Four potassium channel mutations account for 73% of the genetic spectrum underlying long-QT syndrome (LQTS) and provide evidence for a strong founder effect in Finland

Annals of Medicine

Volumn 36, Issue SUPPL. 1, 2004, Pages 53-63

  Fodstad, Heidi ^a,b   Swan, Heikki ^b   Laitinen, Päivi ^a,b   Piippo, Kirsi ^a,b   Paavonen, Kristian ^a,b   Viitasalo, Matti ^b   Toivonen, Lauri ^b   Kontula, Kimmo ^a,b  

^a BIOMEDICUM HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Arrhythmia; Founder gene; Ion channel; Long QT syndrome; Mutation

Indexed keywords

DNA; POTASSIUM CHANNEL;

CONFERENCE PAPER; DENATURATION; DNA SEQUENCE; FINLAND; GENE MUTATION; GENETIC IDENTIFICATION; HUMAN; INFORMATION PROCESSING; LONG QT SYNDROME; MEDICAL RESEARCH; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCREENING TEST;

CATION TRANSPORT PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA MUTATIONAL ANALYSIS; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; FINLAND; FOUNDER EFFECT; GENETIC SCREENING; HUMANS; KCNQ POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; LONG QT SYNDROME; MALE; MIDDLE AGED; MUTATION; PHENOTYPE; POLYMORPHISM, GENETIC; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SODIUM CHANNELS;

EID: 2442657712     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.1080/17431380410032689     Document Type: Conference Paper

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