Pig spleen transplantation induces transient hematopoietic cell chimerism in baboons [2]

Xenotransplantation

Volumn 11, Issue 3, 2004, Pages 298-300

  Dor, F J M F ^a   Tseng, Y L ^a   Kuwaki, K ^a   Ko, D S C ^a   Cooper, D K C ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; CYCLOSPORIN; GALACTOSYLTRANSFERASE; UNCLASSIFIED DRUG;

ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; BABOON; CHIMERA; CONTROLLED STUDY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; IMMUNOLOGICAL TOLERANCE; IRRADIATION; LETTER; LYMPHOID TISSUE; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN TRANSPLANTATION; SURGICAL TECHNIQUE; SWINE; WILD TYPE; XENOTRANSPLANTATION;

ANIMALS; FLOW CYTOMETRY; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELLS; PAPIO; SPLEEN; SWINE; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HETEROLOGOUS;

EID: 2442538309     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2004.00131.x     Document Type: Letter

References (10)

1. DOR FJMF, GOLLACKNER B, COOPER DKC. Can spleen transplantation induce tolerance? A review of the literature. Transplant Int. 2003; 16: 451.
2. GOLLACKNER B, DOR FJMF, KNOSALLA C, et al. Spleen transplantation in miniature swine: surgical technique and results in MHC-matched donor and recipient pairs. Transplantation 2003; 75: 1799.
3. BOHLER L, AWWAD M, DOWN JD, et al. Pig hematopoietic cell chimerism in baboons conditioned with a nonmyeloablative regimen and CD154 blockade. Transplantation 2002; 73: 12.
4. TSENG Y-L, DOR FJMF, KUWAKI K, et al. Initial results of bone marrow transplantation from α1,3-galactosyl-transferase gene-knockout pigs in baboons (submitted for publication).
5. KOZLOWSKI T, MONROY R, XU Y, et al. Anti-Galα1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction. Transplantation 1998; 66: 176.
6. BASKER M, ALWAYN IPJ, BUHLER L, et al. Clearance of mobilized porcine peripheral blood progenitor cells is delayed by depletion of the phagocytic reticuloendothelial system in baboons. Transplantation 2001; 72: 1278.
7. OKADA S, NAKAUCHI H, NAGAYOSHi K, et al. Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule. Blood 1991; 78: 1706.
8. DOR FJMF, GOLLACKNER B, KUWAKI K, et al. Histopathology of spleen allograft rejection in miniature swine (submitted for publication).
9. DOR FJMF, RAMIREZ ML, ALTMAN EL, et al. Hematopoietic stem cells in the spleen: studies in the pig, baboon and human (submitted for publication).
10. EGUCHI H, KNOSALLA C, LAN P, et al. T cells from pre-sensitized donors fail to cause graft-versus-host responses or to facilitate donor hematopoietic cell engraftment in a pig-to-mouse xenotransplantation model (submitted for publication).