메뉴 건너뛰기




Volumn 14, Issue 1, 2005, Pages 93-98

Expression of insulin-like growth factor-I receptor, estrogen receptor α, Bcl-2 and Bax proteins in human breast cancer

Author keywords

Bax; Bcl 2; Breast cancer; ER ; IGF IR

Indexed keywords

BAX PROTEIN, HUMAN; ESTROGEN RECEPTOR ALPHA; PROTEIN BAX; PROTEIN BCL 2; SOMATOMEDIN C RECEPTOR; TUMOR MARKER;

EID: 24644461751     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (44)
  • 2
    • 0029079651 scopus 로고
    • Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein
    • Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR and Olefsky JM: Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein. J Biol Chem 270: 19151-19157, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 19151-19157
    • Seely, B.L.1    Reichart, D.R.2    Staubs, P.A.3    Jhun, B.H.4    Hsu, D.5    Maegawa, H.6    Milarski, K.L.7    Saltiel, A.R.8    Olefsky, J.M.9
  • 3
    • 0033838566 scopus 로고    scopus 로고
    • Function of the IGF-I receptor in breast cancer
    • Surmacz E: Function of the IGF-I receptor in breast cancer. J Mammary Gland Biol Neoplasia 5: 95-105, 2000.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 95-105
    • Surmacz, E.1
  • 4
    • 0346095212 scopus 로고    scopus 로고
    • Expression of the Insulin-like Growth Factor-I Receptor in Primary Breast Cancer and Lymph Node Metastases: Correlations with Estrogen Receptors α and beta
    • DOI 10.1055/s-2004-814152
    • Koda M, Sulkowski S, Garofalo C, Kanczuga-Koda L, Sulkowska M and Surmacz E: Expression of the insulin-like growth factor-I receptor in primary breast cancer and lymph node metastases: correlations with estrogen receptors α and β. Horm Metab Res 35: 794-801, 2003. (Pubitemid 38058185)
    • (2003) Hormone and Metabolic Research , vol.35 , Issue.11-12 , pp. 794-801
    • Koda, M.1    Sulkowski, S.2    Garofalo, C.3    Kanczuga-Koda, L.4    Sulkowska, M.5    Surmacz, E.6
  • 5
    • 0033305004 scopus 로고    scopus 로고
    • Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
    • Lee AV, Jackson JG, Gooch JL, Hilsenbeck SG, Coronado-Heinsohn E, Osborne CK and Yee D: Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol Endocrinol 13: 787-796, 1999. (Pubitemid 30645331)
    • (1999) Molecular Endocrinology , vol.13 , Issue.5 , pp. 787-796
    • Lee, A.V.1    Jackson, J.G.2    Gooch, J.L.3    Hilsenbeck, S.G.4    Coronado-Heinsohn, E.5    Osborne, C.K.6    Yee, D.7
  • 6
    • 1842833905 scopus 로고    scopus 로고
    • Functional role of α-actinin, Pl 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells
    • DOI 10.1242/jcs.00104
    • Guvakova MA, Adams JC and Boettiger D: Functional role of alpha-actinin, PI 3-kinase and MEK 1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells. J Cell Sci 115: 4149-4165, 2002. (Pubitemid 35446810)
    • (2002) Journal of Cell Science , vol.115 , Issue.21 , pp. 4149-4165
    • Guvakova, M.A.1    Adams, J.C.2    Bettiger, D.3
  • 7
    • 0347986568 scopus 로고    scopus 로고
    • Insulin-like Growth Factor I (IGF-I) Stimulates Proliferation but also Increases Caspase-3 Activity, Annexin-V Binding, and DNA-fragmentation in Human MG63 Osteosarcoma Cells: Co-activation of Pro- and Anti-apoptotic Pathways by IGF-I
    • DOI 10.1055/s-2004-814140
    • Raile K, Hille R, Laue S, Schulz A, Pfeifer G, Horn F and Kiess W: Insulin-like growth factor I (IGF-I) stimulates proliferation but also increases caspase-3 activity, annexin-V binding, and DNA-fragmentation in human MG63 osteosarcoma cells: co-activation of pro- and anti-apoptotic pathways by IGF-I. Horm Metab Res 35: 786-793, 2003. (Pubitemid 38058184)
    • (2003) Hormone and Metabolic Research , vol.35 , Issue.11-12 , pp. 786-793
    • Raile, K.1    Hille, R.2    Laue, S.3    Schulz, A.4    Pfeifer, G.5    Horn, F.6    Kiess, W.7
  • 8
    • 0346725864 scopus 로고    scopus 로고
    • Activation of Pro-apoptotic p38-MAPK Pathway in the Prostate Cancer Cell Line M12 Expressing a Truncated IGF-IR
    • DOI 10.1055/s-2004-814160
    • Wu J, Haugk K and Plymate SR: Activation of pro-apoptotic p38-MAPK pathway in the prostate cancer cell line M12 expressing a truncated IGF-IR. Horm Metab Res 35: 751-757, 2003. (Pubitemid 38058179)
    • (2003) Hormone and Metabolic Research , vol.35 , Issue.11-12 , pp. 751-757
    • Wu, J.1    Haugk, K.2    Plymate, S.R.3
  • 10
    • 0031031824 scopus 로고    scopus 로고
    • Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells
    • Lee AV, Weng CN, Jackson JG and Yee D: Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells. J Endocrinol 152: 39-47, 1997. (Pubitemid 27026386)
    • (1997) Journal of Endocrinology , vol.152 , Issue.1 , pp. 39-47
    • Lee, A.V.1    Weng, C.-N.2    Jackson, J.G.3    Yee, D.4
  • 12
    • 0028839154 scopus 로고
    • Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation
    • Surmacz E and Burgaud JL: Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation. Clin Cancer Res 1: 1429-1436, 1995.
    • (1995) Clin Cancer Res , vol.1 , pp. 1429-1436
    • Surmacz, E.1    Burgaud, J.L.2
  • 13
    • 0036137605 scopus 로고    scopus 로고
    • Linkage of rapid estrogen action to MAPK activation by ERα-Shc association and Shc pathway activation
    • DOI 10.1210/me.16.1.116
    • Song RX, McPherson RA, Adam L, Bao Y, Shupnik M, Kumar R and Santen RJ: Linkage of rapid estrogen action to MAPK activation by ERα-Shc association and Shc pathway activation. Mol Endocrinol 16: 116-127, 2002. (Pubitemid 34044502)
    • (2002) Molecular Endocrinology , vol.16 , Issue.1 , pp. 116-127
    • Song, R.X.-D.1    McPherson, R.A.2    Adam, L.3    Bao, Y.4    Shupnik, M.5    Kumar, R.6    Santen, R.J.7
  • 14
    • 0035881568 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor α (ERα) via interaction between ERα and PI3K
    • Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV and Cheng JQ: Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERα) via interaction between ERα and PI3K. Cancer Res 61: 5985-5991, 2001. (Pubitemid 32762525)
    • (2001) Cancer Research , vol.61 , Issue.16 , pp. 5985-5991
    • Sun, M.1    Paciga, J.E.2    Feldman, R.I.3    Yuan, Z.-Q.4    Coppola, D.5    You, Y.L.6    Shelley, S.A.7    Nicosia, S.V.8    Cheng, J.Q.9
  • 15
    • 0034320568 scopus 로고    scopus 로고
    • Mechanisms of apoptosis
    • Reed JC: Mechanisms of apoptosis. Am J Pathol 157: 1415-1430, 2000.
    • (2000) Am J Pathol , vol.157 , pp. 1415-1430
    • Reed, J.C.1
  • 16
    • 0033621962 scopus 로고    scopus 로고
    • 17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence
    • DOI 10.1128/MCB.20.8.2890-2901.2000
    • Perillo B, Sasso A, Abbondanza C and Palumbo G: 17β-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence. Mol Cell Biol 20: 2890-2901, 2000. (Pubitemid 30183508)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.8 , pp. 2890-2901
    • Perillo, B.1    Sasso, A.2    Abbondanza, C.3    Palumbo, G.4
  • 20
    • 70449185514 scopus 로고
    • Histological grading and prognosis in breast cancer
    • Bloom HJG and Richardson WW: Histological grading and prognosis in breast cancer. Br J Cancer 11: 359-377, 1957.
    • (1957) Br J Cancer , vol.11 , pp. 359-377
    • Bloom, H.J.G.1    Richardson, W.W.2
  • 21
    • 4644307704 scopus 로고    scopus 로고
    • Expression of ERα, ERβ and Ki-67 in primary tumors and lymph node metastases in breast cancer
    • Koda M, Sulkowski S, Kanczuga-Koda L, Surmacz E and Sulkowska M: Expression of ERα, ERβ and Ki-67 in primary tumors and lymph node metastases in breast cancer. Oncol Rep 11: 753-759, 2004.
    • (2004) Oncol Rep , vol.11 , pp. 753-759
    • Koda, M.1    Sulkowski, S.2    Kanczuga-Koda, L.3    Surmacz, E.4    Sulkowska, M.5
  • 23
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • DOI 10.1016/S0304-3835(03)00159-9
    • LeRoith D and Roberts CT Jr: The insulin-like growth factor system and cancer. Cancer Lett 195: 127-137, 2003. (Pubitemid 36588961)
    • (2003) Cancer Letters , vol.195 , Issue.2 , pp. 127-137
    • LeRoith, D.1    Roberts Jr., C.T.2
  • 27
    • 0030670432 scopus 로고    scopus 로고
    • The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue
    • DOI 10.1002/(SICI)1096-9896(199712)183:4<412::AID
    • Happerfield LC, Miles DW, Barnes DM, Thomsen LL, Smith P and Hanby A: The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue. J Pathol 183: 412-417, 1997. (Pubitemid 27509247)
    • (1997) Journal of Pathology , vol.183 , Issue.4 , pp. 412-417
    • Happerfield, L.C.1    Miles, D.W.2    Barnes, D.M.3    Thomsen, L.L.4    Smith, P.5    Hanby, A.M.6
  • 28
    • 0034693680 scopus 로고    scopus 로고
    • Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer
    • Schnarr B, Strunz K, Ohsam J, Benner A, Wacker J and Mayer D: Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer. Int J Cancer 89: 506-513, 2000.
    • (2000) Int J Cancer , vol.89 , pp. 506-513
    • Schnarr, B.1    Strunz, K.2    Ohsam, J.3    Benner, A.4    Wacker, J.5    Mayer, D.6
  • 30
    • 0028233617 scopus 로고
    • The prognostic value of insulin-like growth factor-I in breast cancer patients. Results of a follow-up study on 126 patients
    • DOI 10.1016/0959-8049(94)90247-X
    • Railo MJ, von Smitten K and Pekonen F: The prognostic value of insulin-like growth factor-I in breast cancer patients. Results of a follow-up study on 126 patients. Eur J Cancer 30: 307-311, 1994. (Pubitemid 24152469)
    • (1994) European Journal of Cancer Part A: General Topics , vol.30 , Issue.3 , pp. 307-311
    • Railo, M.J.1    Smitten, K.V.2    Pekonen, F.3
  • 31
    • 0031585866 scopus 로고    scopus 로고
    • Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote e-cadherin-mediated cell-cell adhesion in human breast cancer cells
    • DOI 10.1006/excr.1996.3457
    • Guvakova MA and Surmacz E: Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells. Exp Cell Res 231: 149-162, 1997. (Pubitemid 27187524)
    • (1997) Experimental Cell Research , vol.231 , Issue.1 , pp. 149-162
    • Guvakova, M.A.1    Surmacz, E.2
  • 32
    • 0033001742 scopus 로고    scopus 로고
    • Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line
    • DOI 10.1038/sj.bjc.6690112
    • Parisot JP, Hu XF, deLuise M and Zalcberg JR: Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line. Br J Cancer 79: 693-700, 1999. (Pubitemid 29082092)
    • (1999) British Journal of Cancer , vol.79 , Issue.5-6 , pp. 693-700
    • Parisot, J.P.1    Hu, X.F.2    DeLuise, M.3    Zalcberg, J.R.4
  • 33
    • 0031047044 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 inhibition of apoptosis is associated with increased expression of the bcl-xL gene product
    • DOI 10.1210/en.138.3.1355
    • Parrizas M and LeRoith D: Insulin-like growth factor-1 inhibition of apoptosis is associated with increased expression of the bcl-xL gene product. Endocrinology 138: 1355-1358, 1997. (Pubitemid 27089798)
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 1355-1358
    • Parrizas, M.1    Leroith, D.2
  • 34
    • 0033600722 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein
    • Pugazhenthi S, Miller E, Sable C, Young P, Heidenreich KA, Boxer LM and Reusch JE: Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein. J Biol Chem 274: 27529-27535, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 27529-27535
    • Pugazhenthi, S.1    Miller, E.2    Sable, C.3    Young, P.4    Heidenreich, K.A.5    Boxer, L.M.6    Reusch, J.E.7
  • 35
    • 0032494175 scopus 로고    scopus 로고
    • Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I
    • Wang L, Ma W, Markovich R, Chen JW and Wang PH: Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I. Circ Res 83: 516-522, 1998. (Pubitemid 28411053)
    • (1998) Circulation Research , vol.83 , Issue.5 , pp. 516-522
    • Wang, L.1    Ma, W.2    Markovich, R.3    Chen, J.-W.4    Wang, P.H.5
  • 36
    • 15044352178 scopus 로고    scopus 로고
    • Expression of the insulin-like growth factor-I receptor and proapoptotic Bax and Bak proteins in human colorectal cancer
    • DOI 10.1196/annals.1329.047
    • Koda M, Reszec J, Sulkowska M, Kanczuga-Koda L and Sulkowski S: Expression of the insulin-like growth factor-I receptor and proapoptotic bax and bak proteins in human colorectal cancer. Ann NY Acad Sci 1030: 377-383, 2004. (Pubitemid 40378936)
    • (2004) Annals of the New York Academy of Sciences , vol.1030 , pp. 377-383
    • Koda, M.1    Reszec, J.2    Sulkowska, M.3    Kanczuga-Koda, L.4    Sulkowski, S.5
  • 37
    • 84880442977 scopus 로고    scopus 로고
    • Expression of the insulin receptor substrate-1 in primary breast cancer and lymph node metastases
    • In press
    • Koda M, Sulkowska M, Kanczuga-Koda L and Sulkowski S: Expression of the insulin receptor substrate-1 in primary breast cancer and lymph node metastases. J Clin Pathol (In press).
    • J Clin Pathol
    • Koda, M.1    Sulkowska, M.2    Kanczuga-Koda, L.3    Sulkowski, S.4
  • 38
    • 0029045784 scopus 로고
    • Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma
    • Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius VM, Niskanen E, Nordling S and Reed JC: Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Res 55:4471-4478, 1995.
    • (1995) Cancer Res , vol.55 , pp. 4471-4478
    • Krajewski, S.1    Blomqvist, C.2    Franssila, K.3    Krajewska, M.4    Wasenius, V.M.5    Niskanen, E.6    Nordling, S.7    Reed, J.C.8
  • 41
    • 0034667977 scopus 로고    scopus 로고
    • Differential expression of Bax and Bcl-2 in the assessment of cellular dynamics in fine-needle samples of primary breast carcinomas
    • Maciorowski Z, Klijanienko J, Padoy E, Mosseri V, Dieras V, El-Naggar AK, Chevillard S and Vielh P: Differential expression of Bax and Bcl-2 in the assessment of cellular dynamics in fine-needle samples of primary breast carcinomas. Cytometry 42: 264-269, 2000.
    • (2000) Cytometry , vol.42 , pp. 264-269
    • Maciorowski, Z.1    Klijanienko, J.2    Padoy, E.3    Mosseri, V.4    Dieras, V.5    El-Naggar, A.K.6    Chevillard, S.7    Vielh, P.8
  • 42
    • 0037235786 scopus 로고    scopus 로고
    • Immunofluorometric study of Bcl-2 and Bax expression in clinical fresh tumor samples from breast cancer patients
    • Martinez-Arribas F, Nunez-Villar MJ, Lucas AR, Sanchez J, Tejerina A and Schneider J: Immunofluorometric study of Bcl-2 and Bax expression in clinical fresh tumor samples from breast cancer patients. Anticancer Res 23: 565-568, 2003. (Pubitemid 36358452)
    • (2003) Anticancer Research , vol.23 , Issue.1 B , pp. 565-568
    • Martinez-Arribas, F.1    Nunez-Villar, M.J.2    Lucas, A.R.3    Sanchez, J.4    Tejerina, A.5    Schneider, J.6
  • 43
    • 0032055936 scopus 로고    scopus 로고
    • bcl-2 and apoptosis in lymph node positive breast carcinoma
    • DOI 10.1002/(SICI)1097-0142(19980401)82:7<1296::AID
    • Berardo MD, Elledge RM, de Moor C, Clark GM, Osborne CK and Allred DC: bcl-2 and apoptosis in lymph node positive breast carcinoma. Cancer 82: 1296-1302, 1998. (Pubitemid 28155391)
    • (1998) Cancer , vol.82 , Issue.7 , pp. 1296-1302
    • Berardo, M.D.1    Elledge, R.M.2    De Moor, C.3    Clark, G.M.4    Osborne, C.K.5    Allred, D.C.6
  • 44
    • 0242624594 scopus 로고    scopus 로고
    • Growth factor receptors as therapeutic targets: Strategies to inhibit the insulin-like growth factor I receptor
    • Surmacz E: Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor. Oncogene 22: 6589-6597, 2003.
    • (2003) Oncogene , vol.22 , pp. 6589-6597
    • Surmacz, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.