Entrainment pattern between sympathetic and phrenic nerve activities in the Sprague-Dawley rat: Hypoxia-evoked sympathetic activity during expiration

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 286, Issue 6 55-6, 2004, Pages

  Dick, Thomas E ^a   Hsieh, Y H ^a   Morrison, Shaun ^b   Coles, Sharon K ^c   Prabhakar, Nanduri ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF SOUTH DAKOTA   (United States)

Author keywords

Chemoreflex; Hypoxic ventilatory response; Neural control of breathing; Neural control of sympathetic nerve activity

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING MECHANICS; CALCULATION; CONTROLLED STUDY; CYCLE TRIGGERED AVERAGE; EXPIRATORY FLOW; HYPOXIA; INSPIRATORY CAPACITY; MALE; NERVE CONDUCTION; NEUROMODULATION; NONHUMAN; PARAMETER; PHRENIC NERVE; PRIORITY JOURNAL; RAT; RAT STRAIN; SPLANCHNIC NERVE; SYMPATHETIC NERVE; SYMPATHETIC TONE;

ANIMALS; ANOXIA; MALE; MEDULLA OBLONGATA; NEURONAL PLASTICITY; NEURONS; PHRENIC NERVE; PONS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; RESPIRATORY MECHANICS; SYMPATHETIC NERVOUS SYSTEM; THORACOTOMY; VAGOTOMY;

EID: 2442665484     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00485.2003     Document Type: Article

References (50)

1. Bachoo M and Polosa C. Properties of the inspiration-related activity of sympathetic preganglionic neurones of the cervical trunk in the cat. J Physiol 385: 545-564, 1987.
2. Bainton C, Richter DW, Seller H, Ballantyne D, and Klein J. Respiratory modulation of sympathetic activity. J Auton Nerv Syst 12: 77-90, 1985.
3. Byrum CE and Guyenet PG. Afferent and efferent connections of the A5 noradrenergic cell group in the rat. J Comp Neurol 261: 529-542, 1987.
4. Chamberlin NL and Saper CB. Topographic organization of respiratory responses to glutamate microstimulation of the parabrachial nucleus in the rat. J Neurosci 14: 6500-6510, 1994.
5. Chang HS, Staras K, Smith JE, and Gilbey MP. Sympathetic neuronal oscillators are capable of dynamic synchronization. J Neurosci 19: 3183-3197, 1999.
6. Chang HS, Staras K, and Gilbey MP. Multiple oscillators provide metastability in rhythm generation. J Neurosci 20: 5135-5143, 2000.
7. Coles SK and Dick TE. Neurones in the ventrolateral pons are required for post-hypoxic frequency decline in rats. J Physiol 497: 79-94, 1996.
8. Collins DR and Gilbey MP. Cutaneous sympathetic motor rhythms in the decerebrate rat. Neuroscience 117: 981-989, 2003.
9. Czyzyk-Krzeska MF and Trzebski A. Respiratory-related discharge pattern of sympathetic nerve activity in the spontaneously hypertensive rat. J Physiol 426: 355-368, 1990.
10. Darnall RA and Guyenet P. Respiratory modulation of pre- and post-ganglionic lumbar vasomotor sympathetic neurons in the rat. Neurosci Lett 119: 148-152, 1990.
11. Dick TE and Coles SK. Ventrolateral pons mediates short-term depression of respiratory frequency after brief hypoxia. Respir Physiol 121: 87-100, 2000.
12. Gilbey MP. Multiple oscillators, dynamic synchronization and sympathetic control. Clin Exp Pharmacol Physiol 28: 130-137, 2001.
13. Guyenet PG. Neural structures that mediate sympathoexcitation during hypoxia. Respir Physiol 121: 147-162, 2001.
14. Guyenet PG, Koshiya N, Huangfu D, Verberne AJ, and Riley TA. Central respiratory control of A5 and A6 pontine noradrenergic neurons. Am J Physiol Regul Integr Comp Physiol 264: R1035-R1044, 1993.
15. Haselton JR and Guyenet PG. Central respiratory modulation of medullary sympathoexcitatory neurons in rat. Am J Physiol Regul Integr Comp Physiol 256: R739-R750, 1989.
16. Hayward LF and Felder RB. Lateral parabrachial nucleus modulates baroreflex regulation of sympathetic nerve activity. Am J Physiol Regul Integr Comp Physiol 274: R1274-R1282, 1998.
17. Hirooka Y, Polson JW, Potts PD, and Dampney RAL. Hypoxia-induced FOS expression in neurons projecting to the pressor region in the rostral ventrolateral medulla. Neuroscience 80: 1209-1224, 1997.
18. Huangfu DH, Koshiya N, and Guyenet PG. A5 noradrenergic unit activity and sympathetic nerve discharge in rats. Am J Physiol Regul Integr Comp Physiol 261: R393-R402, 1991,
19. Jodkowski JS, Coles SK, and Dick TE. Prolongation in expiration evoked from ventrolateral pons of adult rats. J Appl Physiol 82: 377-381, 1997.
20. Koshiya N and Guyenet PG. Tonic sympathetic chemoreflex after blockade of respiratory rhythmogenesis in the rat. J Physiol 491: 859-869, 1996.
21. Koshiya N and Guyenet PG. Sympatholytic effect of clonidine depends on the respiratory phase in rat splanchnic nerve. J Auton Nerv Syst 53: 82-86, 1995.
22. Koshiya N and Guyenet PG. A5 noradrenergic neurons and the carotid sympathetic chemoreflex. Am J Physiol Regul Integr Comp Physiol 267: R519-R526, 1994.
23. Koshiya N and Guyenet PG. Role of the pons in the carotid sympathetic chemoreflex. Am J Physiol Regul Integr Comp Physiol 267: R508-R518, 1994.
24. Lara JP, Parkes MJ, Silva-Carvhalo L, Izzo P, Dawid-Milner MS, and Spyer KM. Cardiovascular and respiratory effects of stimulation of cell bodies of the parabrachial nuclei in the anaesthetized rat. J Physiol 477: 321-329, 1994.
25. Malpas SC. Neural influences on cardiovascular variability: possibilities and pitfalls. Am J Physiol Heart Circ Physiol 282: H6-H20, 2002.
26. Malpas SC. The rhythmicity of sympathetic nerve activity. Prog Neurobiol 56: 65-96, 1998.
27. Marshall JM. Peripheral chemoreceptors and cardiovascular regulation. Physiol Rev 64: 543-594, 1994.
28. Melton JE, Kadia SC, Yu QP, Neubauer JA, and Edelman NH. Respiratory and sympathetic activity during recovery from hypoxic depression and gasping in cats. J Appl Physiol 80: 1940-1948, 1996.
29. Mifflin SW and Felder RB. Synaptic mechanisms regulating cardiovascular afferent inputs to solitary tract nucleus. Am J Physiol Heart Circ Physiol 259: H653-H661, 1990.
30. Miyawaki T, Goodchild AK, and Pilowsky PM. Evidence for a tonic GABA-ergic inhibition of excitatory respiratory-related afferents to presympathetic neurons in the rostral ventrolateral medulla. Brain Res 924: 56-62, 2002.
31. Morgan BJ, Crabtree DC, Palta M, and Skatrud JB. Combined hypoxia and hypercapnia evokes long-lasting sympathetic activation in humans. J Appl Physiol 79: 205-213, 1995.
32. Morrison SF. Respiratory modulation of sympathetic nerve activity: effect of MK-801. Am J Physiol Regul Integr Comp Physiol 270: R645-R651, 1996.
33. Morrison SF, Milner TA, and Reis DJ. Reticulospinal vasomotor neurons of the rat rostral ventrolateral medulla: relationship to sympathetic nerve activity and the C1 adrenergic cell group. J Neurosci 8: 1286-1301, 1988.
34. Netick A and Orem J. Erroneous classification of neuronal activity by the respiratory modulation index. Neurosci Lett 21: 301-306, 1981.
35. Pilowsky P, Llewellyn-Smith IJ, Lipski J, Minson J, Arnolda L, and Chalmers J. Projections from inspiratory neurons of the ventral respiratory group to the subretrofacial nucleus of the cat. Brain Res 633: 63-71, 1994.
36. Pilowsky P, Arnolda L, Chalmers J, Llewellyn-Smith I, Minson J, Miyawaki T, and Sun QJ. Respiratory inputs to central cardiovascular neurons. Ann NY Acad Sci 783: 64-70, 1996.
37. Poon CS and Siniaia MS. Plasticity of cardiorespiratory neural processing: classification and computational functions. Respir Physiol 122: 83-109, 2000.
38. Poon CS, Siniaia MS, Young DL, and Eldridge FL. Short-term potentiation of carotid chemoreflex: an NMDAR-dependent neural integrator. Neuroreport 10: 2261-2265, 1999.
39. Powell FL, Milsom WK, and Mitchell GS. Time domains of the hypoxic ventilatory response. Respir Physiol 112: 123-134, 1998.
40. Richter DW and Spyer KM. Cardiorespiratory control. In: Central Regulation of Autonomic Function, edited by Loewy AD and KM Spyer. New York: Oxford Univ. Press, 1990, p. 189-207.
41. Solomon IC, Edelman NH, and Neubauer JA. Pre-Botzinger Complex functions as a central hypoxia chemosensor for respiration in vivo. J Neurophysiol 83: 2854-2868, 2000.
42. Strohl KP, Thomas AJ, St Jean P, Schlenker EH, Koletsky RJ, and Schork NJ. Ventilation and metabolism among rat strains. J Appl Physiol 82: 317-323, 1997.
43. Sun MK and Reis DJ. Hypoxia selectively excites vasomotor neurons of rostral ventrolateral medulla in rats. Am J Physiol Regul Integr Comp Physiol 266: R245-R256, 1994.
44. Sun MK and Reis DJ. Decerebration does not alter hypoxic sympathoexcitatory responses in rats. J Auton Nerv Syst 53: 77-81, 1995.
45. Taylor EW, Jordan D, and Coote JH. Central control of the cardiovascular and respiratory systems and their interactions in vertebrates. Physiol Rev 79: 855-916, 1999.
46. Van Lunteren E, Mitra J, Prabhakar NR, Haxhiu MA, and Cherniack NS. Ventral medullary surface inputs to cervical sympathetic respiratory oscillations. Am J Physiol Regul Integr Comp Physiol 252: R1032-R1038, 1987.
47. Xie A, Skatrud JB, Puleo DS, and Morgan BJ. Exposure to hypoxia produces long-lasting sympathetic activation in humans. J Appl Physiol 91: 1555-1562, 2001.
48. Zhong S, Zhou SY, Gebber GL, Barman SM. Coupled oscillators account for the slow rhythms in sympathetic nerve discharge and phrenic nerve activity. Am J Physiol Regul Integr Comp Physiol 272: R1314-R1324, 1997.
49. Zhou SY and Gilbey MP. Respiratory-related activity of lower thoracic and upper lumbar sympathetic preganglionic neurones in the rat. J Physiol 451: 631-642, 1992.
50. Zhou SY, Gebber GL, Zhong S, and Barman SM. Pathways involved in synchronization of sympathetic nerve discharge to lung inflation. Brain Res 931: 107-116, 2002.