Adeno-associated viral vector-mediated ApoE expression in Alzheimer's disease mice: Low CNS immune response, long-term expression, and astrocyte specificity

Frontiers in Bioscience

Volumn 9, Issue , 2004, Pages 1540-1546

  Feng, Xuan ^a,b   Eide, Fernette F ^a   Jiang, Hong ^a   Reder, Anthony T ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Campus Box 8069   (United States)

Author keywords

AAV vector; Adenoviral vector; Alzheimer's disease mouse model; ApoE; CNS; Gene expression; Gene therapy; GFAP; Immune response; Review

Indexed keywords

APOLIPOPROTEIN E; CD45 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; GLIAL FIBRILLARY ACIDIC PROTEIN; HYBRID PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ASTROCYTE; CELL SPECIFICITY; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; GENE EXPRESSION; IMMUNE SYSTEM; MOUSE; NONHUMAN; PARVOVIRUS VECTOR; PROTEIN EXPRESSION; REPORTER GENE; REVIEW; VIRUS VECTOR; ADENO ASSOCIATED VIRUS; ALLELE; ANIMAL; ARTICLE; C57BL MOUSE; CYTOLOGY; GENE VECTOR; GENETICS; HIPPOCAMPUS; HUMAN; IMMUNOLOGY; KINETICS; METABOLISM;

ADENO-ASSOCIATED VIRUS; ADENOVIRIDAE; ANIMALIA; PARVOVIRUS;

ALLELES; ALZHEIMER DISEASE; ANIMALS; APOLIPOPROTEINS E; ASTROCYTES; CENTRAL NERVOUS SYSTEM; DEPENDOVIRUS; GENE EXPRESSION; GENETIC VECTORS; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HUMANS; KINETICS; MICE; MICE, INBRED C57BL; RECOMBINANT FUSION PROTEINS;

EID: 2442646815     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1323     Document Type: Review

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