Activation and inhibition of cyclin-dependent kinase-2 by phosphorylation; a molecular dynamics study reveals the functional importance of the glycine-rich loop

Protein Science

Volumn 13, Issue 6, 2004, Pages 1449-1457

  Bártová, Iveta ^a   Otyepka, Michal ^b   Kříž, Zdeněk ^a   Koča, Jaroslav ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

^b PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

CDK regulation; Cell cycle; Phosphorylated tyrosine; Threonine

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIN A; CYCLIN DEPENDENT KINASE 2; GLYCINE; THREONINE; TYROSINE;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; SIMULATION;

CDC2-CDC28 KINASES; CYCLIN-DEPENDENT KINASE 2; ENZYME ACTIVATION; GLYCINE; MODELS, MOLECULAR; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 2442667660     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.03578504     Document Type: Article

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