γ-amino-substituted analogues of 1-[(S)-2,4-diaminobutanoyl]piperidine as highly potent and selective dipeptidyl peptidase II inhibitors

Journal of Medicinal Chemistry

Volumn 47, Issue 11, 2004, Pages 2906-2916

  Senten, Kristel ^a   Van Der Veken, Pieter ^a   De Meester, Ingrid ^a   Lambeir, Anne Marie ^a   Scharpé, Simon ^a   Haemers, Achiel ^a   Augustyns, Koen ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,4 DIAMINOBUTANOYL)PIPERIDINE; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE 2 INHIBITOR; ENZYME INHIBITOR; PIPERIDINE 2 NITRILE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKALINITY; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTIGENS, CD26; DIPEPTIDYL PEPTIDASES; PIPERIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 2442719012     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm031122f     Document Type: Article

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