The role of primary prophylactic factor replacement therapy in children with severe factor X deficiency

British Journal of Haematology

Volumn 119, Issue 3, 2002, Pages 789-791

  McMahon, Corrina ^a   Smith, Judith ^a,b   Goonan, Collette ^a   Byrne, Mary ^b   Smith, Owen P ^a,b  

^a ADELAIDE AND MEATH HOSPITAL   (Ireland)

^b ST JAMES S HOSPITAL   (Ireland)

Author keywords

Central venous access devices; Factor X; Haemarthroses; Primary prophylaxis

Indexed keywords

BLOOD CLOTTING FACTOR 10;

ADOLESCENT; ARTHROPATHY; ARTICLE; BLOOD CLOTTING FACTOR 10 DEFICIENCY; BRAIN HEMORRHAGE; CASE REPORT; CHILD; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEMOPERITONEUM; HUMAN; IRELAND; MALE; PATHOGENESIS; PERINATAL PERIOD; PRIORITY JOURNAL; PROPHYLAXIS; QUALITY OF LIFE; SUBSTITUTION THERAPY; UMBILICAL CORD;

ADOLESCENT; BLOOD COAGULATION FACTORS; CATHETERS, INDWELLING; CHILD; FACTOR X DEFICIENCY; FEMALE; HEMORRHAGIC DISORDERS; HUMANS; MALE; PEDIGREE;

EID: 0036434925     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2002.03932.x     Document Type: Article

References (12)

1. Astermark, J., Petrini, P., Tengborn, L., Schulman, S., Ljung, R. & Berntorp, E. (1999) Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized. British Journal of Haematology, 105, 1109-1113.
2. De Sousa, C., Clark, T. & Bradshaw, A. (1988) Antenatally diagnosed subdural haemorrhage in congenital factor X deficiency. Archives of Disease in Childhood, 63, 1168-1174.
3. El Kalla, S. & Menon, N.S. (1993) Neonatal congenital factor X deficiency. American Journal of Pediatric Hematology and Oncology, 15, 135-138.
4. Kohler, M. (1999) Thrombogenicity of prothrombin complex concentrates. Thrombosis Research, 95, s13-s17.
5. Kouides, P.A. & Kulzer, L. (2001) Prophylactic treatment of severe factor X deficiency with prothrombin complex concentrate. Haemophilia, 7, 220-223.
6. Lechler, E. (1999) Use of prothrombin complex concentrates for prophylaxis and treatment of bleeding episodes in patients with hereditary deficiency of prothrombin, factor VII, factor X, protein C, protein S, or protein Z. Thrombosis Research, 95, s39-s50.
7. Machin, S.J., Winter, M.R., Davies, S.C. & Mackie, I.J. (1980) Factor X deficiency in the neonatal period. Archives of Disease in Childhood, 55, 406-408.
8. Nilsson, I.M., Berntorp, E., Loqvist, T. & Petterson, H. (1992) Twenty-five years experience of prophylactic treatment in severe haemophilia A and B. Journal of Internal Medicine, 232, 25-32.
9. Perry, D.J. (1997) Factor X and its deficiency states. Haemophilia, 3, 159-172.
10. Peyvandi, F., Mannucci, P.M., Lak, M., Abdoullahi, M., Zeinali, S., Sharifian, R. & Perry, D. (1998) Congenital factor X deficiency: Spectrum of bleeding symptoms in 32 Iranian patients. British Journal of Haematology, 102, 626-628.
11. Sandler, E. & Gross, S. (1992) Prevention of recurrent intracranial hemorrhage in a factor X-deficient infant. American Journal of Pediatric Hematology/Oncology, 14, 163-165.
12. Sumer, T., Ahmad, M., Sumer, N.K. & Al-Mouzan, M.I. (1986) Severe congenital factor X deficiency with intracranial haemorrhage. European Journal of Pediatrics, 145, 119-120.