Soft tissue sarcomas treated with postoperative external beam radiotherapy with and without low-dose-rate brachytherapy

International Journal of Radiation Oncology Biology Physics

Volumn 59, Issue 2, 2004, Pages 475-480

  Andrews, Stephen F ^a   Anderson, Penny R ^a   Eisenberg, Burton L ^a   Hanlon, Alexandra L ^a   Pollack, Alan ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Brachytherapy; Local control; Radiotherapy; Sarcoma

Indexed keywords

DOSIMETRY; RADIOTHERAPY; TUMORS;

BRACHYTHERAPY; EXTERNAL BEAM RADIOTHERAPY (EBRT);

ONCOLOGY;

ADOLESCENT; ADULT; AGED; ARTICLE; BRACHYTHERAPY; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; HYPOTHESIS; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; METASTASIS; MULTIVARIATE ANALYSIS; POSTOPERATIVE CARE; PREDICTION; PRIORITY JOURNAL; RADIATION DOSE; SOFT TISSUE SARCOMA; STATISTICAL ANALYSIS; SURVIVAL RATE; SURVIVAL TIME; TREATMENT FAILURE; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRACHYTHERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MALE; MIDDLE AGED; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; SARCOMA; STATISTICS;

EID: 2442482771     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2003.10.048     Document Type: Article

References (17)

1. Cancer facts and figures. American Cancer Society; Atlanta, GA; 2002. p. 1-48
2. Rosenberg S., Tepper J., Glatstein E., et al. The treatment of soft-tissue sarcomas of the extremities, prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy. Ann Surg. 196:1982;305-315
3. Pollack A., Zagars G., Goswitz M.S., et al. Preoperative vs. postoperative radiotherapy in the treatment of soft tissue sarcomas A matter of presentation. Int J Radiat Oncol Biol Phys. 42:1998;563-572
4. Karasek K., Constine L.S., Rosier R. Sarcoma therapy Functional outcome and relationship to treatment parameters. Int J Radiat Oncol Biol Phys. 24:1992;651-656
5. O'Sullivan B., Davis A.M., Turcotte R., et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs A randomized trial. Lancet. 359:2002;2235-2241
6. Davis A.M., O'Sullivan B., Bell R.S., et al. Function and health status outcomes in a randomized trial comparing preoperative and postoperative radiotherapy in extremity soft tissue sarcoma. J Clin Oncol. 20:2002;4472-4477
7. Pisters P., Harrison L., Leung D., et al. Long-term results of prospective randomized trial of adjuvant brachytherapy in soft tissue sarcomas. J Clin Oncol. 14:1996;859-868
8. Alektiar K., Leung D., Zelefsky M., et al. Adjuvant brachytherapy for primary high-grade soft tissue sarcoma of the extremity. Ann Surg Oncol. 9:2002;48-56
9. Schray M., Gunderson M., Sim F., et al. Soft tissue sarcoma, integration of brachytherapy, resection and external irradiation. Cancer. 66:1990;451-456
10. Alekhteyar K., Leung D., Brennan M., et al. The effect of combined external beam radiotherapy and brachytherapy on local control and wound complications in patients with high-grade soft tissue sarcomas of the extremity with positive microscopic margins. Int J Radiat Oncol Biol Phys. 36:1996;321-324
11. Suit H., Mankin H., Wood W., et al. Treatment of the patient with stage M0 soft tissue sarcoma. J Clin Oncol. 6:1988;854-862
12. Barkley H.T. Jr, Martin R.G., Romsdahl M.M., et al. Treatment of soft tissue sarcomas by preoperative irradiation and conservative surgical resection. Int J Radiat Oncol Biol Phys. 14:1988;693-699
13. Alektiar K.M., Leung D., Zelefsky M.J., et al. Adjuvant radiation for stage II-B soft tissue sarcoma of the extremity. J Clin Oncol. 20:2002;1643-1650
14. Gherlinzoni F., Pignatti G., Fontana M., et al. Soft tissue sarcomas The experience at the Istituto Ortopedico Rizzoli. Chir Organi Mov. 75:1990;150-154
15. Ravaud A., Bui N.B., Coindre J.M., et al. Adjuvant chemotherapy with Cyvadic in high risk soft tissue sarcoma A randomized prospective trial. Adjuv Ther Cancer. 6:1990;556-566
16. Frustaci S., Gherlinzoni F., De Paoli A., et al. Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: Results of the Italian randomized cooperative trial. J Clin Oncol. 19:2001;1238-1247
17. Spiro IJ, Gebhrdt M, Springfield D, et al. Neoadjuvant chemotherapy and radiotherapy for large soft tissue sarcomas [Abstract]. Proc Am Soc Clin Oncol 1996;15:524