The folding energy landscape and phosphorylation: Modeling the conformational switch of the NFAT regulatory domain

FASEB Journal

Volumn 19, Issue 11, 2005, Pages 1389-1395

  Shen, Tongye ^a,b   Zong, Chenghang ^a,b   Hamelberg, Donald ^b,c   McCammon, J Andrew ^a,b,c   Wolynes, Peter G ^a,b  

^a Department of Chemistry and Biochemistry ^*  (United States)

^b Center for Theoretical Biological Physics   (United States)

^c University of California San Diego   (United States)

Author keywords

Conformational switch; Contact map PCA; Effective charge; Multi phosphorylation; Transcription factor

Indexed keywords

TRANSCRIPTION FACTOR NFAT;

ARTICLE; CONFORMATIONAL TRANSITION; ENERGY; HUMAN; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY;

EID: 24644442164     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.04-3590hyp     Document Type: Article

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