Evaluation of a new ultrasound contrast agent (AI-700) using two-dimensional and three-dimensional imaging during acute ischemia

Journal of the American Society of Echocardiography

Volumn 15, Issue 7, 2002, Pages 686-694

  Yao, Jiefen ^a   Takeuchi, Masaaki ^a   Teupe, Claudius ^a   Sheahan, Malachi ^a   Connolly, Raymond ^a   Walovitch, Richard C ^a   Fetterman, Robert C ^a   Church, Charles C ^a   Udelson, James E ^a   Pandian, Natesa G ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST MEDIUM; DIAGNOSTIC AGENT; FLUOROCARBON; LACTIC ACID; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER; RADIOPHARMACEUTICAL AGENT; TRIPHENYLTETRAZOLIUM;

ANIMAL; ARTICLE; DISEASE MODEL; DOG; ECHOGRAPHY; EVALUATION; HEART MUSCLE ISCHEMIA; IMAGE ENHANCEMENT; IMAGE PROCESSING; THREE DIMENSIONAL ECHOCARDIOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; CADAVER; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DOPPLER ECHOCARDIOGRAPHY; HEART INFARCTION; NONHUMAN;

ANIMALS; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; DOGS; ECHOCARDIOGRAPHY, THREE-DIMENSIONAL; FLUOROCARBONS; IMAGE ENHANCEMENT; IMAGE PROCESSING, COMPUTER-ASSISTED; LACTIC ACID; MICROSPHERES; MYOCARDIAL ISCHEMIA; POLYGLYCOLIC ACID; POLYMERS; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M SESTAMIBI;

EID: 19044387992     PISSN: 08947317     EISSN: None     Source Type: Journal    
DOI: 10.1067/mje.2002.119114     Document Type: Article

References (16)

1. Kaul S. Myocardial contrast echocardiography in coronary artery disease: potential applications using venous injections of contrast. Am J Cardiol 1995;75:61D-8D.
2. 99mTc-sestamibi single-photon emission computed tomography. Circulation 1997;996:785-92.
3. Aronson S. Measurement of myocardial perfusion by contrast echocardiography: application in the operating room. Coron Artery Dis 2000;11:227-34.
4. Jucquois I, Nihoyannopoulos P, D’Hondt AM, Roelants V, Robert A, Melin JA, et al. Comparison of myocardial contrast echocardiography with NC100100 and (99m)Tc sestamibi SPECT for detection of resting myocardial perfusion abnormalities in patients with previous myocardial infarction. Heart 2000;83:518-24.
5. Villanueva FS. The use of myocardial contrast echocardiography in clinical evaluation after myocardial infarction. Coron Artery Dis 2000;11:235-42.
6. Porter TR, Kriesfeld D, Cheatham S, Li S. The effect of ultrasound frame rate on perfluorocarbon-exposed sonicated dextrose albumin microbubble size and concentration when insonifying at different flow rates, transducer frequencies, and acoustic outputs. J Am Soc Echocardiogr 1997;10:593-601.
7. Porter TR, Xie F, Li S, D’Sa A, Rafter P. Increased ultrasound contrast and decreased microbubble destruction rates with triggered ultrasound imaging. J Am Soc Echocardiogr 1996;9:599-605.
8. Porter TR, Li S, Kriesfeld D, Armbruster RW. Detection of myocardial perfusion in multiple echocardiographic windows with one intravenous injection of microbubbles using transient response second harmonic imaging. JACC 1997;29:791-9.
9. Porter TR, Li S, Jiang L, Grayburn P, Deligonul U. Real-time visualization of myocardial perfusion and wall thickening in human beings with intravenous ultrasonographic contrast and accelerated intermittent harmonic imaging. J Am Soc Echocardiogr 1999;12:266-71.
10. Yao J, De Castro S, Delabays A, Masani N, Udelson JE, Pandian NG. "Bulls-eye" display and quantitation of myocardial perfusion defects using 3D contrast echocardiography. Echocardiography 2001;18:581-8.
11. Dilsizian V, Bonow RO. Current diagnostic techniques of assessing myocardial viability in patients with hibernating and stunned myocardium. Circulation 1993;87:1-20.
12. Nagy A, Lengyel M, Rovai D, Morales MA, Marzilli M, Distante A, et al. Contrast echocardiography in the diagnosis of myocardial stunning. Clin Cardiol 1999;22:816-8.
13. Becher H, Burns PN, eds. Left ventricular function and myocardial perfusion. In: Becher H, Burns PN, editors. Handbook of contrast echocardiography. New York, NY: Springer-Verlag New York; 2000.
14. Church CC. The acoustical response of AI-700 in vitro [abstract]. J Am Soc Echocardiogr 2000;13:457.
15. Walovitch RC, Kwan QL, Picard MH, Church CC, Milstein AM, Fetterman RC, et al. Initial safety and myocardial perfusion imaging results with AI-700: a synthetic polymeric ultrasound contrast agent [abstract]. J Am Soc Echocardiogr 2000;13:457.
16. Tiemann K, Lohmeier S, Kuntz S, Köster J, Pohl C, Burns P, et al. Real-time contrast echo assessment of myocardial perfusion at low emission power: first experimental and clinical results using power puise inversion imaging. Echocardiography 1999;16:799-809.