. Resolution of factor X deficiency in primary amyloidosis following splenectomy. Arch Intern Med 1983; 143: 597-9.