Design and synthesis of chromogenic thiopeptolide substrates as MetAPs active site probes

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 11, 2004, Pages 2853-2861

  Cui, Yong Mei ^a   Li, Jing Ya ^a   Chen, Ling Ling ^a   Li, Jia ^a   Ye, Qi Zhuang ^a,b   Nan, Fa Jun ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

Chromogenic thiopeptolide substrates; Methionine aminopeptidases

Indexed keywords

CHROMOGENIC SUBSTRATE; METHIONYL AMINOPEPTIDASE;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVITY; ENZYME SYNTHESIS; ESCHERICHIA COLI; HYDROLYSIS; MUTANT; PROTON NUCLEAR MAGNETIC RESONANCE; WILD TYPE;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; ANIMALS; BINDING SITES; CHROMOGENIC COMPOUNDS; CYCLOSPORINS; ESCHERICHIA COLI; HUMANS; HYDROLYSIS; METHIONINE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; POINT MUTATION; SULFHYDRYL COMPOUNDS;

ESCHERICHIA COLI;

EID: 2442426106     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.03.044     Document Type: Article

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