Drosophila Male-Specific Lethal 2 Protein Controls Sex-Specific Expression of the roX Genes

Genetics

Volumn 166, Issue 4, 2004, Pages 1825-1832

  Rattner, Barbara P ^a,b   Meller, Victoria H ^a  

^a TUFTS UNIVERSITY   (United States)

^b SECTION OF MOLECULAR BIOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DROSOPHILA PROTEIN; MALE SPECIFIC LETHAL 2 PROTEIN; RNA; UNCLASSIFIED DRUG;

ARTICLE; DROSOPHILA; FEMALE; GENE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC CODE; GENETIC TRANSCRIPTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ROX GENE; SEX DETERMINATION; UPREGULATION; X CHROMOSOME;

ANIMALS; DNA-BINDING PROTEINS; DOSAGE COMPENSATION, GENETIC; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LARVA; MALE; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION FACTORS; TRANSFORMATION, GENETIC; X CHROMOSOME;

ARACHNIDA; HEXAPODA;

EID: 2442494140     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.166.4.1825     Document Type: Article

References (29)

1. AKHTAR, A., and P. B. BECKER, 2000 Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila. Mol. Cell 5: 367-375.
2. AKHTAR, A., D. ZINK and P. B. BECKER, 2000 Chromodomains are protein-RNA interaction modules. Nature 407: 405-409.
3. AMREIN, H., and R. AXEL, 1997 Genes expressed in neurons of adult male Drosophila. Cell 88: 459-469.
4. CHANG, K. A., and M. I. KURODA, 1998 Modulation of MSL1 abundance in female Drosophila contributes to the sex specificity of dosage compensation. Genetics 150: 699-709.
5. CLINE, T. W., and B. J. MEYER, 1996 Vive la difference: males vs females in flies vs worms. Annu. Rev. Genet. 30: 637-702.
6. COPPS, K., R. RICHMAN, L. M. LYMAN, & A. CHANG, J. RAMPERSAD-AMMONS et al., 1998 Complex formation by the Drosophila MSL proteins: role of the MSL2 RING finger in protein complex assembly. EMBO J. 17: 5409-5417.
7. GEBAUER, F., M. GRSKOVIC and M. W. HENTZE, 2003 Drosophila sex-lethal inhibits the stable association of the 40S ribosomal subunit with msl-2 mRNA. Mol. Cell 11: 1397-1404.
8. GU, W., P. SZAUTER and J. C. LUCCHESI, 1998 Targeting of MOF, a putative histone acetyl transferase, to the X chromosome of Drosophila melanogaster. Dev. Genet. 22: 56-64.
9. GU, W., X. WEI, A. PANNUTI and J. C. LUCCHESI, 2000 Targeting the chromatin-remodeling MSL complex of Drosophila to its sites of action on the X chromosome requires both acetyl transferase and ATPase activities. EMBO J. 19: 5202-5211.
10. HILFIKER, A., D. HILFIKER-KLEINER, A. PANNUTI and J. C. LUCCHESI, 1997 mof, a putative acetyl transferase gene related to the Tip60 and Moz human genes and to the Sas genes of yeast, is required for dosage compensation in Drosophila. EMBO J. 16: 2054-2060.
11. KAGEYAMA, Y., G. MENGUS, G. GILFILLAN, H. G. KENNEDY, C. STUCKENHOLZ et al., 2001 Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site. EMBO J. 20: 2236-2245.
12. KELLEY, R. L., I. SOLOVYEVA, L. M. LYMAN, R. RICHMAN, V. SOLOVYEV et al., 1995 Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila. Cell 81: 867-877.
13. KELLEY, R. L., J. WANG, L. BELL and M. I. KURODA, 1997 Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism. Nature 387: 195-199.
14. KELLEY, R. L., V. H. MELLER, P. R. GORDADZE, G. ROMAN, R. L. DAVIS et al., 1999 Epigenetic spreading of the Drosophila dosage compensation complex from roX RNA genes into flanking chromatin. Cell 98: 513-522.
15. LINDSLEY, D. L., and G. G. ZIMM, 1992 The Genome of Drosophila melanogaster. Academic Press, San Diego.
16. LYMAN, L. M., K. COPPS, L. RASTELLI, R. L. KELLEY and M. I. KURODA, 1997 Drosophila male-specific lethal-2 protein: structure/function analysis and dependence on MSL-1 for chromosome association. Genetics 147: 1743-1753.
17. MELLER, V. H., 2003 Initiation of dosage compensation in Drosophila embryos depends on expression of the roX RNAs. Mech. Dev. 120: 759-767.
18. MELLER, V. H., and M. I. KURODA, 2002 Sex and the single chromosome. Adv. Genet. 46: 1-24.
19. MILLER, V. H., and B. P. RATTNER, 2002 The roX genes encode redundant male-specific lethal transcripts required for targeting of the MSL complex. EMBO J. 21: 1084-1091.
20. MELLER, V. H., K. H. WU, G. ROMAN, M. I. KURODA and R. L. DAVIS, 1997 roX1 RNA paints the X chromosome of male Drosophila and is regulated by the dosage compensation system. Cell 88: 445-457.
21. MELLER, V. H., P. R. GORDADZE, Y. PARK, X. CHU, C. STUCKENHOLZ et al., 2000 Ordered assembly of roX RNAs into MSL complexes on the dosage-compensated X chromosome in Drosophila. Curr. Biol. 10: 136-143,
22. OH, H., Y. PARK and M. I. KURODA, 2003 Local spreading of MSL complexes from rox genes on the Drosophila X chromosome. Genes Dev. 17: 1334-1339.
23. PARK, Y., R. L. KELLEY, H. OH, M. I. KURODA and V. H. MELLER, 2002 Extent of chromatin spreading determined by roX RNA recruitment of MSL proteins. Science 298: 1620-1623.
24. PARK, Y., G. MENGUS, X. BAI, Y. KAGEYAMA, V. H. MELLER et al., 2003 Sequence-specific targeting of Drosophila roX genes by the MSL dosage compensation complex. Mol. Cell 11: 977-986.
25. RASTELLI, L., and M. I. KURODA, 1998 An analysis of maleless and histone H4 acetylation in Drosophila melanogaster spermatogenesis. Mech. Dev. 71: 107-117.
26. RASTELLI, L., R. RICHMAN and M. I. KURODA, 1995 The dosage compensation regulators MLE, MSL-1 and MSL-2 are interdependent since early embryogenesis in Drosophila. Mech. Dev. 53: 223-233.
27. RICHTER, L., J. R. BONE and M. I. KURODA, 1996 RNA-dependent association of the Drosophila maleless protein with the male X chromosome. Genes Cells 1: 325-336.
28. SMITH, E. R., A. PANNUTI, W. GU, A. STEURNAGEL, R. G. COOK et al., 2000 The Drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation. Mol. Cell. Biol. 20: 312-318.
29. ZHOU, S., Y. YANG, M. J. SCOTT, A. PANNUTI, K. C. FEHR et al., 1995 Male-specific lethal 2, a dosage compensation gene of Drosophila, undergoes sex-specific regulation and encodes a protein with a RING finger and a metallothionein-like cysteine cluster. EMBO J. 14: 2884-2895.