Recurrence of severe steroid dependency in cyclosporin A-treated childhood idiopathic nephrotic syndrome

Nephrology Dialysis Transplantation

Volumn 19, Issue 5, 2004, Pages 1136-1141

  Kemper, Markus J ^a,b   Kuwertz Broeking, Eberhard ^c   Bulla, Monika ^c   Mueller Wiefel, Dirk E ^b   Neuhaus, Thomas J ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Childhood; Cyclosporin A; Long term remission; Maintenance therapy; Steroid dependent nephrotic syndrome

Indexed keywords

CHLORAMBUCIL; CYCLOSPORIN A; LEVAMISOLE; PREDNISONE; STEROID;

ADOLESCENT; ADULT; ADULTHOOD; ARTICLE; BEHAVIOR DISORDER; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG SENSITIVITY; DRUG WITHDRAWAL; FEMALE; HUMAN; IDIOPATHIC DISEASE; INFANT; LONG TERM CARE; MAINTENANCE THERAPY; MALE; MOON FACE; NEPHROTIC SYNDROME; OBESITY; PRIORITY JOURNAL; RECURRENT DISEASE; REMISSION; RETROSPECTIVE STUDY; STRIA; TREATMENT FAILURE; TREATMENT OUTCOME;

ADRENAL CORTEX HORMONES; CHILD; CHILD, PRESCHOOL; CYCLOSPORINE; FOLLOW-UP STUDIES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; NEPHROTIC SYNDROME; RECURRENCE; SUBSTANCE-RELATED DISORDERS; TIME FACTORS;

EID: 2442539049     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/gfh066     Document Type: Article

References (21)

1. Clark AG, Barratt TM. Steroid-responsive nephrotic syndrome. In: Barratt TM, Avner ED, Harmon WE, eds. Pediatric Nephrology, 4th edn. Lippincott Williams & Wilkins, Baltimore; 1999: 731-748
2. Arbeitsgemeinschaft für Pädiatrische Nephrologie. Short versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Lancet 1988; 380-383
3. Ehrich JH, Brodehl J. Long versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Arbeitsgemeinschaft für Pädiatrische Nephrologie. Eur J Pediatr 1993; 152: 357-361
4. International Study of Kidney Disease in Children. The primary nephrotic syndrome in children. Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. J Pediatr 1981; 98: 561-564
5. Arbeitsgemeinschaft für Pädiatrische Nephrologie. Cyclophosphamide treatment of steroid dependent nephrotic syndrome: comparison of eight week with 12 week course. Arch Dis Child 1987; 62: 1102-1106
6. Ueda N, Kuno K, Ito S. Eight and 12 week courses of cyclophosphamide in nephrotic syndrome. Arch Dis Child 1990; 65: 1147-1150
7. Kemper MJ, Altrogge H, Ludwig K, Timmermann K, Müller-Wiefel DE. Unfavorable response to cyclophosphamide in steroid-dependent nephrotic syndrome. Pediatr Nephrol 2000; 14: 772-775
8. British Association for Paediatric Nephrology. Levamisole for corticosteroid-dependent nephrotic syndrome in childhood. Lancet 1991; 337: 1555-1557
9. Kemper MJ, Amon O, Timmermann K, Altrogge H, Müller-Wiefel DE. Frequently relapsing steroid-sensitive idiopathic nephrotic syndrome in children: its treatment with levamisole. Dtsch Med Wochenschr 1998; 123: 239-243
10. Hulton SA, Neuhaus TJ, Dillon MJ, Barratt TM. Long-term cyclosporin A treatment of minimal-change nephrotic syndrome of childhood. Pediatr Nephrol 1994; 8: 401-403
11. Brodehl J. The treatment of minimal change nephrotic syndrome: lessons learned from multicentre co-operative studies. Eur J Pediatr 1991; 150: 380-387
12. Niaudet P, Habib R. Cyclosporine in the treatment of idiopathic nephrosis. J Am Soc Nephrol 1994; 5: 1049-1056
13. Neuhaus TJ, Fay J, Dillon MJ, Trompeter RS, Barratt TM. Alternative treatment to corticosteroids in steroid sensitive idiopathic nephrotic syndrome. Arch Dis Child 1994; 71: 522-526
14. Trompeter RS, Lloyd BW, Hicks J, White RH, Cameron JS. Long-term outcome for children with minimal-change nephrotic syndrome. Lancet 1985; 1: 368-370
15. Sairam VK, Kalia A, Rajaraman S, Travis LB. Secondary resistance to cyclosporin A in children with nephrotic syndrome. Pediatr Nephrol 2002; 17: 842-846
16. Abeyagunawardena AS, Dillon MJ, Rees L, van't Hoff W, Trompeter RS. The use of steroid-sparing agents in steroid-sensitive nephrotic syndrome. Pediatr Nephrol 2003; 18: 919-924
17. Bock GH, Ongkingco JR, Patterson LT, Ruley J, Schroepfer LR, Nelson DL. Serum and urine soluble interleukin-2 receptor in idiopathic nephrotic syndrome. Pediatr Nephrol 1993; 7: 523-528
18. Consensus statement on management and audit potential for steroid responsive nephrotic syndrome. Report of a Workshop by the British Association for Paediatric Nephrology and Research Unit, Royal College of Physicians. Arch Dis Child 1994; 70: 151-157
19. Filler G. Treatment of nephrotic syndrome in children and controlled trials. Nephrol Dial Transplant 2003; 18 [Suppl 6]: V175-V178
20. Grimbert P, Audard V, Remy P, Lang P, Sahali D. Recent approaches to the pathogenesis of minimal-change nephrotic syndrome. Nephrol Dial Transplant 2003; 18: 245-248
21. Fakhouri F, Bocquet N, Taupin P et al. Steroid-sensitive nephrotic syndrome: from childhood to adulthood. Am J Kidney Dis 2003; 41: 550-557