Interactions between lipopolysaccharide and the intestinal epithelium

Journal of the American Veterinary Medical Association

Volumn 224, Issue 9, 2004, Pages 1446-1452

  Tomlinson, Julia E ^a   Blikslager, Anthony T ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE;

ENDOTOXEMIA; INTESTINE EPITHELIUM; INTESTINE ISCHEMIA; MEMBRANE PERMEABILITY; MOLECULAR INTERACTION; NONHUMAN; REVIEW; SEPTIC SHOCK;

ANIMALS; CHEMOTAXIS; ENDOTOXEMIA; EPITHELIAL CELLS; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES;

EID: 2442581583     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.2004.224.1446     Document Type: Review

References (61)

1. Moore JN, White NA, Berg JN, et al. Endotoxemia following experimental intestinal strangulation obstruction in ponies. Can J Comp Med 1981;45:330-332.
2. King JN, Gerring EL. Detection of endotoxemia in cases of equine colic. Vet Rec 1988;123:269-271.
3. Meyers K, Reed S, Keck M, et al. Circulating endotoxin-like substance(s) and altered hemostasis in horses with gastrointestinal disorders: an interim report. Am J Vet Res 1982;43:2233-2238.
4. Shuster R, Traub-Dargatz J, Baxter G. Survey of diplomates of the American College of Veterinary Internal Medicine and the American College of Veterinary Surgeons regarding clinical aspects and treatment of endotoxemia in horses. J Am Vet Mod Assoc 1997; 210:87-92.
5. Dabareiner RM, White NA, Donaldson LL. Effects of intraluminal distention and decompression on microvascular permeability and hemodynamics of the equine jejunum. Am J Vet Res 2001; 62:225-236.
6. Gerard MP, Blikslager AT, Roberts MC, et al. The characteristics of intestinal injury peripheral to strangulating obstruction lesions in the equine small intestine. Equine Vet J 1999;31:331-335.
7. Morris DD. Endotoxemia in horses. A review of cellular and humoral mediators involved in its pathogenesis. J Vet Intern Med 1991;5:167-181.
8. Martich GD, Boujoukos AJ, Suffredini AF. Response of man to endotoxin. Immunobiology 1993;187:403-416.
9. Hershberg RM. The epithelial cell. cytoskeleton and intracellular trafficking V. Polarized compartmentalization of antigen processing and Toll-like receptor signaling in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2002;283:G833-G839.
10. Moore JN, Garner HE, Berg JN, et al. Intracecal endotoxin and lactate during the onset of equine laminitis: a preliminary report. Am J Vet Res 1979;40:722-723.
11. Biancone L, Monteleone I, Del Vecchio Blanco G, et al. Resident bacterial flora and immune system. Dig Liver Dis 2002; 34(suppl 2):S37-S43.
12. Jacob AI, Goldberg PK, Bloom N, et al. Endotoxin and bacteria in portal blood. Gastroenterology 1977;72:1268-1270.
13. Ruiter DJ, Van Der Maulen J, Brouwer A, et al. Uptake by liver cells of endotoxin following its venous injection. Lab Invest 1981;45:38-45.
14. Morrison DC, Rudbach JA. Endotoxin-cell-membrane interactions leading to transmembrane signaling. Contemp Top Mol Immunol 1981;8:187-218.
15. Jackson SK, James PE, Rowlands CC, et al. Binding of endotoxin to macrophages: interactions of spin labeled saccharide residues. Biochim Biophys Acta 1992;1135:165-170.
16. Schletter J, Heine K, Ulmer AJ, et al. Molecular mechanisms of endotoxin activity. Arch Microbiol 1995;164:383-389.
17. Reitschel ET, Kirikae T, Schade FU, et al. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J 1994;8:217-225.
18. 125I-lipopolysaccharide. Infect Immun 1992;60:5145-5152.
19. Israelachvili JN. Aggregation of amphiphilic molecules into micelles, bilayers, vesicles and biological membranes. In: Intermolecular and surface forces. 2nd ed. London: Academic Press Inc, 1991;366-393.
20. Takayama Y, Mitchell DH, Din ZZ, et al. Monomeric Re lipopolysaccharide from Escherischia coli is more active than the aggregated form in the Limulus amoebacyte lysate assay and in inducing egr-1 mRNA in murine peritoneal macrophages. J Biol Chem 1994;269:2241-2244.
21. Weidemann B, Brade H, Rietschel ET, et al. Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures. Infect Immun 1994;62:4709-4715.
22. Antal-Szalmas P. Evaluation of CD14 in host defense. Eur J Clin Invest 2000;30:167-179.
23. Fearns C, Ulevitch RJ. Effect of recombinant interleukin-1beta on murine CD14 gene expression in vivo. Shock 1998;9: 157-163.
24. Bazil V, Horejsi V, Baudys M, et al. Biochemical characterization of a soluble form of the 53-kDa monocyte surface antigen. Eur J Immunol 1986;16:1583-1589.
25. Landmann R, Zimmerli W, Sansano S, et al. Increased circulating soluble CD14 is associated with high mortality in gram-negative septic shock. J Infect Dis 1995;171:639-644.
26. Frey EA, Miller DS, Jahr TG, et al. Soluble CD14 participates in the response of cells to lipopolysaccharide. J Exp Med 1992; 176:1665-1671.
27. Hailman E, Lichtenstein HS, Wurfel MM, et al. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J Exp Med 1994;179:269-277.
28. Vreugdenhil ACE, Snoek AMP, Greve JWM, et al. Lipopolysaccharide-binding protein is vectorially secreted and transported by cultured intestinal epithelial cells and is present in the intestinal mucus of mice. J Immunol 2000;165:4561-4566.
29. Bochsler PN, Yang Z, Murphy CL, et al. Purification of lipopolysaccharide-binding protein from bovine serum. Vet Immunol Immunopathol 1996;51:303-314.
30. Lamping N, Dettmer R, Schroder NW et al. LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria. J Clin Invest 1998;101:2065-2071.
31. Ulevitch RJ, Tobias PS. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Ann Rev Immunol 1995;13: 437-457.
32. Aderem A, Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature 2000;406:782-787.
33. Ulevitch RJ, Tobias PS. Recognition of endotoxin by cells leading to transmembrane signaling. Curr Opin Immunol 1994;6:125-130.
34. Anderson KV. Toll signaling pathways in the innate immune response. Curr Opin Immunol 2000;12:13-19.
35. Brighthill HD, Modlin RL. Toll-like receptors: molecular mechanisms of the mammalian immune response. Immunology 2000; 101:1-10.
36. Medzhitov R, Preston-Hurlburt P, Janeway CA. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997;388:394-397.
37. Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282:2085-2088.
38. Monick MM, Powers L, Butler N, et al. Interaction of matrix with integrin receptors is required for optimal LPS-induced MAP kinase activation. Am J Physiol Lung Cell Mol Physiol 2002;283: L390-L402.
39. Underhill DM, Ozinsky A, Hajjar AM, et al. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 1999;401:811-815.
40. Shubing L, Gallo DJ, Green AM, et al. Role of Toll-like receptors in changes in gene expression and NF-IκB activation in mouse hepatocytes stimulated with lipolysaccharide. Infect Immun 2002;70:3433-3442.
41. Kitamura H, Kanehira K, Shiina T, et al. Bacterial lipopolysaccharide induces mRNA expression of an IκB MAIL through Toll-like receptor 4. J Vet Med Sci 2002;64:419-422.
42. Dziarski R, Wang Q, Miyake K, et al. MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to gram-positive and gram-negative bacteria and their cell wall components. J Immunol 2001;166:1938-1944.
43. Yang H, Young DW, Gusovsky F, et al. Cellular events mediated by lipopolysaccharide-stimulated Toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1. J Biol Chem 2000;27:20861-20866.
44. Eckmann L, Kagnoff ME. Cytokines in host defense against Salmonella. Microbes Infect 2001;3:1191-1200.
45. Abreu MT, Arnold ET, Thomas LS, et al. TLR4 and MD-2 expression is regulated by munune-mediated signals m human intestinal epithelial cells. J Biol Chem 2002;277:20431-20437.
46. Hausmann M, Kiessling S, Mestermann S, et al. Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation. Gastroenterology 2002;122:1987-2000.
47. Imaeda H. Yamamoto H, Takaki A, et al. In vivo response of neutrophils and epithelial cells to lipopolysaccharide injected into the monkey ileum. Histochem Cell Biol 2002;118:381-388.
48. Backheed F, Meijer T, Normark S, et al. TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14. Cell Microbiol 2002;4:493-501.
49. Suzuki M, Hisamatsu T, Podolsky D. Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex. Infect Immun 2003;71:3503-3511.
50. Hornef MW, Frisan T, Vandewalle A, et al. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med 2002;195: 559-570.
51. Garcia-del Portillo F, Stein MA, Finlay BB. Release of lipopolysaccharide from intracellular compartments containing Salmonella typhimurium to vesicles of the host epithelial cell. Infect Immun 1997;65:24-34.
52. Carmy G, Levy O, Futura GT, et al. Lipid mediator-induced expression of bactericidal/permeability increasing protein (BPI) in human mucosal epithelia. Proc Natl Acad Sci U S A 2002;99: 3902-3907.
53. Benoit R, Rowe S, Watkins SC, et al. Pure endotoxin does not pass across the epithelium in vitro. Shock 1998;10:43-48.
54. Osman NE, Westrom B, Karlsson B. Serosal but not mucosal endotoxin exposure increases intestinal permeability in vitro in the rat. Scan J Gastroenterol 1998;33:1170-1174.
55. Beatty WL, Sansonetti PJ. Role of lipopolysaccharide in signaling to subepithelial polymorphonuclear leukocytes. Infect Immun 1997;65:4395-4404.
56. Gathiram P, Wells MT, Raidoo D, et al. Changes in lipopolysaccharide concentrations in hepatic portal and systemic arterial plasma during intestinal ischemia in monkeys. Circ Shock 1989;27:103-109.
57. 2 have a synergistic role in rescuing epithelial barrier function in porcine ileum. J Clin Invest 1997;100:1928-1933.
58. Drewe J, Beglinger C, Fricker G. Effect of ischemia on intestinal permeability of lipopolysacchrides. Eur J Clin Invest 2001; 31:138-144.
59. 3 receptors in the rat ileum. Am J Physiol Gastrointest Liver Physiol 2003;284:G782-G788.
60. Ruemmele FM, Beaulieu JF, Dionne S, et al. Lipopolysaccharide modulation of normal enterocyte turnover by Toll-like receptors is mediated by endogenously produced tumor necrosis factor alpha. Gut 2002;51:842-848.
61. Moore JN, Morris DD. Endotoxemia and septicemia in horses: experimental and clinical correlates. J Am Vet Med Assoc 1992;200:1903-1914.