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Volumn 15, Issue 7, 1999, Pages 633-645

Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection

(26)  Salmon Céron, Dominique a,l   Excler, Jean Louis b,c   Finkielsztejn, Laurent a   Autran, Brigitte d   Gluckman, Jean Claude d   Sicard, Didier a   Matthews, Thomas J e   Meignier, Bernard b   Valentin, Christian b   El Habib, Raphaëlle b   Blondeau, Christine b   Raux, Maurice b   Moog, Christiane f   Tartaglia, James g   Chong, Pele b   Klein, Michel b   Milcamps, Bruno b   Heshmati, Farad a   Plotkin, Stanley b   Girard, Marc h   more..

f INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY; PROTEINASE; VIRUS GLYCOPROTEIN;

EID: 2442758677     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922299310935     Document Type: Article
Times cited : (59)

References (43)
  • 1
    • 0030571189 scopus 로고    scopus 로고
    • HIV vaccines: Where we are and where we are going
    • Haynes BF: HIV vaccines: Where we are and where we are going. Lancet 1996;348:933-937.
    • (1996) Lancet , vol.348 , pp. 933-937
    • Haynes, B.F.1
  • 5
    • 0031038629 scopus 로고    scopus 로고
    • HIV type 1 vaccine-induced cytotoxic T-cell responses: Potential role in vaccine efficacy
    • Ada GL and McElrath MJ: HIV type 1 vaccine-induced cytotoxic T-cell responses: Potential role in vaccine efficacy. AIDS Res Hum Retroviruses 1997;13:205-210.
    • (1997) AIDS Res Hum Retroviruses , vol.13 , pp. 205-210
    • Ada, G.L.1    McElrath, M.J.2
  • 8
    • 0025741252 scopus 로고
    • Genomic diversity and antigenie variation of HIV-1: Links between pathogenesis, epidemiology and vaccine development
    • Goudsmit J, Back NKT, and Nara PL: Genomic diversity and antigenie variation of HIV-1: Links between pathogenesis, epidemiology and vaccine development. FASEB J 1991;5:2427-2436.
    • (1991) FASEB J , vol.5 , pp. 2427-2436
    • Goudsmit, J.1    Back, N.K.T.2    Nara, P.L.3
  • 9
    • 0027195806 scopus 로고
    • Cytotoxic T-cell epitopes in HIV/SIV infection
    • Venet A and Walker BD: Cytotoxic T-cell epitopes in HIV/SIV infection. AIDS 1993;7(S1):S117-S126.
    • (1993) AIDS , vol.7 , Issue.S1
    • Venet, A.1    Walker, B.D.2
  • 10
    • 0023685463 scopus 로고
    • HIV-1 Gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides
    • Nixon D, Townsend A, Elvin J, Rizza CR, Gallwey J, and McMichael AJ: HIV-1 Gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides. Nature (London) 1988;336:484-487.
    • (1988) Nature (London) , vol.336 , pp. 484-487
    • Nixon, D.1    Townsend, A.2    Elvin, J.3    Rizza, C.R.4    Gallwey, J.5    McMichael, A.J.6
  • 11
    • 0029898314 scopus 로고    scopus 로고
    • Non-replicating expression vectors: Applications in vaccine development and gene therapy
    • Limbach KJ and Paoletti E: Non-replicating expression vectors: Applications in vaccine development and gene therapy. Epidemiol Infect 1996;116:241-256.
    • (1996) Epidemiol Infect , vol.116 , pp. 241-256
    • Limbach, K.J.1    Paoletti, E.2
  • 12
    • 19244362119 scopus 로고    scopus 로고
    • Memory cytotoxic T lymphocyte responses in human immunodeficiency virus type 1 (HIV-1)-negative volunteers immunized with a recombinant canarypox expressing gp160 of HIV-1 and boosted with a recombinant gp160
    • Fleury B, Janvier G, Pialoux G, Buseyne F, Robertson MN, Tartaglia J, Paoletti E, Kieny MP, Excler JL, and Rivière Y: Memory cytotoxic T lymphocyte responses in human immunodeficiency virus type 1 (HIV-1)-negative volunteers immunized with a recombinant canarypox expressing gp160 of HIV-1 and boosted with a recombinant gp160. J Infect Dis 1996;174:734-738.
    • (1996) J Infect Dis , vol.174 , pp. 734-738
    • Fleury, B.1    Janvier, G.2    Pialoux, G.3    Buseyne, F.4    Robertson, M.N.5    Tartaglia, J.6    Paoletti, E.7    Kieny, M.P.8    Excler, J.L.9    Rivière, Y.10
  • 14
    • 0025328626 scopus 로고
    • Identification of a potent synthetic HIV-1 immunogen comprising Gag-p24 tandem T- and B-cell epitopes
    • Chong P, Sia C, Sydor M, and Klein M: Identification of a potent synthetic HIV-1 immunogen comprising Gag-p24 tandem T-and B-cell epitopes. FEBS Lett 1990;164:231-234.
    • (1990) FEBS Lett , vol.164 , pp. 231-234
    • Chong, P.1    Sia, C.2    Sydor, M.3    Klein, M.4
  • 16
    • 0028013738 scopus 로고
    • Primary in vitro sensitization of human T helper lymphocytes by peptides derived from the V3 loop of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein
    • Billaud JN, Yagello M, and Gluckman JC: Primary in vitro sensitization of human T helper lymphocytes by peptides derived from the V3 loop of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein. Vaccine 1994;12:46-55.
    • (1994) Vaccine , vol.12 , pp. 46-55
    • Billaud, J.N.1    Yagello, M.2    Gluckman, J.C.3
  • 18
    • 0025133392 scopus 로고
    • Immunogenicity of the human immunodeficiency virus (HIV) recombinant nef gene product. Mapping of T-cell and B-cell epitopes in immunized chimpanzees
    • Bahraoui E, Yagello M, Billaud JN, Sabatier JM, Guy B, Muchmore E, Girard M, and Gluckman JC: Immunogenicity of the human immunodeficiency virus (HIV) recombinant nef gene product. Mapping of T-cell and B-cell epitopes in immunized chimpanzees. AIDS Res Hum Retroviruses 1990;6:1087-1098.
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 1087-1098
    • Bahraoui, E.1    Yagello, M.2    Billaud, J.N.3    Sabatier, J.M.4    Guy, B.5    Muchmore, E.6    Girard, M.7    Gluckman, J.C.8
  • 20
    • 0027237806 scopus 로고
    • Antibodies to recombinant gp160 in mucosal secretions and sera of persons infected with HIV-1 and seronegative vaccine recipients
    • Funkhouser A, Clements ML, Slome S, Clayman B, and Viscidi R: Antibodies to recombinant gp160 in mucosal secretions and sera of persons infected with HIV-1 and seronegative vaccine recipients. AIDS Res Hum Retroviruses 1993;9:627-632.
    • (1993) AIDS Res Hum Retroviruses , vol.9 , pp. 627-632
    • Funkhouser, A.1    Clements, M.L.2    Slome, S.3    Clayman, B.4    Viscidi, R.5
  • 24
    • 0029947256 scopus 로고    scopus 로고
    • Human safety and immunogenicity of a canarypox-rabies glycoprotein recombinant vaccine: An alternative poxvirus vector system
    • Fries LF, Tartaglia J, Taylor J, Kauffman EK, Meignier B, Paoletti E, and Plotkin S: Human safety and immunogenicity of a canarypox-rabies glycoprotein recombinant vaccine: An alternative poxvirus vector system. Vaccine 1996;14:428-434.
    • (1996) Vaccine , vol.14 , pp. 428-434
    • Fries, L.F.1    Tartaglia, J.2    Taylor, J.3    Kauffman, E.K.4    Meignier, B.5    Paoletti, E.6    Plotkin, S.7
  • 25
    • 0029055312 scopus 로고
    • Utility of various commercially available human immunodeficiency virus (HIV) antibody diagnostic kits for use in conjunction with efficacy trials of HIV-1 vaccines
    • Schwartz DH, Mazumdar A, Winston S, and Harkonen S: Utility of various commercially available human immunodeficiency virus (HIV) antibody diagnostic kits for use in conjunction with efficacy trials of HIV-1 vaccines. Clin Diag Lab Immunol 1995;2:268-271.
    • (1995) Clin Diag Lab Immunol , vol.2 , pp. 268-271
    • Schwartz, D.H.1    Mazumdar, A.2    Winston, S.3    Harkonen, S.4
  • 28
    • 19144370387 scopus 로고    scopus 로고
    • Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1
    • Berman PW, Murthy KK, Wrin T, et al.: Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1. J Infect Dis 1996;173:52-59.
    • (1996) J Infect Dis , vol.173 , pp. 52-59
    • Berman, P.W.1    Murthy, K.K.2    Wrin, T.3
  • 29
    • 0028892847 scopus 로고
    • Resistance of chimpanzees immunized with recombinant gp120 (SF2) to challenge by HIV-1 (SF2)
    • El Amad Z, Murthy KK, Heggins K, et al: Resistance of chimpanzees immunized with recombinant gp120 (SF2) to challenge by HIV-1 (SF2). AIDS 1995;9:1313-1322.
    • (1995) AIDS , vol.9 , pp. 1313-1322
    • El Amad, Z.1    Murthy, K.K.2    Heggins, K.3
  • 31
    • 0027280516 scopus 로고
    • Mother-to-child transmission of human immunodeficiency virus type 1: Correlation with neutralizing antibodies against primary isolates
    • Scarlatti G, Albert J, Rossi P, et al.: Mother-to-child transmission of human immunodeficiency virus type 1: Correlation with neutralizing antibodies against primary isolates. J Infect Dis 1993;168:207-210.
    • (1993) J Infect Dis , vol.168 , pp. 207-210
    • Scarlatti, G.1    Albert, J.2    Rossi, P.3
  • 32
    • 2442725544 scopus 로고    scopus 로고
    • Protection from intravenous and genital HIV-1 challenge in chimpanzees by immunization with an HIV-1 canarypox recombinant. Annual Meeting of the Institute of Human Virology, Baltimore, Maryland
    • Abstract 165
    • Girard M, Barré-Sinoussi F, Tartaglia J, Paoletti E, Van der Ryst E, Nara P, Muchmore E, Mahoney J, Jennings M, and Fultz P: Protection from intravenous and genital HIV-1 challenge in chimpanzees by immunization with an HIV-1 canarypox recombinant. Annual Meeting of the Institute of Human Virology, Baltimore, Maryland. J Acq Immun Defic Synd Hum R 1996. [Abstract 165]
    • (1996) J Acq Immun Defic Synd Hum R
    • Girard, M.1    Barré-Sinoussi, F.2    Tartaglia, J.3    Paoletti, E.4    Van Der Ryst, E.5    Nara, P.6    Muchmore, E.7    Mahoney, J.8    Jennings, M.9    Fultz, P.10
  • 34
    • 0028944192 scopus 로고
    • HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women
    • Rowland-Jones S, Sutton J, Ariyoshi K, et al.: HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nature Med 1995;1:59-64.
    • (1995) Nature Med , vol.1 , pp. 59-64
    • Rowland-Jones, S.1    Sutton, J.2    Ariyoshi, K.3
  • 35
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, et al.: Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994; 68:4650-4655.
    • (1994) J Virol , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3
  • 36
    • 0030219573 scopus 로고    scopus 로고
    • Evolution and plasticity of CTL responses against HIV
    • Autran B, Hadida F, and Haas G: Evolution and plasticity of CTL responses against HIV. Curr Opin Immunol 1996;8:546-553.
    • (1996) Curr Opin Immunol , vol.8 , pp. 546-553
    • Autran, B.1    Hadida, F.2    Haas, G.3
  • 37
    • 0028269850 scopus 로고
    • HIV Nef-specific cytotoxic T lymphocytes in non-infected heterosexual contacts of HIV-infected patients
    • Langlade-Demoyen P, Ngo-Giang-Huong N, Ferchal F, and Oskenhendler E: HIV Nef-specific cytotoxic T lymphocytes in non-infected heterosexual contacts of HIV-infected patients. J Clin Invest 1994;93:1293-1297.
    • (1994) J Clin Invest , vol.93 , pp. 1293-1297
    • Langlade-Demoyen, P.1    Ngo-Giang-Huong, N.2    Ferchal, F.3    Oskenhendler, E.4
  • 38
    • 0028041344 scopus 로고
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994;68:6103-6110.
    • (1994) J Virol , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewiski, H.2    Hahn, B.H.3
  • 39
    • 0027732311 scopus 로고
    • HIV-specific CD8+ T-cell immune responses and viral replication
    • Bunseyne F and Rivière Y: HIV-specific CD8+ T-cell immune responses and viral replication. AIDS 1993;7:S73-S79.
    • (1993) AIDS , vol.7
    • Bunseyne, F.1    Rivière, Y.2
  • 40
    • 0028978720 scopus 로고
    • Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex of AIDS
    • Rivière Y, McChesney MB, Porrot F, et al.: Gag-specific cytotoxic responses to HIV type 1 are associated with a decreased risk of progression to AIDS-related complex of AIDS. AIDS Res Hum Retroviruses 1995;11:903-907.
    • (1995) AIDS Res Hum Retroviruses , vol.11 , pp. 903-907
    • Rivière, Y.1    McChesney, M.B.2    Porrot, F.3
  • 41
    • 0026746352 scopus 로고
    • Cytotoxic T lymphocyte responses in the peripheral blood of children born to HIV-1 infected mothers
    • Cheynier R, Langlade-Demoyen P, Marescot MR, et al.: Cytotoxic T lymphocyte responses in the peripheral blood of children born to HIV-1 infected mothers. Eur J Immunol 1992;22:2211-2217.
    • (1992) Eur J Immunol , vol.22 , pp. 2211-2217
    • Cheynier, R.1    Langlade-Demoyen, P.2    Marescot, M.R.3


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