Pompilidotoxins: Novel peptide neurotoxins blocking sodium channel inactivation from solitary wasp venom

Current Medicinal Chemistry - Central Nervous System Agents

Volumn 4, Issue 2, 2004, Pages 139-146

  Konno, Katsuhiro ^a   Kawai, Nobufumi ^b  

^a INSTITUTO BUTANTAN   (Brazil)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Neurotoxin; Pompilidotoxin; Sodium channel inactivation; Solitary wasp venom

Indexed keywords

NEUROTOXIN; POMPILIDOTOXIN DERIVATIVE; SCORPION VENOM; SEA ANEMONE TOXIN; SODIUM CHANNEL; SODIUM ION; UNCLASSIFIED DRUG; VENOM;

AMINO ACID ANALYSIS; ANIMAL CELL; BINDING SITE; BRAIN CELL; BRAIN SLICE; CHIMERA; CLASSIFICATION; DISULFIDE BOND; DRUG ACTIVITY; GENE MUTATION; HEART; HIPPOCAMPUS; HUMAN; HUMAN CELL; INSECT; LARVAL DEVELOPMENT; NEUROMUSCULAR JUNCTION DISORDER; NONHUMAN; PEPTIDE ANALYSIS; PRESYNAPTIC NERVE; PREY; RAT; REVIEW; SODIUM TRANSPORT; SPIDER; STRUCTURE ACTIVITY RELATION; SYNAPSE; SYNAPTIC TRANSMISSION; TRIGEMINUS GANGLION; WASP;

EID: 2442452796     PISSN: 15680150     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568015043357020     Document Type: Review

References (35)

1. Harvey, A.L.; Anderson, A.J.; Rowan, E.G. In Natural and Synthetic Neurotoxins; Harvey, A.L., Ed.; Academic Press: London, 1993; pp. 129-185.
2. Piek, T.; Spanjer, W. In Venoms of the Hymenoptera: Biochemical, Pharmacological and Behavioural Aspects; Piek, T., Ed.; Academic Press: London, 1986; pp. 161-307.
3. Hisada, M.; Konno, K.; Itagaki, Y.; Naoki, H.; Nakajima, T. Rapid Commun. Mass Spectr., 2000, 14, 1828.
4. Hisada, M.; Konno, K.; Itagaki, Y.; Naoki, H.; Nakajima, T. Rapid Commun. Mass Spectr., 2002, 16, 1040.
5. Konno, K.; Hisada, M.; Naoki, H.; Itagaki, Y.; Yasuhara, T.; Juliano, M.A.; Juliano, L.; Palma, M.S.; Nakajima, T. Toxicon, 2001, 39, 1257.
6. Yasuhara, T.; Mantel, P.; Nakajima, T.; Piek, T. Toxicon, 1987, 25, 527.
7. Piek, T.; Hue, S.; Mantel, P.; Nakajima, T.; Pelhate, M.; Yasuhara, T. Comp. Biochem. Physiol., 1990, 96C, 157.
8. Piek, T.; Hue, B.; Mony, L.; Nakajima, T.; Pelhate, M.; Yasuhara, T. Comp. Biochem. Physiol., 1987, 87C, 287.
9. Eldefrawi, A.T.; Eldefrawi, M.E.; Konno, K.; Mansour, N.A.; Nakanishi, K., Oltz, E.; Usherwood, P.N.R. Proc. Natl. Acad. Sci. USA, 1988, 85, 4907.
10. Piek, T.; Fokkens, R.H.; Karst, H.; Kruk, C.; Lind, A.; van Marle, J.; Nakajima, T.; Nibbering, N.M.M.; Shinozaki, H.; Spanjer, W.; Tong, Y. C. In Neurotox '88: Molecular Basis of Drug and Pesticide Action; Lunt, G.G. Ed.; Elsevier: Amsterdam; 1988, pp. 61-76.
11. Nakanishi, K.; Goodnow, R.; Konno, K.; Niwa, M.; Bukownik, R.; Kalimopoulos, T.A.; Usherwood, P.N.R.; Eldefrawi, A.T.; Eldefrawi, M.E. Pure & Appl. Chem., 1990, 62, 1223.
12. Piek, T.; Hue, B. Comp. Biochem. Physiol., 1989, 93c, 403.
13. Konno, K.; Miwa, A.; Takayama, H.; Hisada, M.; Itagaki, Y.; Naoki, H.; Yasuhara, T.; Kawai, N. Neurosci. Lett., 1997, 238, 102.
14. Konno, K.; Hisada, M.; Miwa, A.; Itagaki, Y.; Naoki, H.; Kawai, N.; Yasuhara, T.; Takayama, H. Biochem. Biophys. Res. Commun., 1998, 250, 612.
15. Konno, K.; Palma, M.S.; Hirata, I.Y.; Juliano, M.A.; Juliano, L.; Yasuhara, T. Toxicon, 2001, 40, 309.
16. Konno, K.; Hisada, M.; Naoki, H.; Itagaki, Y.; Kawai, N.; Miwa, A.; Yasuhara, T.; Morimoto, Y.; Nakata, Y. Toxicon, 2000, 38, 1505.
17. Konno, K.; Hisada, M.; Fontana, R.; Lorenzi, C.C.B., Naoki, H.; Itagaki, Y.; Miwa, A.; Kawai, N.; Nakata, Y.; Yasuhara, T.; Ruggiero Neto, J.; de Azevedo Jr., W.F.; Palma, M.S.; Nakajima, T. Biochim. Biophys. Acta, 2001, 1550, 70.
18. Konno, K.; Hisada, M.; Naoki, H.; Itagaki, Y.; Yasuhara, T.; Nakata, Y.; Miwa, A.; Kawai, N. Neurosci. Lett., 2000, 285, 29.
19. Catterall, W.A. Ann. Rev. Pharmacol. Toxicol., 1980, 20, 15.
20. Strichartz, G.; Rando, T.; Wang, G.K. Ann. Rev. Neurosci., 1987, 10, 237.
21. Catterall, W.A. Annu. Rev. Biochem., 1995, 64, 493.
22. Gallagher, M.J.; Blumenthal, K.M. J. Biol. Chem., 1994, 269, 254.
23. Khera, P.K.; Benzinger, G.R.; Lipkind, G.; Drum, C.L.; Hanck, D.A.; Blumenthal, K.M. Biochemistry, 1995, 34, 8533.
24. Loret, E.P.; del Valle, R.M.; Mansuelle, P.; Sampieri, F.; Rochat, H. J. Biol. Chem., 1994, 269, 16785.
25. Rogers, J.C.; Qu, Y.; Tanada, T.N.; Scheuer, T.; Catterall, W.A. J. Biol. Chem., 1996, 271, 15950.
26. West, L.W.; Patton, D.E.; Scheuer, T.; Wang, Y.; Goldwin, A.L.; Catterall, W.A. Proc. Natl. Acad. Sci. USA, 1992, 89, 10910.
27. Zilberberg, N.; Froy, O.; Loret, E.; Cestele, S.; Arad, D.; Gordon, D.; Gurevitz, M. J. Biol. Chem., 1997, 272, 14810.
28. Kawai, N.; Niwa, A. J. Physiol. (Lond.), 1980, 305, 73-85.
29. Sahara, Y.; Gotoh, M.; Konno, K.; Miwa, A.; Tsubokawa, H.; Robinson H.P.C., Kawai, N. Eur. J. Neurosci., 2000, 12, 1961.
30. Roy, M. L.; Narahashi, T. J. Neurosci., 1992, 12, 2104.
31. Harsch, A.; Konno, K.; Takayama, H.; Kawai, N.; Robinson, H. Neurosci. Lett., 1998, 252, 49.
32. Robinson, H.P.C.; Kawahara, Y.; Jimbo, M.; Torimitsu, K.; Kuroda, Y.; Kawana, A. J. Neurophysiol., 1993, 70, 1606.
33. Yokota, H.; Tsubokawa, H.; Miyawaki, T.; Konno, K.; Nakayama, H.; Masuzawa, T.; Kawai, N. Neurosci. Res., 2001, 41, 365.
34. Miyawaki, T.; Tsubokawa, H.; Yokota, H.; Oguro, K.; Konno, K.; Masuzawa, T.; Kawai, N. Neurosci. Lett., 2002, 328, 25.
35. Kinoshita, E.; Maejima, E.; Yamaoka, K.; Konno, K.; Kawai, N.; Shimizu, E.; Nakayama, H.; Seyama, I. Mol. Pharmacol., 2001, 59, 1457.