AI-700 Acusphere

Current Opinion in Investigational Drugs

Volumn 6, Issue 9, 2005, Pages 956-961

  Hamilos, Michael I ^a   Patrianakos, Alexandros P ^a  

^a UNIVERSITY HOSPITAL OF IRAKLION   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

AI 700; ALBUNEX; CONTRAST MEDIUM; DIPYRIDAMOLE; ECHO CONTRAST MEDIUM; FS 069; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MICROSPHERE; NC 100100; PLACEBO; POLYMER; SENOVUE; SHU 508; THALLIUM 201; UNCLASSIFIED DRUG;

ANGIOCARDIOGRAPHY; CLINICAL TRIAL; CONTRAST ECHOCARDIOGRAPHY; DIAGNOSTIC VALUE; DRUG HALF LIFE; DRUG INDUSTRY; DRUG SYNTHESIS; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART VENTRICLE EXTRASYSTOLE; HUMAN; IMAGING SYSTEM; MICROANGIOPATHY; NONHUMAN; PATENT; REVIEW; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING; ULTRASOUND;

CLINICAL TRIALS; CONTRAST MEDIA; ECHOCARDIOGRAPHY; FLUOROCARBONS; HUMANS; MYOCARDIAL ISCHEMIA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 24644445149     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. 305878 Acusphere announces key patent issuance. Acusphere Inc PRESS RELEASE 1998 November 17
2. 310650 Acusphere announces patent issuance on ultrasound contrast agent technology. Acusphere Inc PRESS RELEASE 1999 January 05
3. 328109 AI-700, a new ultrasound contrast agent allows reliable detection of hypoperfused zones in acute ischemia and infarction not only in triggered mode but also in continuous imaging mode. Yao J, Takeuchi M, Taupe C, Sheahan M, Connolly R, Walovitch R, Fetterman R, Church C, Udelson J, Pandian N J AM COLL CARDIOL 1999 33 2 Suppl A 446A-447A
4. 334132 Acusphere completes phase 1 safety and myocardial perfusion imaging trial of ultrasound contrast agent. Acusphere Inc PRESS RELEASE 1999 July 27
5. 405530 Contrast echocardiography: Current and future applications. Mulvagh SL, DeMaria AN, Feinstein SB, Burns PN, Kaul S, Miller JG, Monaghan M, Porter TR, Shaw LJ, Villanueva FS J AM SOC ECHOCARDIOGR 2000 13 4 331-342
6. 405531 Ultrasound contrast imaging: Current and new potential methods. Frinking PJA, Bouakaz A, Kirkhorn J, TenCatef J, DeJong N ULTRASOUND MED BIOL 2000 26 6 965-975
7. 405533 Hypoperfused myocardial mass estimated from 3-dimensional contrast echocardiography using a novel contrast agent, AI-700, aids in accurate quantitation of infarct mass. Yao J, Takeuchi M, Teupe C, Sheehan M, Connolly R, Walovitch R, Fetterman R, Church C, Pandian N J AM COLL CARDIOL 1999 33 2 Suppl A 467A
8. 422634 Ultrasound imaging enhanced by Acusphere's AI-700 shows potential to improve coronary artery disease diagnosis. Acusphere Inc PRESS RELEASE 2001 July 19
9. 486404 Acusphere Inc announces $20 million in private financing. Acusphere Inc PRESS RELEASE 2003 April 21
10. 517530 Acusphere Inc commences pivotal phase of AI-700 phase III clinical program. Acusphere Inc PRESS RELEASE 2003 December 18
11. 547200 Acusphere's coronary contrast agent shows positive clinical results. Acusphere Inc PRESS RELEASE 2004 July 01
12. 547897 Acusphere announces $70 million European partnership for AI-700. Acusphere Inc PRESS RELEASE 2004 July 07
13. 548818 Evaluation of a new ultrasound contrast agent (AI-700) using two-dimensional and three-dimensional imaging during acute ischemia. Yao J, Takeuchi M, Taupe C, Sheahan M, Connolly R, Walovitch RC, Fetterman RC, Church CC, Udelson JE, Pandian NG J AM SOC ECHOCARDIOGR 2002 15 7 686-694
14. 548820 Microbubbles in medical imaging: Current applications and future directions. Lindner JR NAT REV DRUG DISCOV 2004 3 6 527-532
15. 548822 Physical principles of microbubble ultrasound contrast agents. Raisinghani A, DeMaria AN AM J CARDIOL 2002 90 10 Suppl 1 3J-7J
16. 548823 Myocardial contrast agents: Recent advances and future directions. Mayer S, Grayburn PA PROG CARDIOVASC DIS 2001 44 1 33-44
17. 570757 Acusphere Inc reports third quarter financial results and operating highlights. Acusphere Inc PRESS RELEASE 2004 November 12
18. 578656 Acusphere's AI-700 pilot study exceeds expectations. Acusphere Inc PRESS RELEASE 2005 January 06
19. 595038 Acusphere expands AI-700 phase 3 trials. Acusphere Inc PRESS RELEASE 2005 April 13
20. 600969 Acusphere Inc reports Q1 financial results and operating highlights. Acusphere Inc PRESS RELEASE 2005 May 12
21. 612027 The acoustical responses of AI-700 in vitro. Church C J AM SOC ECHOCARDIOGR 2000 13 457 Abs
22. 612218 Contrast echocardiography: New Agents. Miller AP, Nanda NC ULTRASOUND MED BIOL 2004 30 4 425-434
23. 612333 Initial safety and myocardial perfusion imaging results with AI-70O™: A new ultrasound contrast agent. Walovitch RC, Kwan OL, Picard MH, Church CC, Milstein AM, Fetterman RC, Zelle RE, Bernstein H, DeMaria AN J AM SOC ECHOCARDIOGR 2000 13 457 Abs
24. 612436 Chronotropic response after dipyridamole correlates with increased AI-700 echo and nuclear perfusion sensitivity in patients screened for coronary disease. Weissman NJ, Grayburn PA, Zoghbi WA, Klein AL, Walovitch RC, Picard MH J AM SOC ECHOCARDIOGR 2004 17 5 514
25. 612439 Comparison of AI-700 echo and nuclear perfusion imaging to coronary angiography in patients with suspected coronary disease. Grayburn PA, Zoghbi WA, Weissman NJ, Klein AL, Pano A, Walovitch RC, Picard MH J AM SOC ECHOGARDIOGR 2004 17 5 502
26. 612458 The effects of AI-700 echo-contrast perfusion and/or wall motion imaging on detection of perfusion defects in patients with coronary artery disease. Picard M, Pandian N, Morcerf F, Wackers F, Udelson JE, Weissmann N, Grayburn P, Klein A, Vannan M, Yao J, Fetterman R et al J AM SOC ECHOCARDIOGR 2001 14 5 460
27. 99mTc MIBI Spect in patients with myocardial perfusion defects: A phase 2 study of AI-700. Weisman N, Grayburn P, Klein A, Vannan M, Church C, Wackers F, Udelson J, Pandian N, Morcerf F, DeMaria A, Walovitch R, Picard M J AM SOC ECHOCARDIOGR 2001 14 5 461
28. 612536 Delivery at colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound. Price RJ, Skyba DM, Kaul S, Skalak TC CIRCULATION 1998 98 13 1264-1267
29. 612537 Premature ventricular contractions during triggered imaging with ultrasound contrast. van der Wouw PA, Brauns AC, Bailey SE, Powers JE, Wilde AA J AM SOC ECHOCARDIOGR 2000 13 4 288-294
30. 614151 Quantification of myocardial perfusion with myocardial contrast echocardiography during left atrial injection of contrast. Implications for venous injection. CIRCULATION 1994 90 3 1513-1521
31. 614485 AI-700, our ultrasound contrast agent. Acusphere Inc COMPANY WORLD WIDE WEB SITE 2005 July 22