Imaging wound healing using optical coherence tomography and multiphoton microscopy in an in vitro skin-equivalent tissue model

Journal of Biomedical Optics

Volumn 9, Issue 2, 2004, Pages 248-253

  Yeh, Alvin T ^a,b   Kao, Bunsho ^a,c   Jung, Woong Gyu ^a   Chen, Zhongping ^a   Nelson, J Stuart ^a   Tromberg, Bruce J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Texas A and M University   (United States)

^c SHOWA UNIVERSITY   (Japan)

Author keywords

Extracellular matrix; Multiphoton microscopy; Optical coherence tomography; Second harmonic generation; Tissue engineering; Two photon excited fluorescence

Indexed keywords

ARTICLE; BURN; CELL CULTURE; HUMAN; LASER; METHODOLOGY; MICROSCOPY; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; PATHOPHYSIOLOGY; PHOTON; SKIN; WOUND HEALING;

BURNS; CELLS, CULTURED; HUMANS; LASERS; MICROSCOPY; PHOTONS; SKIN; TOMOGRAPHY, OPTICAL COHERENCE; WOUND HEALING;

COHERENT LIGHT; COMPUTER SIMULATION; COMPUTERIZED TOMOGRAPHY; HISTOLOGY; IMAGE RECONSTRUCTION; LASER TISSUE INTERACTION; MEDICAL IMAGING; MICROSCOPIC EXAMINATION; NONINVASIVE MEDICAL PROCEDURES; PATHOLOGY; SECOND HARMONIC GENERATION;

EXTRACELLULAR MATRIX; IN VITRO EQUIVALENT TISSUE MODEL; INTRINSIC SIGNAL OPTICAL IMAGING; KERATINOCYTES; MULTIPHOTON MICROSCOPY; OPTICAL COHERENCE TOMOGRAPHY; TWO PHOTON EXCITED FLUORESCENCE;

TISSUE;

EID: 2442705677     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.1648646     Document Type: Article

References (21)

1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, and C. A. Puliafito, "Optical coherence tomography," Science 254, 1178-1181 (1991). (Pubitemid 21917444)
2. W. Denk, J. H. Strickler, and W. W. Webb, "Two-photon laser scanning fluorescence microscopy," Science 248, 73-76 (1990).
3. E. Bell, H. P. Ehrlich, D. J. Buttle, and T. Nakatsuji, "Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness," Science 211, 1052-1054 (1981). (Pubitemid 11131539)
4. A. El-Ghalbzouri, S. Gibbs, E. Lamme, C. A. Van Blitterswijk, and M. Ponec, "Effect of fibroblasts on epidermal regeneration," Br. J. Dermatol. 147, 230-243 (2002).
5. A. Agarwal, M. L. Coleno, V. P. Wallace, W. Y. Wu, C. H. Sun, B. J. Tromberg, and S. C. George, "Two-photon laser scanning microscopy of epithelial cell-modulated collagen density in engineered human lung tissue," Tissue Eng. 7, 191-202 (2001). (Pubitemid 32295153)
6. Collagen, edited by M. E. Nimni (Chemical Rubber, Boca Raton, FL,1988).
7. I. S. Saidi, S. L. Jacques, and F. K. Tittel, "Mie and Rayleigh modeling of visible-light scattering in neonatal skin," Appl. Opt. 34, 7410-7418 (1995).
8. B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography, " J. Biomed. Opt. 6, 474-479 (2001). (Pubitemid 34228387)
9. J. F. de Boer, T. E. Milner, M. J. C. van Gemert, and J. S. Nelson, "Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography," Opt. Lett. 22, 934-936 (1997). (Pubitemid 127561994)
10. A. T. Yeh, N. Nassif, A. Zoumi, and B. J. Tromberg, "Selective corneal imaging using combined second harmonic generation and two-photon excited fluorescence," Opt. Lett. 27, 2082-2084 (2002).
11. P. J. Campagnola, A. C. Millard, M. Terasaki, P. E. Hoppe, C. J. Malone, and W. A. Mohler, "Three-dimensional high-resolution second-harmonic generation imaging of endogenous structural proteins in biological tissues," Biophys. J. 81, 493-508 (2002). (Pubitemid 34289822)
12. R. M. Williams, W. R. Zipfel, and W. W. Webb, "Multiphoton microscopy in biological research," Curr. Opin. Chem. Biol. 5, 603-608 (2001 ). (Pubitemid 32907614)
13. P. Stoller, B.-M. Kim, A. M. Rubenchik, K. M. Reiser, and L. B. Da Silva, "Polarization-dependent optical second-harmonic imaging of a rat-tail tendon," J. Biomed. Opt. 7, 205-214 (2002). (Pubitemid 34699145)
14. P. Stoller, K. M. Reiser, P. M. Celliers, and A. M. Rubenchik, "Polarization-modulated second harmonic generation in collagen," Biophys. J. 82, 3330-3342 (2002). (Pubitemid 34547675)
15. A. T. Yeh, B. Choi, J. S. Nelson, and B. J. Tromberg, "Reversible dissociation of collagen in tissues," J. Invest. Dermatol. 121,13321335 (2003).
16. E. Bell, B. Ivarsson, and C. Merrill, "Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro," Proc. Natl. Acad. Sci. U.S.A. 76, 1274-1278 (1979). (Pubitemid 9143722)
17. W. G. Jung, B. Kao, K. M. Kelly, J. S. Nelson, and Z. Chen, "Optical coherence tomography for in vitro monitoring of wound healing after laser irradiation," IEEE J. Sel. Top. Quantum Electron. 9, 222-226 (2003).
18. S. Huang, A. A. Heikal, and W. W. Webb, "Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein," Biophys. J. 82, 2811-2825 (2002). (Pubitemid 34441317)
19. E. Beaurepaire, L. Moreaux, F. Amblard, and J. Mertz, "Combined scanning optical coherence and two-photon-excited fluorescence microscopy," Opt. Lett. 24, 969-971 (1999). (Pubitemid 129308282)
20. Y. Zhao, Z. Chen, C. Saxer, S. Xiang, J. F. de Boer, and J. S. Nelson, "Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity," Opt. Lett. 25, 114-116 (2000).
21. B. H. Park, M. C. Pierce, B. Cense, and J. F. de Boer, "Real-time multi-functional optical coherence tomography," Opt. Express 11, 782-793 (2003).