Mirtazapine improves alcohol detoxification

Journal of Psychopharmacology

Volumn 18, Issue 1, 2004, Pages 88-93

  Liappas, J ^a   Paparrigopoulos, T ^a   Malitas, P ^a   Tzavellas, E ^a   Christodoulou, G ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Alcohol; Anxiety; Depression; Detoxification; Mirtazapine

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; DIAZEPAM; MIRTAZAPINE; VITAMIN B COMPLEX;

ADULT; AGED; ALCOHOL ABUSE; ALCOHOLISM; ANXIETY DISORDER; ARTICLE; BEHAVIOR THERAPY; CLINICAL TRIAL; COGNITIVE THERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DETOXIFICATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT COMPLIANCE; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; PSYCHOTHERAPY; REMISSION; SINGLE BLIND PROCEDURE; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; ALCOHOLISM; ANTIDEPRESSIVE AGENTS, TRICYCLIC; COMBINED MODALITY THERAPY; FEMALE; HUMANS; MALE; MIANSERIN; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTHERAPY; SUBSTANCE WITHDRAWAL SYNDROME; TEMPERANCE; TREATMENT OUTCOME;

EID: 2442546713     PISSN: 02698811     EISSN: None     Source Type: Journal    
DOI: 10.1177/0269881104040241     Document Type: Article

References (34)

1. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders (DSM-IV), 4th edn. American Psychiatric Association, Washington, DC
2. Angelone S M, Bellini L, Di Bella D, Catalano M (1998) Effects of fluvoxamine and citalopram in maintaining abstinence in a sample of Italian detoxified alcoholics. Alcohol 33: 151-156
3. Balldin J, Berggren U, Engel J, Eriksson M, Hard E, Soderpalm B (1994) Effect of citalopram on alcohol intake in heavy drinkers. Alcohol Clin Exp Res 18: 1133-1136
4. Brown W E, Schuckit M A (1988) Changes in depression among abstinent alcoholics. J Stud Alcohol 49: 412-417
5. Brown S A, Irwin M, Schuckit M A (1991) Changes in anxiety among abstinent male alcoholics. J Stud Alcohol 52: 55-61
6. Brown S A, Inaba R K, Gillin C J, Schuckit M A, Stewart M A, Irwin M R (1995) Alcoholism and affective disorder: clinical course of depressive symptoms. Am J Psychiatry 152: 45-52
7. Cornelius J R, Salloum I M, Ehler J G, Jarrett P J, Cornelius M B, Perel J M, Thase M E, Black A (1997) Fluoxetine in depressed alcoholics: a double blind, placebo-controlled trial. Arch Gen Psychiatry 54: 700-705
8. de Boer T (1995) The effects of mirtazapine on central noradrenergic and serotonergic neurotransmission. Int Clin Psychopharmacol 10 (Suppl 4):19-23
9. Gorelick D A (1989) Serotonin uptake blockers and the treatment of alcoholism. Recent Dev Alcohol 7: 67-281
10. Grant B F, Harford T C (1995) Comorbidity between DSM-IV alcohol use' disorders and major depression: results of a national survey. Drug, Alcohol Depend 39: 197-206
11. Helzer J E, Przybeck T R (1988) The co-occurrence of alcoholism with other psychiatric disorders in the general population and its impact on treatment. J Stud Alcohol 49: 219-224
12. Hesselbrock M N, Meyer R E, Keener J J (1985) Psychopathology in hospitalized alcoholics. Arch Gen Psychiatry 42: 1050-1055
13. Hughes P H, Venulet J, Khant U, Medina Mora M E, Navaratnam V, Poshyachinda V, Rootman I, Salan R, Wadud K A (1980) Core data for epidemiological studies on nonmedical drug use (Offset Publication 56). Geneva: World Health Organization
14. Kasper S (1995) Clinical efficacy of mirtazapine: a review of meta-analyses of pooled data. Int Clin Psychopharmacol 10 (Suppl 4):25-35
15. Kessler R C, Crum R M, Warner L A, Nelson C B, Schulenberg J, Anthony J C (1997) Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey. Arch Gen Psychiatry 54: 313-321
16. Kranzler H R, Anton R F (1994) Implications of recent neuropsychopharmacologic research for understanding the etiology and development of alcoholism. J Consult Clin Psychol 62: 1116-1126
17. Kushner M G, Sher K J, Beitman B D (1990) The relation between alcohol problems and the anxiety disorders. Am J Psychiatry 147: 685-695
18. Le Marquand D, Pihl R O, Benkelfat C (1994) Serotonin and alcohol intake, abuse and dependence: clinical evidence. Biol Psychiatry 36: 326-337
19. Liappas J, Paparrigopoulos T, Tzavellas E, Christodoulou G (2002) Impact of alcohol detoxification on anxiety and depressive symptoms. Drug Alcohol Depend 68: 215-220
20. Liappas J, Paparrigopoulos T, Tzavellas E, Christodoulou G (2003) Alcohol detoxification and social anxiety symptoms: A preliminary study of the impact of mirtazapine administration. J Aff Disord 76: 279-284
21. Litten R Z, Allen J P (1998) Pharmacologic treatment of alcoholics with collateral depression: issues and future directions. Psychopharmacol Bull 34: 107-110
22. Litten R Z, Allen J, Fertig J (1996) Pharmacotherapies for alcohol problems: a review of research with focus on developments since 1991. Alcohol Clin Exp Res 20: 859-876
23. Mason B J, Kocsis J H, Ritvo E C, Cutler R B (1996) A double-blind, placebo-controlled trial of desipramine for primary alcohol dependence stratified on the presence or absence of major depression. JAMA 275: 761-767
24. McGrath P J, Nunes E V, Stewart J W, Goldman D, Agosti V, Ocepek-Welikson K, Quitkin FM (1996) Imipramine treatment of alcoholics with primary depression: a placebo-controlled clinical trial. Arch Gen Psychiatry 53: 232-240
25. Meyer R E (1989) Prospects for a rational pharmacotherapy of alcoholism. J Clin Psychiatry 50: 403-412
26. Montgomery S A (1995) Safety of mirtazapine: a review. Int Clin Neuropsychopharmacol 10 (Suppl 4): 37-45
27. Regier D A, Farmer M E, Rae D S, Locke B Z, Keith S J, Judd L L, Goodwin F K (1990) Comorbidity of mental disorders with alcohol and other drug abuse: results from the Epidemiologic Catchment Area (ECA) Study. JAMA 264: 2511-2518
28. Schaffer A, Naranjo C A (1998) Recommended drug treatment strategies for the alcoholic patient. Drugs 56: 571-585
29. Schuckit M A (1996) Recent developments in the pharmacotherapy of alcohol dependence. J Consult Clin Psychol 64: 669-676
30. Sitsen J M A, Zivkov M (1995) Mirtazapine: clinical profile. CNS Drugs 4 (Suppl1): 39-48
31. Swendsen J D, Merikangas K R, Canino G J, Kessler R C, Rubio-Stipec M, Angst J (1998) The comorbidity of alcoholism with anxiety and depressive disorders in four geographic communities. Compr Psychiatry 39: 176-184
32. Tabakoff B, Hoffman P L (1991) Neurochemical effects of alcohol. In Frances R J, Miller S I (eds), Clinical textbook of addictive disorders, pp. 501-525. Guilford Press, New York
33. Thevos A K, Johnston A L, Latham P K, Randall C L, Adinoff B, Malcolm R (1991) Symptoms of anxiety in inpatient alcoholics with and without DSM-III-R anxiety diagnoses. Alcohol Clin Exp Res 15: 102-105
34. World Health Organization (1990) Composite International Diagnostic Interview - CIDI, core version 1.0. Division of Mental Health, World Health Organization, Geneva