Secondary resistance to cyclosporin A in children with nephrotic syndrome

Pediatric Nephrology

Volumn 17, Issue 10, 2002, Pages 842-846

  Sairam, Vellore K ^a   Kalia, Alok ^a   Rajaraman, Srinivasan ^a   Travis, Luther B ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Cyclosporin A; End stage renal disease; Focal segmental glomerulosclerosis; Steroid dependent nephrotic syndrome; Steroid resistant nephrotic syndrome

Indexed keywords

CYCLOSPORIN A; PREDNISONE; STEROID;

ARTICLE; CHILD; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG SENSITIVITY; DRUG WITHDRAWAL; FEMALE; FOCAL GLOMERULOSCLEROSIS; HUMAN; KIDNEY BIOPSY; KIDNEY FAILURE; MALE; NEPHROTIC SYNDROME; PRIORITY JOURNAL; RELAPSE; RISK ASSESSMENT;

ALKYLATING AGENTS; CHILD, PRESCHOOL; CYCLOSPORINE; DRUG RESISTANCE; FEMALE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; MALE; NEPHROTIC SYNDROME; RETROSPECTIVE STUDIES; STEROIDS;

EID: 0036951984     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-002-0896-0     Document Type: Article

References (31)

1. Neuhaus TJ, Burger HR, Klingler M, Fanconi A, Leumann EP (1992) Long-term low dose cyclosporin A in steroid dependent nephrotic syndrome of childhood. Eur J Pediatr 151:775-778
2. Ponticelli C, Edefonti A, Ghio L, Rizzoni G, Rinaldi S, Gusmano R, Lama G, Zacchello G, Confalonieri R, Altieri P, Bettinelli A, Maschio G, Cinotti GA, Fuiano G, Schena FP, Castellani A, Della Casa-Alberighi O (1993) Cyclosporin versus cyclophosphamide for patients with steroid dependent and frequently relapsing idiopathic nephrotic syndrome: a multicentre randomized controlled trial. Nephrol Dial Transplant 8:1326-1332
3. Tanaka R, Yoshikawa N, Kitano Y, Ito H, Nakamura H (1993) Long-term cyclosporin A treatment in children with steroid dependent nephrotic syndrome. Pediatr Nephrol 7:249-252
4. Hulton SA, Neuhaus TJ, Dillon MJ, Barratt TM (1994) Long-term cyclosporin treatment of minimal change nephrotic syndrome of childhood. Pediatr Nephrol 8:401-403
5. Takeda A, Ohgushi H, Niimura F, Matsutani H (1998) Long-term effects of immunosuppressants in steroid dependent nephrotic syndrome. Pediatr Nephrol 12:746-750
6. Inoue Y, Iijima K, Nakamura H, Yoshikawa N (1999) Two-year cyclosporin treatment in children with steroid dependent nephrotic syndrome. Pediatr Nephrol 13:33-38
7. Tejani AT, Butt K, Trachtman H, Suthanthiran M, Rosenthal CJ, Khawar MR (1988) Cyclosporin A induced remission of relapsing nerphrotic syndrome in children. Kidney Int 33:729-734
8. Ponticelli C, Rizzoni G, Edefonti A, Altieri P, Rivolta E, Rinaldi S, Ghio L, Lusvarghi E, Gusmano R, Locatetlli F, Pasquali S, Castellani A, Della Casa-Alberighi OD (1993) A randomized trial of cyclosporine in steroid resistant idiopathic nephrotic syndrome. Kidney Int 43:1377-1384
9. Niaudet P (1994) Treatment of childhood steroid resistant idiopathic nephrosis with a combination of cyclosporine and prednisone, J Pediatr 125:981-986
10. Hymes LC (1995) Steroid-resistant, cyclosporin-responsive. relapsing nephrotic syndrome. Pediatr Nephrol 9:137-139
11. Niaudet P, Fuchshuber A, Gagnodoux MF, Habib R, Broyer M (1997) Cyclosporin in the therapy of steroid resistant idiopathic nephrotic syndrome.Kidney Int Suppl 58:S85-S90
12. Ingulli E, Singh A, Baqi N, Ahmad H, Moazami S, Tejani A (1995) Aggresive long-term cyclosporin therapy for steroid resistant focal segmental glomerulosclerosis. J Am Soc Nephrol 5:1820-1825
13. Melocoton TL, Kamil ES, Cohen AH, Fine RN (1991) Long-term cyclosporin A treatment of steroid resistant and steroid dependent nephrotic syndrome. Am J Kidney Dis 18:583-588
14. Niaudet P, Habib R (1994) Cyclosporin in the treatment of idiopathic nephrosis syndrome. J Am Soc Nephrol 5:1049-1055
15. Gregory MJ, Smoyer WE, Sedman A, Kershaw DB, Valentini RP, Johnson K, Bunchman TE (1996) Long-term cyclosporin therapy for pediatric nephrotic syndrome; a clinical and histologic analysis. J Am S Nephrol 7:543-549
16. Garcia C, Michelon T, Barros V, Mota D, Uhlmann A, Randon R, Ramalho H, Abbud Filho M (1998) Cyclosporin in the treatment of steroid dependent and steroid resistant idiopathic nephrotic syndrome in children. Transplant Proc 30:4156-4157
17. Singh A, Tejani C, Tejani A (1999) One-center experience with cyclosporin in refractory nephrotic syndrome in children. Pediatr Nephrol 13:26-32
18. Niaude P, Habib R, Tete MJ, Hinglais N, Broyer M (1987) Cyclosporin in the treatment of idiopathic nephrotic syndrome in children. Pediatr Nephrol 1:566-573
19. Habib R, Niaudet P (1994) Comparison between pre and post-treatment renal biopsies in children receiving cyclosporin for idiopathic nephrosis. Clin Nephrol 42:141-146
20. Seikaly MG, Prashner H, Nolde-Hurlbert B, Browne R (2000) Long-term clinical and pathological effects of cyclosporin in children with nephrosis. Pediatr Nephrol 14:214-217
21. Hino S, Takemura T, Okada M, Murakami K, Yagi K, Fukushima K, Yoshioka K (1998) Follow-up study of children with nephrotic syndrome treated with a long-term moderate dose of cyclosporin. Am J Kidney Dis 31:932-939
22. Anonymous (1978) Nephrotic syndrome in children: prediction of histpathology from clinical and laboratory characteristics at time of diagnosis. A report of International Study of Kidney Diseases in Children. Kidney Int 13:159-165
23. Anonymous (1981) The primary nephrotic syndrome in children. Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. A report of he International Study of Kidney Diseases in Children. J Pediatr 98:561-564
24. Anonymous (1982) Early identification of frequent rlapsers among children with minimal change nephrotic syndrome. A report of the International Study of Kidney Diseases in children. J Pediatr 101:514-518
25. Capodicasa G, De Santo NG, Nuzzi F, Giordano C (1986) Cyclosporin A in nephrotic syndrome of childhood. A 14 month experience. Int J Pediatr Nephrol 7:69-72
26. Hoyer PF, Krull F, Brodehl J (1986) Cyclosporin in frequently relapsing minimal change nephrotic syndrome. Lancet 2:335
27. Lagrue C, Laurel J, Belghiti D, Robeva R (1986) Cyclosporin and idiopathic nephrotic syndrome. Lancet 2:692-693
28. Cavallo T, Johnson MP (1981) Immunopathologic study of minimal change glomerular disease with mesangial IgM deposits. Nephron 27:281-284
29. Allen WR, Travis LB, Cavallo T, Brouhard BH, Cunningham RJ III (1982) Immune deposits and mesangial hypercellularity in minimal change nephrotic syndrome: clinical relavance. J Pediatr 100:188-191
30. Pardo V, Riesgo I, Zilleruelo G, Strauss J (1984) The clinical significance of mesangial IgM deposits and mesangial hyper-cellularity in minimal change nephrotic syndrome. Am J Kidney Dis 3:264-269
31. Hamar P, Peti-Peterdi J, Szabo A, Becker G, Flach R, Rosivall L, Heemann U (2001) Interleukin-2 dependent mechanisms are involved in the development of glomerulosclerosis after partial renal ablation in rats. Exp Nephrol 9:133-141