Large-scale fermentation for the production of teicoplanin from a mutant of Actinoplanes teichomyceticus

Journal of Microbiology and Biotechnology

Volumn 15, Issue 4, 2005, Pages 787-791

  Lee, Jae Chan ^d   Min, Jung Won ^d   Park, Dong Jin ^d   Son, Kwang Hee ^d   Yoon, Ki Hong ^a   Park, Hae Ryong ^b   Park, Young Soo ^c   Kwon, Mu Gil ^c   Lee, Jung Min ^d   Kim, Chang Jin ^d  

^a Woosong University   (South Korea)

^b Kyungnam University   (South Korea)

^c Central Research Center   (South Korea)

^d Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Actinoplanes teichomyceticus; Fermentation; Mutagenesis; Mutation; Teicoplanin

Indexed keywords

CALCIUM CHLORIDE; GLUCOSE; MAGNESIUM SULFATE; MALTODEXTRIN; SODIUM CHLORIDE; TEICOPLANIN; WATER;

ACTINOBACTERIA; ACTINOPLANES TEICHOMYCETICUS; ARTICLE; BACTERIAL MUTATION; BACTERIAL STRAIN; BACTERIUM MUTANT; CONTROLLED STUDY; DRUG SYNTHESIS; EXPERIMENTAL DESIGN; FERMENTATION MEDIUM; NONHUMAN; SOYBEAN; WILD TYPE; YEAST;

ACTINOPLANES TEICHOMYCETICUS; GLYCINE MAX;

EID: 24644457682     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Ashwell, G. 1957. Colorimetric analysis of sugars, pp. 84-85. In S. P. Collowick and N. O. Kaplan (eds.), Methods in Enzymology, vol. 3. Academic Press, New York, U.S.A.
2. Choi, D. and K. Cho. 2004. Effect of carbon source consumption rate on lincomycin production from Streptomyces lincolnensis. J. Microbiol. Biotechnol. 14: 532-539.
3. Heydorn, A., S. J. Trine, and J. Nielsen. 1999. Growth and production kinetics of a teicoplanin producing strain of Actinoplanes teichomyceticus. J. Antibiot. 52: 40-44.
4. Jin, Z. H., M. R. Wang, and P. L. Cen. 2002. Production of teicoplanin by valine analogue-resistant mutant strains of Actinoplanes teichomyceticus. Appl. Microbiol. Biotechnol. 58: 63-66.
5. Kim, D.-M., D.-W. Kim, J.-H. Lee, K.-H. Park, L.-M. Day, and D. F. Day. 1997. Development of constitutive dextransucrase hyper-producing mutants of Leuconostoc mesenteroides using the synchrotron radiation in the 70-1,000 eV region. Biotechnol. Tech. 11: 319-321.
6. Kim, S.-J., G.-J. Kim, D.-H. Park, and Y.-W. Ryu. 2003. High-level production of astaxanthin by fed-batch culture of mutant strain Phaffia rhodozyma AJ-6-1. J. Microbiol. Biotechnol. 13: 175-181.
7. Lee, H.-W., J. Yoon, J. H. Sohn, K.-H. Lee, B.-I. Yeh, D.-W. Park, H.-W. Kim, and J.-W. Choi. 2003. Detection of MecA gene in clinical isolates of Staphylococcus aureus by multiplex-PCR, and antimicrobial susceptibility of MRSA. J. Microbiol. Biotechnol. 13: 354-359.
8. Lee, J.-C., H.-R. Park, D.-J. Park, H.-B. Lee, Y.-B. Kim, and C.-J. Kim. 2003. Improved production of teicoplanin using adsorbent resin in fermentations. Lett. Appl. Microbiol. 37: 196-200.
9. Lee, J.-C., H.-R. Park, D.-J. Park, K.-H. Son, K.-H. Yoon, Y.-B. Kim, and C.-J. Kim. 2003. Production of teicoplanin by a mutant of Actinoplanes teichomyceticus. Biotechnol. Lett. 25: 537-540.
10. Lee, J.-C., H.-R. Park, D.-J. Park, Y.-B. Kim, and C.-J. Kim. 2003. Separation and purification of teicoplanin by Diaion HP-20 and concanavalin A chromatography. Kor. J. Appl. Microbiol. Biotechnol. 31: 201-204.
11. Parenti, F., G. Beretta, M. Berti, and V. Arioli. 1978. Teicomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. I. Description of the producer strain, fermentation studies and biological properties. J. Antibiot. 31: 276-283.
12. Plackett, R. L. and J. P. Burman. 1946. The design of optimuni multifactorial experiments. Biometrica 33: 305-325.
13. Ryu, Y. G., W. Jin, J. Y. Kim, J. Y. Kim, S. H. Lee, and K. J. Lee. 2004. Stringent factor regulates antibiotics production and morphological differentiation of Streptomyces clavuligerus. J. Microbiol. Biotechnol. 14: 1170-1175.
14. Sosio, M., H. Kloosterman, A. Bianchi, P. Vreugd, L. Dijkhuizen, and S. Donadio. 2004. Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus. Microbiology 150: 95-102.