Mechanical strains and bone metabolism;Contraintes mécaniques et métabolisme osseux

Medecine Nucleaire

Volumn 28, Issue 2, 2004, Pages 67-76

  Maïmoun, Laurent ^a,b  

^a GRISMO   (France)

^b Centre Propara   (France)

Author keywords

Bone metabolism; Immobilization; Microgravity; Paraplegic patients; Physical activity

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE;

AGE; AGED; AGING; ATHLETE; BIOMECHANICS; BONE DENSITY; BONE MASS; BONE METABOLISM; BONE MINERAL; CHILD; CYCLING; ELECTROSTIMULATION THERAPY; EXERCISE; HUMAN; IMMOBILIZATION; MECHANICAL STRESS; MICROGRAVITY; OSTEOLYSIS; OSTEOPOROSIS; PARAPLEGIA; PHYSICAL ACTIVITY; PHYSICAL EDUCATION; REVIEW; RISK FACTOR; SITTING; SPACE FLIGHT; SWIMMING;

EID: 2442503550     PISSN: 09281258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (111)

1. Wolff J.D. Das gesetz der transformationde knochen. Berlin 1892;Ahirschwald.
2. Frost H.M. A determinant of bone architecture. The minimum effective strain. Clin. Orthop 1983; 286-92.
3. Biering-Sfrensen F., Bohr H., Schaadt O. Bone mineral content of the lumbar spine and lower extremities years after spinal cord lesion. Paraplegia 1988; 26: 293-301.
4. Leblanc A., Schneider V., Evans HJ et al. Bone mineral density and recovery after 17 weeks of bed rest. J Bone Miner Res 1990; 8: 843-850.
5. Vico L., Collet P., Guignandon A. et al. Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts. Lancet 2000; 355: 1607-11.
6. Minaire P., Meunier P.J., Edouard C. et al. Quantitative histologic data on disuse osteoporosis, comparison with histological data. Calcif Tssue Int 1974; 17: 57-73.
7. Palle S., Vico L., Bourrin S., Alexandre C. Bone tissue response four-month anthiorthostatic bedrest: a bone histomorphometric study. Calcif Tissue Int 1992; 51: 189-194.
8. Nilsson B.E. & Westlin N.E. Bone density in athletes. Clin. Orthop 1971; 77: 179-182.
9. Duncan R.L. & Turner C.H. Mechanotransduction and the functional response of bone to mechanical strain. Calcif Tissue Int 1995; 57: 344-358.
10. Binderman I, Shimshoni Z, Somjen D. Biochemical pathways involved in the translation of physical stimulus into biological message. Calcif Tissue Intern 1984; 36: S82-S85.
11. Klein-Nulend J., Van der Plas A., Semiens C.M. et al. Sensitivity of osteocytes to biomechanical stress in vitro. FASEB J 1995; 9: 441-445.
12. Rubin C. T. and Lanyon L.E. Osteoregulatory nature of mecanical stimuli: Function as a determinant for adaptative remodelling in bone. J Orthop Res 1987; 5: 300-310.
13. Etherington J., Mac Gregor A.J., Spector T.D. Genes determine the BMD response to exercise. J Bone Miner Res 1997; 12:Abs S 559.
14. Fehling P.C., Alekel L., Clasey J. et al. A comparison of bone mineral densities among female athletes in impact loading and active loading sports. Bone 1995; 17: 205-210.
15. Conroy B.P., Kraemer W.J., Maresh C.M. et al. Bone mineral density in elite junior olympic weightlifters. Med Sci Sports Exerc. 1993; 25: 1103-1109.
16. Karlsson M.K., Johnell O., Obrant K.J. Bone mineral density in weight lifters. Calcif Tissue Int 1993; 52: 212-215.
17. Courteix D., Lespessailles E., Peres S.L. et al. Effect of physical training on bone mineral density in prepupertal girls: a comparative study between impact-loading and non-impact-loading sports. Osteoporosis Int 1998; 8: 152-158.
18. Maimoun L, Lumbroso S, Manetta J, et al. Testosterone is significantly reduced in endurance athletes without impact on bone mineral density. Horm Res 2003; 59: 285-92.
19. Morel J., Combe B., Francisco J., Bernard J. Bone mineral density of 704 amateur sportsmen involved in different physical activities. Osteoporosis Int 2001; 12: 152-157.
20. Taaffe D.R., Duret C., Cooper C.S., Marcus R. Comparaison of calcaneal ultrasound and DXA in young women. Med Sci Sports Exerc 1999; 31: 1484-1489.
21. Warner S.E., Shaw J.M., Dalsky G.P. Bone mineral density of competitive male mountain and road cyclists. Bone 2002; 30: 281-286.
22. Dalsky G.P. Exercise: its effect on bone mineral content. Clin Gynecol 1987; 30: 820-831.
23. Cassell C., Benedict M., Specker B. Bone mineral density in elite 7-to-9-year-old female gymnasts and swimmers. Med Sci Sports Exerc 1996; 28: 1243-1246.
24. Nickols-Richardson S., Modlesky C.M., O'Connor P.J., Lewis R.D. Premenarcheal gymnasts possess higher bone mineral density than controls. Med Sci Sports Exerc 2000; 32: 63-69.
25. Courteix D., Lespessailles E., Obert P., Benhamou C.L. Skull bone mass deficit in prepubertal highly-trained gymnast girls. Int J Sports Med 1999; 20: 328-333.
26. Rico, H., Revilla M., Hernandez E.R. et al. Bone mineral content and body composition in postpubertal cyclist boys. Bone 1993; 15: 93-95.
27. Kannus P., Haapasalo H., Sankelo M., et al. Effect of starting age of physical activity on bone mass in the dominant arm of tennis and squash players. Annal Intern Medical 1995; 123: 27-31.
28. Bradney M., Pearce G., Naughton G. et al. Moderate exercise during growth in prepubertal boys: changes in bone mass, size, volumetric density, and bone strength: a controlled prospective study. J Bone Miner Res 1998; 13: 1814-21.
29. Mackelvie K.J., McKay H.A., Khan K.M., Crocker P.R. A school-based exercise intervention augments bone mineral accrual in early pubertal girls. J Pediatr 2001; 139: 501-8.
30. Fuchs R.K., Bauer J.J., Snow C.M. Jumping improves hip and lumbar spine bone mass in prebubescent children: a randomized controlled trials. J Bone Miner Res 2001; 16: 148-156.
31. Consensus Development Conference. Diagnosis, prophylaxis and treatment of osteoporosis. Am J Med 1993; 94: 646-650.
32. Frost H.M. Why do bone strength and "mass" in aging adults become unresponsive to vigorous exercise? Insights of the Utah paradigm. J Bone Miner Metabol 1999; 17: 90-7.
33. Smith E.L., Gilligan C., McAdam M. et al. Deterring bone loss by exercise intervention in premenopausal and post-menopausal women. Calcif Tissue Int 1989; 44: 312-321.
34. Dalsky GP, Stocke KS, Eshani A.A et al. Weight bearing exercise training and lumbar bone mineral content. Ann Int Med 1988, 108: 824-828.
35. Winters K.M., Snow C.M. Detraining reverses positive effects of exercise on the musculoskeletal system in premenopausal women. J Bone Miner Res 2000; 15: 2495-2503.
36. Orwoll E., Ferar J., Oviatt S., et al. The relationship of swimming exercise to bone mass in men and women. Arch Inter Med 1989, 149: 2197-2200.
37. Cooper C., Barker D.J., Wickham C., Physical activity, muscle strengh, and calcium intake in fracture of the proximal femur in Britain. Br Med J 1988; 297: 1443-1446.
38. Lau E., Donnan S., Barker D.J., Cooper C. Physical activity and calcium intake in fracture of the proximal femur in Hong Kong. Br Med J 1988; 297: 1441-1443.
39. Paganini-Hill, Chao A., Ross R.K., Henderson B.E. Exercise and others factors in the prevention of hip fracture: the leisure World Study. Epidemiology 1991; 2: 16-25.
40. Lane N.E., Bloch D.A., Hubert H.B. et al. Running, osteoarthristis, and bone density: initial 2-year longitudinal study. Am J Med 1990; 88: 452-459.
41. Georgopoulos N., Markou K., Theodoropoulou A. et al. Growth and pubertal developement in elite female rhythmic gymnasts. J Clin Endocrinol Metab 1999; 84: 4525-4530.
42. Robinson T.L., Snow-harter C., Taaffe D.R. et al. Gymnast exhibit higher bone mass than runners despite similar prevalence of amenorrhea and oligomenorrhea. J Bone Miner Res 1995; 10: 26-35.
43. Kirchner E.M., Lewis R.D., O'Connor P.J. Bone mineral density and dietary intake of female college gymnasts. Med Sci Sports Exerc 1995; 27: 543-549.
44. Cann C.E., Martin M.C., Genant H.K., Jaffe R.B. Decreased spinal mineral content in amenorrheic women. JAMA 1984; 251: 626-629.
45. Myburgh K.H., Bachrach L.K., Lewis B. et al. Low bone mineral density at the axial and appendicular sites in amenorrheic athletes. Med Sci Sports Exerc 1993; 25: 1197-1202.
46. Gremion G., Rizzoli R., Slosman D. et al. Oligo-amenorrheic long-distance runners may lose more bone in spine than in femur. Med Sci Sports Exerc 2001; 33: 15-21.
47. Sabo D., Bernd L., Pfeil J., Reiter A. Bone quality in lumbar spine in high performance athletes. Eur Spine J 1996; 5: 258-263.
48. Stewart A.D. & Hannan J. Total and regional bone density in male runners, cyclists, and controls. Med Sci Sports Exerc 2000; 32: 1373-1377.
49. Bilamin J.E., Blanchard M.S., Russek-Cohen E. Lower vertebral bone density in male long distance runners. Med Sci Sports Exerc 1989; 21: 66-70.
50. Heatland M.L., Haardo J., Christiansen C. Low bone mass and high bone turnover in male long distance runners. J Clin Endocrinol Metab 1993; 77: 770-775.
51. Hackney A.C., Sinning W.E., Bruot B.C. Reproductive hormonal profiles of endurance-trained and untrained males. Med Sci Sports Exerc 1988; 20: 60-65.
52. Wheeler G.D., Singh M., Pierce W.D. et al. Endurance training decreases serum testosterone levels in men without change in luteinizing hormone pulsatile release. J Clin Endocrinol Metab 1991; 72: 422-425.
53. MacDougall J.D., Webber C., Martin J. et al. Relationship among running mileage, bone density, and serum testosterone in male runners. J Appl Physiol 1992; 73: 1165-1170.
54. Smith R. & Rutherford O.M. Spine and total body bone mineral density and serum testosterone levels in male athletes. Eur J App Physiol 1993; 67: 330-334.
55. Lucia A., Chicharro J.L., Perez M. et al. Reproductive function in male endurance athletes: sperm analysis and hormonal profile. J Appl Physiol 1996; 81: 2627-2636.
56. Hoogeveen A.R. & Zonderland M.L. Relationships between testosterone, cortisol and performance in professional cyclists. Int J Sports Med 1996; 17: 423-428.
57. Lutwak L., Whedon G.B., Lahance P.A. et al. Mineral electrolyte and nitrogen balance studies of the Gemini-VII fourteen day orbital space flight. J Clin Endocrinol Metab 1969; 29: 1140-1156.
58. Rambaut P.C., Leach C.S., Hebon G.D. A study of metabolic balance in crewmembers of skylab IV. Acta Astraunautica 1979; 6: 1313-1322.
59. LeBlanc A., Schneider V., Schackelford L. Bone Mineral and lean tissue loss after long duration spaceflight. J Bone Miner Res 1996; 11(Suppl): 323.
60. Leblanc A., Schackelford L., Schneider V. Future human bone research in space. Bone 1998; 22(suppl): 113-116.
61. Schneider V, Oganov V., LeBlanc A. et al. Spaceflight bone loss and change in fat and lean body mass. J Bone Miner Res 1992; 7(Suppl 1): S122.
62. Vico L., Chappard D., Palle S. et al. Trabecular bone remodeling after 7 days of weightlessness exposure (Biocosmos 1667). Am J Physiol 1988; 255: 242-7.
63. Morey E.R. & Baylink D.J. Inbibition of bone formation during spaceflight. Science 1978; 201: 1138-1141.
64. Shaw S.R., Vailas A.C., Grindelan R.E., Zernecke R.F. Effects of 1 week spaceflight on morphological and mechanical properties of growing bone. Am J Physiol 1988; 254: R78-R83.
65. Zerath E., Holy X., Malouvier A. et al. Rat an monkey bone study in the biocosmos 2044 space experiment. Physiologist 1991; 1: 194-195.
66. Caillot-Augusseau A., Lafarge-Proust M.H., Soler C. et al. Bone formation and resorption biological markers in cosmonauts during and after a 180-day space flight (Euromir 95). Clin Chem 1998; 44: 578-585.
67. Collet P, Uebelhart D., Vico L. et al. Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans. Bone 1997; 20: 547-51.
68. Smith S.C., Nillen J.L., Leblanc A. et al. Collagen Cross-link excretion during space flight and bed rest. J Clin Endocrinol Metab 1998; 83: 3584-3591.
69. Smith S.M., Wastney M.E., Morukov B.V. et al. Calcium metabolism before, during and after a 3-mo spaceflight: kinetic and biochemical changes. Am J Physiol 1999; 277: R1-R10.
70. Morey-Holton E.R., Schnoes H.K., Delucia H.F. et al. Vitamin D metabolites and bioactive parathyroid hormone levels during Spacelab 2. Aviat Space Environ Med 1988; 59: 1038-41.
71. Zerwekh J.E., Ruml L.A., Gottschalk F., Pack C.Y.C. The effects of twelve weeks of bed rest on bone histology, biochemical markers of bone turnover, and calcium homeostasis in eleven normal subjects. J Bone Miner Res 1998; 13: 594-1601.
72. Inoue H., Tanaka H., Moriwake T et al: Altered Biochemical markers of bone turnover in humans during 120 days of bed rest. Bone 2000; 26: 281-286.
73. Lueken S.A., Arnaud S.B., Taylor A.K., Baylink D. Changes in markers of bone formation and resorption in a bed rest model of weightlessness. J Bone Miner Res 1993; 8: 1433-1437.
74. Mundy G.R., Poser J.W: Chemotactic activity of the g-carboxyglutamic acid containing protein in bone. Calcif Tissue Int 1983; 35: 164-168.
75. Leblanc A., Schneider V., Spector E. et al. Calcium absorption, endogenous excretion, and endocrine changes during and after long-term bed rest. Bone 1995; 16: 301-304.
76. Maheshwart U.R., Schneider V.S., McDonald J. Fluoride balance studies in healthy men during bed rest with and without fluoride supplement. Am J Clin Nutr 1982; 36: 211-8.
77. Grigoriev A.I., Morukov B.V., Oganov V.S. et al. Effect of exercise and biphosphonate on mineral balance and bone density during 360 day antiorthostatic hypokinesia. J Bone Miner Res 1992; 7: 449-55.
78. Abramson A.S. Bone disturbances in injuries to the spinal cord and cauda equina paraplegia. Their prevention by ambulation. J Bone Jt Surg 1948, 30A: 982.
79. Covalt D.A., Cooper I.S., Hoen T.L., Rusk H.A. Early management of patients with spinal cord injury. JAMA 1953; 151: 89.
80. Bergmann P, Heilporn A, Schoutens A et al: Longitudinal study of calcium and bone metabolism in paraplegic patients. Paraplegia 1977-78; 15: 147-159.
81. Stewart AF, Adler MD, Byers CM et al: Calcium homeostasis in immobilization: an example of resorptive hypercalciuria. N Engl J Med 1982; 306: 1136-40.
82. Roberts D, Lee W, Cuneo RC, et al: Longitudinal study of bone turnover after acute spinal cord injury. J Clin Endocrinol Metab 1998; 83: 415-422.
83. Chantraine A., Nusgens B., Lapiere CM. Bone remodeling during the development of osteoporosis in paraplegia. Calcif Tissue Int 1986; 38: 323-327.
84. Leduc B.E., Lefebvre B., Puig P., Daigneault L. L'osteoporose souslesionnelle chez le blessé médullaire évaluée par ostéodensitométrie. Ann Readaptation Med Phys 1991; 34: 199-204.
85. Leslie W.D. & Nance P.W. Dissociated hip and spine demineralization: a specific finding in spinal cord injury. Arch Phys Med Rehabil 1993; 74: 960-964.
86. Jones L.M., Goulding A., Gerrard D.F. DEXA: a practical and accurate tool to demonstrate total and regional bone loss, lean tissue loss and fat mass gain in paraplegia. Spinal Cord 1998; 36: 637-640.
87. Demirel G., Yilmaz H., Paker N., Önel S. Osteoporosis after spinal cord injury. Spinal Cord 1998; 36: 822-825.
88. Tsuzuku S., Ikegami Y., Yabe K. Bone mineral density differences between paraplegic and quadriplegic patients: a cross-sectional study. Spinal Cord 1999 37: 358-361.
89. Biering-Sfrensen F., Bohr H., Schaadt O. Longitudinal study of bone mineral content in the lumbar spine, the forearm and the lower extremities after spinal cord injury. Eur J Clin Invest 1990; 20: 330-335.
90. Kannisto M., Alaranta H., Merikanto J. et al. Bone mineral status after pediatric spinal cord injury. Spinal Cord 1998; 36: 641-646.
91. Jaovisidha S, Sartoris DJ, Martin EME et al. Influence of heterotipic ossification of the hip on bone densitometry: a study in spinal cord injured patients. Spinal Cord 1998; 36: 647-653.
92. Finsen V., Indredavik B., Fougner K.J. Bone mineral and hormonal status in paraplegics. Paraplegia 1992;30: 343-347.
93. Garland D.E., Stewart C.A., Adkins R.H. et al. Osteoporosis after spinal cord injury. J Orthop Res 1992; 10: 371-378.
94. Dauty M., Perrouin Verbe B., Maugars Y. et al. Supralesional and sublesional bone mineral density in spinal cord-injured patients. Bone 2000; 27: 305-309.
95. Chantraine A. Clinical investigation of bone metabolism in spinal cord lesion. Paraplegia 1971; 8: 253-259.
96. Pietschmann P, Pils P., Woloszczuk W. et al. Increased serum osteocalcin levels in patients with paraplegia. Paraplegia 1992; 30: 204-209.
97. Uebelhart D., Hartmann D., Vuagnat H. et al. Early modifications of biochemical markers of bone metabolism in spinal cord injury patients. A preliminary study. Scand J Rehabil Med 1994; 26: 197-202.
98. Maïmoun L., Couret I., Micallef J.P. et al. Use of bone biochemical markers with DEXA to determine early bone loss in patients with spinal cord injury. Metabolism 2002; 51: 958-953.
99. Kiratli B.J., Agre J.C., Wilson M.A., Smith E.L. Comparaison of early vs late changes in bone mineral density in the first 18 months after spinal cord injury. Arch Phys Med Rehabil 1988; 69: 711.
100. Bauman W.A., Spungen A.M., Wang J. et al. Continuous loss of bone during chronic immobilization: a monozygotic twin study. Osteoporos Int 1999; 10: 123-127.
101. Vestergaard P., Krogh K., Rejnmark L., Mosekilde L. Fracture rates and risk factors for fractures in patients with spinal cord injury. Spinal Cord 1998; 36: 790-796.
102. Keating JF, Kerr M, Delargy M: Minimal trauma causing fractures in patients with spinal cord injury. Disabil Rehabil 1992; 14: 108-109.
103. Sipski M.L., Findley T.W., Glaser R.M. et al. Prevention of osteoporosis through early use of electrical stimulation after spinal cord injury. Arch Phys Med Rehabil 1990; 71: 795.
104. Mysiw W.J., Jackson R.D., Bloomfield S. Hypercalciuria prevented by fonctional electrical stimulation. Arch Phys Med Rehabil 1990, 71: 795.
105. Pacy P.J., Hesp R., Halliday D.A. et al. Muscle and bone paraplegic patients, and effect of functionnal electrical stimulation. Clin Sci 1988; 75: 481-487.
106. Minatre P., Depassio J., Berard E. et al. Effect of clodronate on immobilisation bone loss. Bone 1987; 8: S63-68.
107. Pearson E.G., Nance P.W., Leslie W.D., Ludwog S. Cyclical etidronate: its effect on bone density in patients with acute spinal cord injury. Arch Phys Med Rehabil 1997; 78: 269-272.
108. Chappard D., Minaire P., Privat C. et al. Effects of tiludronate on bone loss in paraplegic patients. J Bone Miner Res 1995; 10: 112-8.
109. Olgivie C., Bowker P., Rowley D.I. The physiological benefits of paraplegic orthotically aided walking. Paraplegia 1993, 31: 11-113.
110. Kunkel C.F., Scremin E., Eisenberg B. et al. Effect of "standing" on spasticity, contracture, and osteoporosis in paralysed males. Arch Phys Med Rehabil 1993; 74: 73-78.
111. Leeds E.M., Klose K.J., Ganz W. et al. Bone mineral density after bicycle ergometry training. Arch Phys Med Rehabil 1990; 71: 207-209.