Angiopoietins are expressed in the normal rat pituitary gland

Endocrine Pathology

Volumn 16, Issue 1, 2005, Pages 67-73

  Nag, Sukriti ^a,c   Nourhaghighi, Nima ^a   Venugopalan, Roopa ^a   Asa, Sylvia L ^a   Stewart, Duncan J ^b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Angiopoietins; Gonadotrophs; Pituitary gland; Tie 2; Vascular endothelial growth factor

Indexed keywords

ADENOHYPOPHYSIS HORMONE; ANGIOPOIETIN; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; FOLLITROPIN; LUTEINIZING HORMONE; MESSENGER RNA; VASCULOTROPIN;

ADENOHYPOPHYSIS; ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONFOCAL MICROSCOPY; ENDOTHELIUM CELL; HYPOPHYSIS; HYPOPHYSIS CELL; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; NEUROHYPOPHYSIS; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE LEVEL;

EID: 24644433346     PISSN: 10463976     EISSN: None     Source Type: Journal    
DOI: 10.1385/ep:16:1:067     Document Type: Article

References (34)

1. Gross PM, Sposito NM, Pettersen SE, Fenstermacher JD. Differences in function and structure of the capillary endothelium in gray matter, white matter and a circum-ventricular organ of rat brain. Blood Vessels 23:261-270, 1986.
2. Jugenburg M, Kovacs K, Stefaneanu L, Scheithauer BW. Vasculature in nontumorous hypophyses, pituitary adenomas, and carcinomas: a quantitative morphological study. Endocr Pathol 6:115-124, 1995.
3. Turner HE, Nagy Z, Gatter KC, Esiri MM, Harris AL, Wass JAH. Angiogenesis in pituitary adenomas and the normal pituitary gland. J Clin Endocrinol Metab 85:1159-1162, 2000.
4. Viacava P, Gasperi M, Acerbi G, et al. Microvascular density and vascular endothelial growth factor expression in normal pituitary tissue and pituitary adenomas. J Endocrinol Invest 26:23-28, 2003.
5. Vidal S, Scheithauer BW, Kovacs K. Vascularity in nontumorous human pituitaries and incidental microadenomas: a morphometric study. Endocr Pathol 11:215-227, 2000.
6. Lloyd RV, Vidal S, Horvath E, Kovacs K, Scheithauer B. Angiogenesis in normal and neoplastic pituitary tissues. Micros Res Tech 60:244-250, 2003.
7. Gospodarowicz D, Abraham JA, Schilling J. Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo-stellate cells. Proc Natl Acad Sci USA 86:7311-7315, 1989.
8. Turner HE, Harris AL, Melmed S, Wass JAH. Angiogenesis in endocrine tumors. Endocr Rev 24:600-632, 2003.
9. Ochoa AL, Mitchner NA, Paynter CD, Morris RE, Ben-Jonathan N. Vascular endothelial growth factor in the rat pituitary: differential distribution and regulation by estrogen. J Endocrinol 165:483-492, 2000.
10. Lloyd RV, Scheithauer BW, Kuroki T, Vidal S, Kovacs K, Stefaneanu L. Vascular endothelial growth factor VEGF) expression in human pituitary adenomas and carcinomas. Endocr Pathol 10:229-235, 1999.
11. Turner HE, Nagy Z S, Bromhall L, Esiri MM, Harris AL, Wass JAH. Vascular endothelial growth factor is elevated in patients with pituitary tumors. J Endocrinol 161:P215, 2000.
12. Vidal S, Lloyd RV, Moya L, Scheithauer BW, Kovacs K. Expression and distribution of vascular endothelial growth factor receptor flk-1 in the rat pituitary. J Histochem Cytochem 50:533-540, 2002.
13. Ferrara N, Houck K, Jakeman L, Leung DW. Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocr Rev 13:18-32, 1992.
14. Hanahan D. Signaling vascular morphogenesis and maintenance. Science 277:48-50, 1997.
15. Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277:55-60, 1997.
16. Peters KG. Vascular endothelial growth factor and the angiopoietins: working together to build a better blood vessel. Circ Res 83:342-343, 1998.
17. Davis S, Aldrich TH, Jones PF, et al. Isolation of angiopoietin-1, a ligand for the Tie2 receptor, by secretion-trap expression cloning. Cell 87:1161-1169, 1996.
18. Valenzuela DM, Griffiths J, Rojas J, et al. Angiopoietin 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci USA 96:1904-1909, 1999.
19. Dumont DJ, Gradwohl GJ, Fong GH, Auerbach R, Breitman ML. The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors. Oncogene 8:1293-1301, 1993.
20. Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380:435-439, 1996.
21. Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380:439-442, 1996.
22. Gerber HP, Hillan KJ, Ryan AM, et al. VEGF is required for growth and survival in neonatal mice. Development 126:1149-1159, 1999.
23. Hayes AJ, Huang WQ, Mallah J, Yang D, Lippman ME, Li LY. Angiopoietin-1 and its receptor Tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells. Microvasc Res 58:224-237, 1999.
24. Papapetropoulos A, Garcia-Cardena G, Dengler TJ, Maisonpierre PC, Yancopoulos GD, Sessa WC. Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. Lab Invest 79:213-223, 1999.
25. Yuan HT, Suri C, Landon DN, Yancopoulos GD, Woolf AS. Angiopoietin-2 is a site specific factor in the differentiation of mouse renal vasculature. J Am Soc Nephrol 11:1055-1066, 2000.
26. Nourhaghighi N, Teichert-Kuliszewska, K, Davis J, Stewart, DJ, Nag S. Altered expression of angiopoietins during BBB breakdown and angiogenesis. Lab Invest 83:1211-1222, 2003.
27. Nag S. Immunohistochemical detection of endothelial proteins. Methods Mol Med 89:491-503, 2003.
28. Otani A, Takagi H, Oh H, Koyama S, Honda Y. Angiotensin II induces expression of the Tie-2 receptor ligand, angiopoietin-2, in bovine retinal endothelial cells. Diabetes 50:867-875, 2001.
29. Goede V, Schmidt T, Kimmina S, Kozian D, Augustin HG. Analysis of blood vessel maturation processes during cyclic ovarian angiogenesis. Lab Invest 78:1385-1394, 1998.
30. Horner A, Bord S, Kelsall AW, Coleman N, Compston JE. Tie-2 ligands angiopoietin-1 and angiopoietin-2 are coexpressed with vascular endothelial growth factor in growing human bone. Bone 28:65-71, 2001.
31. Fan L, Iseki S. Immunohistochemical localization of vascular endothelial growth factor in the endocrine glands of the rat. Arch Histol Cytol 61:17-28, 1998.
32. Vidal SV, Kovacs K, Cohen SM, Stefaneanu L, Lloyd RV, Scheithauer BW. Localization of vascular endothelial growth factor in non-tumorous human pituitaries. Endocr Pathol 10:109-122, 1999.
33. Anasti JN, Kalantaridou SN, Kimzey LM, George M, Nelson LM. Human follicle fluid vascular endothelial growth factor concentrations are correlated with luteinization in spontaneously developing follicles. Hum Reprod 13:1144-1147, 1998.
34. Artini PG, Monti M, Fasciani A, Tartaglia ML, D'Ambrogio G, Genazzani AR. Correlation between the amount of follicle stimulating hormone administered and plasma and follicular fluid vascular endothelial growth factor concentrations in women undergoing in vitro fertilization. Gynecol Endocrinol 12:243-247, 1998.