Mechanisms of axonal loss and neuronal dysfunction in MS

Advanced Studies in Medicine

Volumn 4, Issue 4 B, 2004, Pages

  Trapp, Bruce D ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN CORTEX LESION; CONFERENCE PAPER; DEMYELINATING DISEASE; DISEASE COURSE; HUMAN; INFLAMMATION; MULTIPLE SCLEROSIS; NERVE CELL DEGENERATION; NERVE FIBER DEGENERATION; NERVE FIBER TRANSECTION; RELAPSE; REMISSION; SPINAL CORD ATROPHY;

EID: 2442692880     PISSN: 15303004     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (7)

1. Bjartmar C, Trapp BD. Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox Res. 2003;5(1-2):157-164.
2. Trapp BD, Peterson J, Ransohoff RM, Rudick R, Mork S, Bo L. Axonal transection in the lesions of multiple sclerosis. N Engl J Med. 1998;338(5):278-285.
3. Bjartmar C, Kidd G, Mork S, Rudick R, Trapp BD. Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients. Ann Neurol. 2000;48(6):893-901.
4. Peterson JW, Bo L, Mork S, Chang A, Trapp BD. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol. 2001;50(3):389-400.
5. Bo L, Vedeler CA, Nyland HI, Trapp BD, Mork SJ. Subpial demyelination in the cerebral cortex of multiple sclerosis patients. J Neuropothol Exp Neurol. 2003;62(7):723-732.
6. Montag D, Giese KP, Bartsch U, et al. Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin. Neuron. 1994;13(1):229-246.
7. Confavreux C, Vukusic S, Moreau T, Adeleine P. Relapses and progression of disability in multiple sclerosis. N Engl J Med. 2000;343(20):1430-1438.