The effect of combined external beam radiotherapy and brachytherapy on local control and wound complications in patients with high-grade soft tissue sarcomas of the extremity with positive microscopic margin

International Journal of Radiation Oncology Biology Physics

Volumn 36, Issue 2, 1996, Pages 321-324

  Alekhteyar, Khaled M ^a,b   Leung, Dennis H ^a   Brennan, Murray F ^a   Harrison, Louis B ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b VA Medical Center   (United States)

Author keywords

Brachytherapy; External beam radiotherapy; Positive margin(s); Soft tissue sarcoma

Indexed keywords

ADULT; AGED; ARTICLE; BEAM THERAPY; BRACHYTHERAPY; CANCER CONTROL; CANCER SURGERY; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LIMB TUMOR; MAJOR CLINICAL STUDY; MALE; MICROSCOPY; PRIORITY JOURNAL; RADIATION DOSE; SOFT TISSUE SARCOMA; WOUND;

EID: 0030250402     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(96)00331-8     Document Type: Article

References (13)

1. 1. Arbeit, J.; Hilaris, B.; Brennan, M. Wound complications in the multimodality treatment of extremity and superficial trunccal sarcomas. J. Clin. Oncol. 5:480-488; 1987.
2. 2. Brennan, M.; Casper, E.; Harrison, L.; Shiu, M.; Garynor, S.; Hajdu, S. The role of multimodality therapy in soft tissue sarcoma. Ann. Surg. 214:328-338; 1991.
3. 3. Brennan, M. F.; Hilaris, B.; Shiu, M. H.; Lane, J.; Magill, G.; Friedrich, C.; Hajdu, S. I. Local recurrence in adult soft tissue sarcoma: A randomized trial of brachytherapy. Arch. Surg. 122:1289-1293; 1987.
4. 4. Consensus conference. Limb sparing treatment of adult soft tissue sarcomas and osleosarcomas. JAMA 254:1791-1794; 1985.
5. 5. Gemer, L.; Trowbridge, D.; Neff, J.; Lin, F.; Reddy, E.; Evans, R.; Hassanein, R. Local recurrence of soft tissue carcinoma following brachytherapy. Int. J. Radiat. Oncol. Biol. Phys. 20:587-592; 1991.
6. 6. Harrison, L. B.; Franzese, F.; Gaynor, J.; Brennan, M. F. Long-term results of a prospective randomized trial of adjuvant brachytherapy in the management of completely resected soft tissue sarcomas of the extremity and superficial trunk. Int. J. Radiat. Oncol. Biol. Phys. 27:259-265; 1993.
7. 7. Ormsby, M.; Hilaris, B.; Nori, D.; Brennan, M. Wound complications of adjuvant radiation therapy in patients with soft tissue sarcomas. Ann. Surg. 210:93-99; 1989.
8. 8. Pisters, P. W.; Harrison, L. B.; Woodruff, J. M.; Garynor, J. I.; Brennan, M. F. A prospective randomized trial of adjuvant brachytherapy in the management of low-grade soft tissue sarcomas of the extremity and superficial trunk. JCO 12:1150-1155; 1994.
9. 9. Rosenberg, S. A.; Tepper, J.; Glatstein, E.; Costa, J.; Young, R.; Baker, A.; Brennan, M.; DeMoss, E.; Seipp, C.; Sindelar, W.; Sugarbaker, P.; Wesley, R. The treatment of soft tissue sarcomas of the extremities. Prospective randomized evaluations of (1) Limb sparing surgery plus radiation compared with amputation; (2) The role of adjuvant chemotherapy. Ann. Surg. 196:305-315; 1982.
10. 10. Sadoski, C.; Suit, H.; Rosenberg, A.; Mankin, H.; Efird, J. Preoperative radiation, surgical margins, and local control of extremity sarcomas of soft tissues. J. Surg. Oncol. 52:223-230; 1993.
11. 11. Schray, M.; Gunderson, L.; Sim, F.; Pritchard, D.; Shives, T.; Yeakel, P. Soft tissue sarcoma - Integration of brachy-therapy, resection, and external irradiation. Cancer 66:451-456; 1990.
12. 12. Shiu, M.; Hilaris, B.; Harrison, L.; Brennan, M. Brachytherapy and function saving resection of soft tissue sarcoma arising in the limb. Int. J. Radiat. Oncol. Biol. Phys. 21:1485-1492; 1991.
13. 13. Tanabe, K.; Pollock, R.; Ellis, L.; Murphy, A.; Sherman, N.; Romsdahl, M. Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas. Cancer 73:1652-1659; 1994.