Aggravation of acute ischemic stroke by hyperthermia is related to an excitotoxic mechanism

Cerebrovascular Diseases

Volumn 9, Issue 1, 1999, Pages 22-27

  Castillo, José ^a,c   Dávalos, Antoni ^b   Noya, Manuel ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^b HOSPITAL JOSEP TRUETA   (Spain)

^c HOSPITAL GENERAL DE GALICIA   (Spain)

Author keywords

Cerebral ischemia; Excitatory amino acids; Glutamate; Glycine; Hyperthermia

Indexed keywords

EXCITATORY AMINO ACID; GLUTAMIC ACID; GLYCINE;

ADULT; AGED; ARTICLE; BODY TEMPERATURE; BRAIN INFARCTION; BRAIN ISCHEMIA; CEREBROSPINAL FLUID; CEREBROVASCULAR ACCIDENT; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; CRANIAL NERVE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOSPITAL ADMISSION; HUMAN; HYPERTHERMIA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ACUTE DISEASE; AGED; BODY TEMPERATURE REGULATION; DISEASE PROGRESSION; EXCITATORY AMINO ACIDS; FEMALE; GLUTAMINE; GLYCINE; HUMANS; ISCHEMIC ATTACK, TRANSIENT; LINEAR MODELS; MALE;

EID: 2442728247     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000015891     Document Type: Article

References (44)

1. Hindfelt B: The prognostic significance of subfebrility and fever in ischemic cerebral infarction. Acta Neurol Scand 1976;53:72-79.
2. Terent A, Andersen B: The prognosis for patients with cerebrovascular stroke and transient ischemic attacks. Ups J Med Sci 1981;86: 63-74.
3. Castillo J, Martínez F, Leira R, Prieto JM, Lema M, Noya M: Mortality and morbidity of acute cerebral infarction related to temperature and basal analytic parameters. Cerebrovasc Dis 1994;4:66-71.
4. Azzimondi G, Bassein L, Nomino F, Fiorani L, Vignatelli L, Re G, D'Alessandro R: Fever in acute stroke worsens prognosis: A prospective study. Stroke 1995;26:2040-2043.
5. Reith J, Jorgensen HS, Pedersen PM, Nakayama H, Raaschon HO, Jeppesen LL, Olsen TS: Body temperature in acute stroke: Relation to stroke severity, infarct size, mortality and outcome. Lancet 1996;347:422-425.
6. Dávalos A, Castillo J, Pumar JM, Noya M: Body temperature and fibrinogen are related to early neurological deterioration in acute ischemic stroke. Cerebrovasc Dis 1997;7:64-69.
7. Busto R, Dietrich WD, Globus MY-T, Valdés I, Scheinberg P, Ginsberg MD: Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab 1987;7:729-738.
8. Minamisawa H, Smith M-L, Siesjö BK: The effect of mild hyperthermia and hypothermia on brain damage following 5, 10 and 15 minutes of forebrain ischemia. Ann Neurol 1990; 28:26-33.
9. Ginsberg MD, Sternau LL, Globus MY-T, Dietrich WD, Busto R: Therapeutic modulation of brain temperature: Relevance to ischemic brain injury. Cerebrovasc Brain Metab Rev 1992;4:189-225.
10. Nemoto EM, Frankel HM: Cerebral oxygenation and metabolism during progressive hyperthermia. Am J Physiol 1970;219:1784-1788.
11. Lin B, Busto R, Globus MY-T, Martínez E, Ginsberg MD: Brain temperature modulations during global ischemia fail to influence extra-cellular lactate levels in rats. Stroke 1995;26: 1634-1638.
12. Baena RC, Busto R, Dietrich WD, Globus MY-T, Ginsberg MD: Hyperthermia delayed by 24 hours aggravates neuronal damage in rat hippocampus following global ischemia. Neurology 1997;48:768-773.
13. Sternau LL, Globus MY-T, Martinez E, Dietrich WD, Busto R, Ginsberg MD: Ischemia-induced neurotransmitter release: Effects of mild intraischemic hyperthermia; in Globus MY-T, Dietrich WD (eds): The Role of Neurotransmitters in Brain Injury. New York, Plenum Press, 1992, pp 33-38.
14. Baker CJ, Fiore AJ, Frazzini VI, Choudhri TF, Zubay GP, Solomon RA: Intraischemic hypothermia decreases the release of glutamate in the cores of permanent focal cerebral infarcts. Neurosurgery 1995;36:994-1002.
15. Nakashima K, Todd MM: Effects of hypothermia on the rate of excitatory amino acid release after ischemic depolarization. Stroke 1996;27: 913-918.
16. Butcher SP, Bullock R, Graham DI, McCulloch J: Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke 1990;21:1727-1733.
17. Takagi K, Ginsberg MD, Globus MY-T, Dietrich WD, Martínez E, Kraydieh S, Busto R: Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: Correlation with histopathology. J Cereb Blood Flow Metab 1993;13:575-585.
18. Kanthan R, Shuaib A, Griebel R, Miyashita H: lntracerebral human microdialysis: In vivo study of an acute focal ischemic model of the human brain. Stroke 1995;26:870-873.
19. Bullock R, Zauner A, Woodward J, Young HF: Massive persistent release of excitatory amino acids following human occlusive stroke. Stroke 1995;26:2187-2189.
20. Castillo J, Dávalos A, Naveiro J, Noya M: Neuroexcitatory amino acids and their relationship to infarct size and neurological deficit in ischemic stroke. Stroke 1996;27:1060-1065.
21. Castillo J, Dávalos A, Noya M: Progression of ischaemic stroke and excitatory amino acids. Lancet 1997;349:79-83.
22. Côté R, Hachinski VC, Shurvell BL, Norris JW, Wolfson C: The Canadian neurological scale: A preliminary study in acute stroke. Stroke 1986;17:731-737.
23. Spackman DH, Stein WH, Moore S: Automatic recording apparatus for use in the chromatography of amino acids. Anal Chem 1958;30: 1190-1206.
24. Turnell DC, Cooper JDH: Rapid assay for amino acids in serum or urine by pre-column derivation and reversed-phase liquid chromatography. Clin Chem 1982;28:527-531.
25. Dávalos A, Cendra E, Teruel J, Martínez M, Gemís D: Deteriorating ischemic stroke: Risk factors and prognosis. Neurology 1990;40: 1865-1869.
26. Oppenheimer S, Hachinski V: Complications of acute stroke. Lancet 1992; 339:721-724.
27. Folbergrove J, Memezawa H, Smith ML, Siesjö BK: Focal and perifocal changes in tissue energy state during middle cerebral artery occlusion in normo-and hyperglycemic rats. J Cereb Blood Flow Metab 1992;12:25-33.
28. Lo EH, Steinberg GK: Effects of hypothermia on evoked potentials, magnetic resonance imaging, and blood flow in focal ischemia in rabbits. Stroke 1992;23:889-893.
29. Dietrich WD, Alonso O, Busto R: Moderate hyperglycemia worsens acute blood-brain barrier injury after forebrain ischemia in rats. Stroke 1993;24:111-116.
30. Choi DW, Rothman SM: The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 1990;13:171-182.
31. Uchiyama-Tsuyuki Y, Araki H, Yae T, Otomo S: Changes in the extracellular concentrations of amino acids in the rat striatum during transient focal cerebral ischemia. J Neurochem 1994;62:1074-1078.
32. Matsumoto K, Graf R, Rosner G, Taguchi J, Heiss WD: Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemia. J Cereb Blood Flow Metab 1993;13: 586-594.
33. Shimada N, Graf R, Rosner G, Heiss WD: Ischemia-induced accumulation of extracellular amino acids in cerebral cortex, white matter, and cerebrospinal fluid. J Neurochem 1993;60:66-71.
34. Dávalos A, Castillo J, Serena J, Noya M: Duration of glutamate release after acute ischemic stroke. Stroke 1997;28:708-710.
35. Dávalos A, Castillo J: Potential mechanisms of worsening. Cerebrovasc Dis 1997;7(suppl 5): 19-24.
36. Wahl F, Obrenovitch TP, Hardy AM, Plotkine M, Boulu RG, Symon L: Glutamate effluxes from the rat striatum during focal cerebral ischemia: Time course and calcium dependency; in Krieglstein J, Oberpichler-Schwenk H (eds): Pharmacology of Cerebral Ischemia 1994. Stuttgart, Medpharm Scientific Publishers, 1994, pp 157-164.
37. Greenamyre JT, Porter HP: Anatomy and physiology of glutamate in CNS. Neurology 1994;44(suppl 8):S7-S13.
38. Castillo J, Dávalos A, Lema M, Serena J, Noya M: Glutamate is a marker for cerebral ischemia in cortical but not deep infarcts. Cerebrovasc Dis 1997;7:245-250.
39. Fern R, Waxman SG, Ranson SG: Modulation of anoxic injury in CNS white matter by adenosine, and interaction between adenosine and GABA. J Neurophysiol 1994;72:2609-2616.
40. Waxman SG: Different strokes in different folks: Unique molecular signatures of cortical and deep brain infarcts. Cerebrovasc Dis 1997; 7:243-244.
41. Stys PK, Waxman SG, Ranson BR: Effects of temperature on evoked electrical activity and anoxic injury in CNS white matter. J Cereb Blood Flow Metab 1992;12:977-986.
42. Kemp JA, Leeson PD: The glycine site of the NMDA receptor - Five years on. Trends Pharmacol Sci 1993;14:20-25.
43. Ginsberg MD, Busto R: Combating hyperthermia in acute stroke: A significant clinical concern. Stroke 1998;29:529-534.
44. Siesjö BK: Editorial comment. Neurosurgery 1995;36:1001.