Comparative metabolism of the aza polynuclear aromatic hydrocarbon dibenz[a,h]acridine by recombinant human and rat cytochrome P450s

Chemical Research in Toxicology

Volumn 17, Issue 5, 2004, Pages 672-678

  Yuan, Zhi Xin ^a   Kumar, Subodh ^a   Sikka, Harish C ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIDINE DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450 3A4; DIBENZ[A,H]ACRIDINE; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; CHEMICAL BOND; CHEMICAL STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID SCINTILLATION COUNTING; METABOLIC ACTIVATION; NONHUMAN; RAT; STEREOCHEMISTRY;

ACRIDINES; ANIMALS; AZA COMPOUNDS; BIOTRANSFORMATION; CARBON RADIOISOTOPES; CARCINOGENS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; EPOXY COMPOUNDS; HUMANS; MICROSOMES, LIVER; NITROGEN; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; RECOMBINANT PROTEINS; STEREOISOMERISM;

EID: 2442656592     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx049979i     Document Type: Article

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