The role of the angiopoietins in tumour angiogenesis

Growth Factors

Volumn 22, Issue 1, 2004, Pages 1-11

  Plank, Mike J ^a   Sleeman, B D ^a   Jones, P F ^b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Angiogenesis; Angiopoietins; Regression; Vascular quiescence

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOPOIETIN; VASCULOTROPIN;

ARTICLE; CANCER REGRESSION; MATHEMATICAL MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; QUALITATIVE ANALYSIS; REGULATORY MECHANISM; SOLID TUMOR; TUMOR GROWTH; TUMOR VASCULARIZATION;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANGIOPOIETINS; ANIMALS; ENDOTHELIAL CELLS; HUMANS; KINETICS; MODELS, STATISTICAL; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 2442692715     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.1080/08977190310001643218     Document Type: Article

References (42)

1. Acker, T., Beck, H. and Plate, K.H. (2001) "Cell type specific expression of vascular endothelial growth factor and angiopoietin-1 and -2 suggests an important role of astrocytes in cerebellar vascularisation", Mechanisms Dev. 108, 45-57.
2. Anderson, A.R.A. and Chaplain, M.A.J. (1998) "Continuous and discrete mathematical models of tumour-induced angiogenesis", Bull. Math. Biol. 60, 857-900.
3. Arakelyan, L., Vainstein, V. and Agur, Z. (2003a) "A computer algorithm describing the process of vessel formation and maturation, and its use for predicting the effects of anti-angiogenic and anti-maturation therapy on vascular tumour growth", Angiogenesis 5.
4. Arakelyan, L., Merbl, Y., Daugulis, P., Ginosar, Y., Vainstein, V., Selitser, V., Kogan, Y., Harpak, H. and Agur, Z. (2003b) "Multi-scale analysis of angiogenic dynamics and therapy", In: Preziosi, L., ed, Cancer modelling and simulation, (CRC Press, London), pp. 185-220.
5. Ashara, T., Chen, D., Takahashi, T., Fujikawa, K., Kearney, M., Magner, M., Yancopoulos, G.D. and Isner, J.M. (1998) "Tie-2 receptor ligands, angiopoietin 1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularisation", Circ. Res. 83, 233-240.
6. Ausprunk, D.H. and Folkman, J. (1977) "Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumour angiogenesis", Microvasc. Res. 14, 53-65.
7. Balding, D. and McElwain, D.L.S. (1985) "Mathematical modelling of tumour-induced capillary growth", J. Theor. Biol. 114, 53-73.
8. Beck, H., Acker, T., Wiessner, C., Allegrini, P.R. and Plate, K.H. (2000) "Expression of angiopoietin-1, angiopoietin-2 and Tie receptors after middle cerebral artery occlusion in the rat", Am. J. Path. 157, 1473-1483.
9. Byrne, H.M. and Chaplain, M.A.J. (1995) "Mathematical models for tumour angiogenesis: numerical simulations and nonlinear wave solutions", Bull. Math. Biol. 57, 461-486.
10. Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Van den Hoeck, A., Harpal, K., Eberhardt, C., De Clercq, C., Pawling, J. and Moons, L. (1996) "Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele", Nature 380, 435-439.
11. Chaplain, M.A.J., Giles, S.M., Sleeman, B.D. and Jarvis, R.J. (1995) "A mathematical model for tumour angiogenesis", J. Math. Biol. 33, 744-770.
12. Currie, M.J., Gunningham, S.P., Turner, K., Han, C., Scott, P.A.E., Robinson, B.A., Chong, W., Harris, A.L. and Fox, S.B. (2002) "Expression of the angiopoietins and their receptor Tie-2 in human renal clear cell carcinomas; regulation by the von Hippel-Landau gene and hypoxia", J. Path. 198, 502-510.
13. Davis, S., Aldrich, T.H., Jones, P.F., Acheson, A., Compton, D.L., Jain, V., Ryan, T.E., Bruno, J., Radziejewski, C., Maisonpierre, P.C. and Yancopoulos, G.D. (1996) "Isolation of angiopoietin-1, a ligand for the Tie-2 receptor, by secretion-trap expression cloning" , Cell 87, 1161-1169.
14. Folkman, J. (1971) "Tumour angiogenesis: therapeutic implications", N. Engl. J. Med. 285, 1192-1186.
15. Gale, N.W., Thurston, G., Hackett, S.F., Renard, R., Wang, Q., McClain, J., Martin, C., Witte, C., Witte, M.H., Jackson, D., Suri, C., Campochiaro, P.A., Wiegand, S.J. and Yancopoulos, G.D. (2002) "Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning and only the latter role is rescued by angiopoietin-1", Dev. Cell 3, 411-423.
16. Hackett, S.F., Ozaki, H., Strauss, R.W., Wahlin, K., Suri, C., Maisonpierre, P., Yancopoulos, G. and Campochiaro, P.A. (2000) "Angiopoietin-2 expression in the retina: upregulation during physiologic and pathologic neovascularisation", J. Cell Physiol. 184, 275-284.
17. Han, Z.C. and Liu, Y. (1999) "Angiogenesis: state of the art", Int. J. Haematol. 70, 68-82.
18. Harfouche, R., Hassessian, H.M., Guo, Y., Faivre, V., Srikant, C.B., Yancopoulos, G.D. and Hussain, S.N.A. (2002) " Mechanisms which mediate the antiapoptotic effects of angiopoiefin-1 on endothelial cells", Microvasc. Res. 64, 135-147.
19. Jones, P.F. (1997) "Tied up (or down?) with angiopoietins", Angiogenesis 1, 38-44.
20. Joussen, A.M., Poulaki, V., Tsujikawa, A., Qin, W., Qaum, T., Xu, Q., Moromizato, Y., Bursell, S., Wiegand, S.J., Rudge, J., Ioffe, E., Yancopoulos, G.D. and Adamis, A.P. (2002) "Suppression of diabetic retinopathy with angiopoietin-1", Am. J. Path. 160, 1683-1693.
21. Klagsbrun, M. and D'Amore, P.A. (1996) "Vascular endothelial growth factor and its receptors", Cytokine Growth Fact. Rev. 7, 259-270.
22. Levine, H.A., Sleeman, B.D. and Nilsen-Hamilton, M. (2000) "A mathematical model of the roles of pericytes and macrophages in the initiation of angiogenesis: I. the role of protease inhibitors in preventing angiogenesis", Math. Biosci. 168, 77-115.
23. Levine, H.A., Pamuk, S., Sleeman, B.D. and Nilsen-Hamilton, M. (2001) "A mathematical model of capillary formation and development in tumour angiogenesis: penetration into the stroma", Bull. Math. Biol. 63, 801-863.
24. Lobov, I.B., Brooks, P.C. and Lang, R.A. (2002) "Angiopoietin-2 displays vascular endothelial growth factor-dependent modulation of capillary structure and endothelial cell survival in vivo", Proc. Natl Acad. Sci. USA 99, 11205-11210.
25. Maisonpierre, P.C., Suri, C., Jones, P.F., Bartunkova, S., Wiegand, S.J., Radziejewski, C., Compton, D., McClain, J., Aldrich, T.H., Papandopoulos, N., Daly, T.J., Davis, S. and Sato, T.N. (1997) "Angiopoietin-2, a natural antagonist for Tie-2 that disrupts in vivo angiogenesis", Science 277, 55-60.
26. Oh, H., Takagi, H., Suzuma, K., Otani, A., Matsumura, M. and Honda, Y. (1999) "Hypoxia and vascular endothelial growth factor selectively upregulate angiopoietin-2 in bovine microvascular endothelial cells", J. Biol. Chem. 274, 15732-15739.
27. Othmer, H.G. and Stevens, A. (1997) "Aggregation, blowup and collapse: the ABC's of taxis and reinforced random walks", SIAM J. Appl. Math. 57, 1044-1081.
28. Papetti, M. and Herman, I.M. (2002) "Mechanisms of normal and tumour-derived angiogenesis", Am. J. Physiol. Cell Physiol. 282, C947-C970.
29. Paweletz, N. and Kneirim, M. (1989) "Tumour related angiogenesis", Crit. Rev. Oncol. Haematol. 9, 197-242.
30. Plank, M.J. and Sleeman, B.D. (2003) "A reinforced random walk model of tumour angiogenesis and anti-angiogenic strategies", IMA J. Math. Med. Biol. 20, 135-181.
31. Plank, M.J., Sleeman, B.D. and Jones, P.F. (2003) "A mathematical model of tumour angiogenesis regulated by vascular endothelial growth factor and the angiopoietins", J. Theor. Biol., submitted.
32. Sleeman, B.D. and Wallis, I.P. (2002) "Tumour induced angiogenesis as a reinforced random walk: modelling capillary network formation without endothelial cell proliferation", J. Math. Comp. Model. 36, 339-358.
33. Stokes, C.L. and Lauffenburger, D.A. (1991) "Analysis of the roles of microvessel endothelial cell random motility and chemotaxis in angiogenesis", J. Theor. Biol. 152, 377-403.
34. Sundberg, C., Kowanetz, M., Brown, L.F., Detmar, M. and Dvorak, H.F. (2002) "Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo", Lab. Invest. 82, 387-401.
35. Suri, C., Jones, P.F., Patan, S., Bartunkova, S., Maisonpierre, P.C., Davis, S., Sato, T.N. and Yancopoulos, G.D. (1996) "Requisite role of angiopoietin-1, a ligand for the Tie-2 receptor, during embryonic angiogenesis", Cell 87, 1171-1180.
36. Thurston, G., Rudge, J.S., Ioffe, E., Zhou, H., Ross, L., Croll, S.D., Glazer, N., Holash, J., McDonald, D.M. and Yancopoulos, G.D. (2000) "Angiopoietin-1 protects the adult vasculature against plasma leakage", Nat. Med. 6, 460-463.
37. Uemura, A., Ogawa, M., Hirashima, M., Fujiwara, T., Koyama, S., Takagi, H., Honda, Y, Wiegand, S.J., Yancopoulos, G.D. and Nishikawa, S.I. (2002) "Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells", J. Clin. Invest. 110, 1619-1628.
38. Unemori, E.N., Ferrara, N., Bauer, E.A. and Amento, E.P. (1992) "Vascular endothelial growth factor induces interstital collagenase expression in human endothelial cells", J. Cell Physiol. 153, 557-562.
39. Vajkoczy, P., Farhadi, M., Gaumann, A., Heidenreich, R., Erber, R., Wunder, A., Tonn, J.C., Menger, M.D. and Breier, G. (2002) "Microtumour growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2 and angiopoietin-2", J. Clin. Invest. 109, 777-785.
40. Witzenbichler, B., Maisonpierre, P.C., Jones, P., Yancopoulos, G.D. and Isner, J.M. (1998) "Chemotactic properties of angiopoietin-1 and -2, ligands for the endothelial-specific receptor tyrosine kinase Tie-2", J. Biol. Chem. 273, 18514-18521.
41. Yancopoulos, G.D., Davis, S., Gale, N.W., Rudge, J.S., Wiegand, S.J. and Holash, J. (2000) "Vascular-specific growth factors and blood vessel formation", Nature 407, 242-249.
42. Zagzag, D., Hooper, A., Friedlander, D.R., Chan, W., Holash, J., Wiegand, S.J., Yancopoulos, G.D. and Grumet, M. (1999) "In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumour angiogenesis", Exp. Neurol. 159, 391-400.