Novel G-protein coupled receptor ligands and neurohypophysial hormones

Journal of Neuroendocrinology

Volumn 16, Issue 4, 2004, Pages 378-382

  Ueta, Yoichi ^a   Ozaki, Y ^a   Saito, J ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

G protein coupled receptors; Galanin like peptide; Neuromedin U; PVN; SON

Indexed keywords

CORTICOTROPIN; G PROTEIN COUPLED RECEPTOR; GALANIN LIKE PEPTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; LIPOPOLYSACCHARIDE; MESSENGER RNA; NEUROHYPOPHYSIS HORMONE; NEUROMEDIN U; OXYTOCIN; PROTEIN C FOS; SODIUM CHLORIDE; VASOPRESSIN;

ANIMAL CELL; ASTROCYTE; BLOOD LEVEL; CONTROLLED STUDY; DEHYDRATION; HORMONAL REGULATION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; NEUROHYPOPHYSIS; NONHUMAN; OXYTOCIN RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVIEW; SALT LOADING; SUPRAOPTIC NUCLEUS; THALAMUS MIDLINE NUCLEUS; VASOPRESSIN RELEASE;

ANIMALS; LIGANDS; PITUITARY GLAND; PITUITARY HORMONES; RECEPTORS, G-PROTEIN-COUPLED;

EID: 2442445151     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0953-8194.2004.01179.x     Document Type: Review

References (50)

1. Civelli O, Nothacker HP, Saito Y, Wang Z, Lin SH, Reinscheid RK. Novel neurotransmitters as natural ligands of orphan G-protein-coupled receptors. Trends Neurosci 2001; 24: 230-237.
2. Meunier JC, Mollereau C, Toll L, Suaudeau C, Moisand C, Alvinerie P, Butour JL, Guillemot JC, Ferrara P, Monsarrat B, Mazarguil H, Vassart G, Parmentier M, Costentin J. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 1995; 377: 532-535.
3. Reinscheid RK, Nothacker HP, Bourson A, Ardati A, Henningsen RA, Bunzow JR, Grandy DK, Langen H, Monsma FJ Jr, Civelli O. Orphanin FQ. a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 1995; 270: 792-794.
4. Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M. Orexins and orexin receptors. a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998; 92: 573-585.
5. Hinuma S, Habata Y, Fujii R, Kawamata Y, Hosoya M, Fukusumi S, Kitada C, Masuo Y, Asano T, Matsumoto H, Sekiguchi M, Kurokawa T, Nishimura O, Onda H, Fujino M. A prolactin-releasing peptide in the brain. Nature 1998; 393: 272-276.
6. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999; 402: 656-660.
7. Minamino N, Kangawa K, Matsuo H. Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord. Biochem Biophys Res Commun 1985; 130: 1078-1085.
8. Domin J, Ghatei MA, Chohan P, Bloom SR. Characterization of neuromedin U like immunoreactivity in rat, porcine, guinea-pig and human tissue extracts using a specific radioimmunoassay. Biochem Biophys Res Commun 1986; 140: 1127-1134.
9. O'Harte F, Bockman CS, Zeng W, Abel PW, Harvey S, Conlon JM. Primary structure and pharmacological activity of a nonapeptide related to neuromedin U isolated from chicken intestine. Peptides 1991; 12: 809-812.
10. Howard AD, Wang R, Pong SS, Mellin TN, Strack A, Guan XM, Zeng Z, Williams DL Jr, Feighnr SD, Nunes CN, Murphy B, Stair JNYuH, Jiang Q, Clements MK, Tan CP, McKee KK, Hreniuk DL, McDonald TP, Lynch KR, Evans JF, Austin CP, Caskey CT, Van der Ploeg LH, Liu Q. Identification of receptors for neuromedin U and its role in feeding. Nature 2000; 406: 70-74.
11. Fujii R, Hosoya M, Fukusumi S, Kawamata Y, Habata Y, Hinuma S, Onda H, Nishimura O, Fujino M. Identification of neuromedin U as the cognate ligand of the orphan G protein-coupled receptor FM-3. J Biol Chem 2000; 275: 21068-21074.
12. Szekeres PG, Muir AI, Spinage LD, Miller JE, Butler SI, Smith A, Rennie GI, Murdock PR, Fitzgerald LR, Wu HI, McMillan LJ, Guerrera S, Vawter L, Elshourbagy NA, Mooney JL, Bergsma DJ, Wilson S, Chamhers JK. Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. J Biol Chem 2000; 275: 20247-20250.
13. Kojima M, Haruno R, Nakazato M, Date Y, Murakami N, Hanada R, Matsuo H, Kangawa K. Purification and identification of neruromedin U as an endogenous ligand for an orphan receptor GPR66 (FM3). Biochem Biophys Res Commun 2000; 276: 435-438.
14. Honzawa M, Sudoh T, Minamino, N, Tohyama M, Matsuo H. Topographic localization of neuromedin U-like structures in the rat brain: an immunohistochemical study. Neuroscience 1987; 23: 1103-1122.
15. Ballesta J, Carlei F, Bishop AE, Steel JH, Gibson SJ, Fahey M, Hennessey R, Domin J, Bloom SR, Polak JM. Occurrence and developmental pattern of neuromedin U-immunoreactive nerves in the gastrointestinal tract and brain of the rat. Neuroscience 1988; 25: 797-816.
16. Brown DR, Quito FL. Neuromedin U octapeptide alters ion transport in porcine jejunum. Eur J Pharmacol 1988; 155: 159-162.
17. Malendowicz LK, Nussdorfer GG, Markowska A, Tortorella C, Nowak M, Warchol JB. Effects of neuromedin U (NMU)-8 on the rat hypothalamo-pituitary-adrenal axis. Evidence of a direct effect of NMU-8 on the adrenal gland. Neuropeptides 1994; 26: 47-53.
18. Nakazato M, Hanada R, Murakami N, Date Y, Mondal NIS, Kojima M, Yoshimatsu H, Kangawa K, Matsukura S. Central effects of neuromedin U in the regulation of energy homeostasis. Biochem Biophys Res Commun 2000; 277: 191-194.
19. Wren AM, Small CJ, Abbott CR, Jethwa PH, Kennedy AR, Murphy KG, Stanley SA, Zollner AN, Ghatei MA, Bloom SR. Hypothalamic actions of neuromedin U. Endocrinology 2002; 143: 4227-4234.
20. YuXH, Cao CQ, Mennicken F, Puma C, Dray A, O'Donnell D, Ahmad S, Perkins M. Pro-nociceptive effects of neuromedin U in rat. Neuroscience 2003; 120: 467-474.
21. Ozaki Y, Onaka T, Nakazato M, Saito J, Kanemoto K, Matsumoto T, Ueta Y. Centrally administered neuromedin U activates neurosecretion and induction of c-fos messenger ribonucleic acid in the paraventricular and supraoptic nuclei of rat. Endocrinology 2002; 143: 4320-4329.
22. Ivanov TR, Lawrence CB, Stanley PJ, Luckman SM. Evaluation of neuromedin U actions in energy homeostasis and potuitary function. Endocrinology 2002; 143: 3813-3821.
23. Rokkaku K, Onaka T, Okada N, Ideno J, Kawakami A, Honda K, Yada T, Ishibashi S. Neuromedin U facilitates oxytocin release from the pituitary via beta adrenoceptors. Neuroreport 2003; 14: 1997-2000.
24. Qui DL, Chu CP, Shirasaka T, Nabekura T, Kunitake T, Kato K, Nakazato M, Katoh T, Kannan H. Neuromedin U depolarizes rat hypothalamic paraventricular nucleus neurons in vitro by enhancing IH channel activity. J Neurophysiol 2003; 90: 843-850.
25. Tatemoto K, Rokaeus A, Jornvall H, McDonald TJ, Mutt V. Galanin: a novel biologically active peptide from porcine intestine. FEBS Lett 1983; 164: 124-128.
26. Bartfai T, Hokfelt T, Langel U. Galanin - a neuroendocrine peptide. Crit Rev Neurobiol 1993; 7: 229-274.
27. Crawley JN. The role of galanin in feeding behavior. Neuropeptides 1999; 33: 369-375.
28. Merchenthaler I, Lopez FJ, Negro-Vilar A. Anatomy and physiology of central galanin-containing pathways. Prog Neurobiol 1993; 40: 711-769.
29. Habert-Ortoli E, Amiranoff B, Loquet I, Laburthe M, Mayaux JF. Molecular cloning of a functional human galanin receptor. Proc Natl Acad Sci USA 1994; 91: 9780-9783.
30. Howard AD, Tan C, Shiao LL, Palyha OC, McKee KK, Weinberg DH, Feighner SD, Cascieri MA, Smith RG, Van Der Ploeg LH, Sullivan KA. Molecular cloning and characterization of a new receptor for galanin. FEBS Lett 1997; 405: 285-290.
31. Wang S, He C, Hashemi T, Bayne M. Cloning and expressional characterization of a novel galanin receptor. Identification of different pharmacophores within galanin for the three galanin receptor subtypes. J Biol Chem 1997; 272: 31949-31952.
32. Branchek TA, Smith KE, Gerald C, Walker MW. Galanin receptor subtypes. Trends Pharmacol Sci 2000; 21: 109-117.
33. Tempel DL, Leibowitz KJ, Leibowitz SF. Effects of PVN galanin on macronutrient selection. Peptides 1988; 9: 309-314.
34. Hooi SC, Maiter DM, Martin JB, Koenig JI. Galaninergic mechanisms are involved in the regulation of corticotropin and thyrotropin secretion in the rat. Endocrinology 1990; 127: 2281-2289.
35. Burazin TVD, Larm JA, Ryan MC, Gundlach AL. Galanin-R1 and R2 receptor mRNA expression during the development of rat brain suggests differential subtype involvement in synaptic transmission and plasticity. Eur J Neurosci 2000; 12: 2901-2917.
36. Meister B, Cortés R, Villar MJ, Schalling M, Hökfelt T. Peptides and transmitter enzymes in hypothalamic magnocellular neurons after administrarion of hyperosmotic stimuli. Comparison between messenger RNA and peptide/protein levels. Cell Tissue Res 1990; 260: 279-297.
37. Landry M, Åman K, Hölfelt T. Galanin-R1 receptor in anterior and mid-hypothalamus. Distribution and regulation. J Comp Neurol 1998; 399: 321-340.
38. Landry M, Roche D, Calas A. Short-term effects of centrally administered galanin on the hyperosmotic stimulated expression of vasopressin in the rat hypothalamus. An in situ and immunohistochemistry study. Neuroendocrinology 1995; 61: 393-404.
39. Sweerts BW, Jarrett B, Lawrence AJ. Expression of preprogalanin mRNA following acute and chronic restraint stress in brains of normotensive and hypertensive rats. Mol Brain Res 1999; 69: 113-123.
40. Ohtaki T, Kumano S, Ishibashi Y, Ogi K, Matsui H, Harada M, Kitada C, Kurokawa T, Onda H, Fujino M. Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus. J Biol Chem 1999; 274: 37041-37045.
41. Juréus A, Cunningham MJ, McClain ME, Clifton DK, Steiner RA. Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat. Endocrinology 2000; 141: 2703-2706.
42. Kerr NC, Holmes FE, Wynick D. Galanin-like peptide (GALP) is expressed in rat hypothalamus and pituitary, but not in DRG. Neuroreport 2000; 11: 3903-3913.
43. Larm JA, Gundlach AL. Galanin-like peptide (GALP) mRNA expression is restricted to arcuate nucleus of hypothalamus in adult male rat brain. Neuroendocrinology 2000; 72: 67-71.
44. Lawrence CB, Baudoin FMH, Luckman SM. Centrally administered galanin-like peptide modifies food intake in the rat: a comparison with galanin. J Neuroendocrinol 2002; 13: 853-860.
45. Matsumoto H, Noguchi J, Takatsu Y, Horikoshi Y, Kumano S, Ohtaki T, Kitada C, Itoh T, Onda H, Nishimura O, Fujino M. Stimulation effect of galanin-like peptide (GALP) on lutenizing hormone-releasing hormone-mediated lutenizing hormone (LH) secretion in male rats. Endocrinology 2001; 142: 3693-3696.
46. Shen J, Larm JA, Gundlach AL. Galanin-like peptide mRNA in neural lobe of rat pituitary. Increased expression after osmotic stimulation suggests a role for galanin-like peptide in neuron-glial interactions and/or neurosecretion. Neuroendocrinology 2001; 73: 2-11.
47. Fujiwara K, Adachi S, Usui K, Maruyama M, Matsumoto H, Ohtaki T, Kitada C, Onda H, Fujino M, Inoue K. Immunocytochemical localization of a galanin-like peptide (GALP) in pituicytes of the rat posterior pituitary gland. Neurosci Lett 2002; 317: 65-68.
48. Saito J, Ozaki Y, Ohnishi H, Nakamura T, Ueta Y. Induction of galanin-like peptide gene expression in the rat posterior pituitary gland during endotoxin shock and adjuvant arthritis. Mol Brain Res 2003; 113: 124-132.
49. Kasting NW, Mazurek MF, Martin JB. Endotoxin increases vasopressin release independently of known physiological stimuli. Am J Physiol 1985; 248: E420-E424.
50. Chowdrey HS, Larsen PJ, Harbuz MS, Jessop DS, Aguilera G, Eckland DJ, Lightman SL. Evidence for arginine vasopressin as the primary activator of the HPA axis during adjuvant-induced arthritis. Br J Pharmacol 1995; 116: 2417-2424.