메뉴 건너뛰기




Volumn 46, Issue 9, 2005, Pages 1923-1932

Molecular and mechanistic characterization of platelet-activating factor-like bioactivity produced upon LDL oxidation

Author keywords

Atherogenesis; Low density lipoprotein; Mediators of inflammation; Oxidized phospholipids; Platelet activating factor acetylhydrolase; Platelet activating factor transacetylase

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; 1 O ALKYLGLYCERO 3 PHOSPHORYLCHOLINE; LOW DENSITY LIPOPROTEIN; THROMBOCYTE ACTIVATING FACTOR;

EID: 24344435114     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M500074-JLR200     Document Type: Article
Times cited : (21)

References (46)
  • 1
    • 0033552883 scopus 로고    scopus 로고
    • Mechanism of disease: Atherosclerosis-an inflammatory disease
    • Ross, R. 1999. Mechanism of disease: atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340: 115-126.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 115-126
    • Ross, R.1
  • 2
    • 0024603895 scopus 로고
    • Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
    • Steinberg, D., S. Parthasarathy, T. E. Carew, J. C. Khoo, and J. L. Witztum. 1989. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320: 915-924.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 915-924
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 4
    • 0030799043 scopus 로고    scopus 로고
    • Low density lipoprotein oxidation and its pathobiological significance
    • Steinberg, D. 1997. Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 272: 20963-20966.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20963-20966
    • Steinberg, D.1
  • 7
    • 17144424304 scopus 로고    scopus 로고
    • Phospholipid mediators in the vessel wall: Involvement in atherosclerosis
    • Ninio, E. 2005. Phospholipid mediators in the vessel wall: involvement in atherosclerosis. Curr. Opin. Clin. Nutr. Metab. Care. 8: 123-131.
    • (2005) Curr. Opin. Clin. Nutr. Metab. Care , vol.8 , pp. 123-131
    • Ninio, E.1
  • 9
    • 0029582870 scopus 로고
    • Platelet-activating factor receptor: Gene expression and signal transduction
    • Izumi, T., and T. Shimizu. 1995. Platelet-activating factor receptor: gene expression and signal transduction. Biochim. Biophys. Acta. 1259: 317-333.
    • (1995) Biochim. Biophys. Acta , vol.1259 , pp. 317-333
    • Izumi, T.1    Shimizu, T.2
  • 10
    • 0029164660 scopus 로고
    • Lipid ester-bound aldehydes among cooper-catalyzed peroxidation products of human plasma lipoproteins
    • Kamido, H., A. Kuksis, L. Marai, and J. J. Myher. 1995. Lipid ester-bound aldehydes among cooper-catalyzed peroxidation products of human plasma lipoproteins. J. Lipid Res. 36: 1876-1886.
    • (1995) J. Lipid Res. , vol.36 , pp. 1876-1886
    • Kamido, H.1    Kuksis, A.2    Marai, L.3    Myher, J.J.4
  • 11
    • 0030448750 scopus 로고    scopus 로고
    • Lipid peroxidation in low density lipoproteins from human plasma and egg yolk promotes accumulation of 1-acyl analogues of platelet activating factor like lipids
    • Tokumura, A., M. Toujima, Y. Yoshioka, and K. Fukuzawa. 1996. Lipid peroxidation in low density lipoproteins from human plasma and egg yolk promotes accumulation of 1-acyl analogues of platelet activating factor like lipids. Lipids. 31: 11251-11258.
    • (1996) Lipids , vol.31 , pp. 11251-11258
    • Tokumura, A.1    Toujima, M.2    Yoshioka, Y.3    Fukuzawa, K.4
  • 12
    • 0028849870 scopus 로고
    • Oxidatively modified LDL contains phospholipids with platelet activating factor like activity and stimulates the growth of smooth muscle cells
    • Heery, J. M., M. Kozak, D. M. Stafforini, D. A. Jones, G. A. Zimmerman, T. M. McIntyre, and S. M. Prescott. 1995. Oxidatively modified LDL contains phospholipids with platelet activating factor like activity and stimulates the growth of smooth muscle cells. J. Clin. Invest. 96: 2322-2330.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2322-2330
    • Heery, J.M.1    Kozak, M.2    Stafforini, D.M.3    Jones, D.A.4    Zimmerman, G.A.5    McIntyre, T.M.6    Prescott, S.M.7
  • 13
    • 0025783171 scopus 로고
    • Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor
    • Smiley, P. L., K. E. Stremler, S. M. Prescott, G. A. Zimmerman, and T. M. McIntyre. 1991. Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor. J. Biol. Chem. 266: 11104-11110.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11104-11110
    • Smiley, P.L.1    Stremler, K.E.2    Prescott, S.M.3    Zimmerman, G.A.4    McIntyre, T.M.5
  • 14
    • 0033588208 scopus 로고    scopus 로고
    • Evidence that phospholipid oxidation products and/or platelet-activating factor play an important role in early atherogenesis: In vitro and in vivo inhibition by WEB 2086
    • Subbanagunder, G., N. Leitinger, P. T. Shih, K. F. Faull, and J. A. Berliner. 1999. Evidence that phospholipid oxidation products and/or platelet-activating factor play an important role in early atherogenesis: in vitro and in vivo inhibition by WEB 2086. Circ. Res. 85: 311-318.
    • (1999) Circ. Res. , vol.85 , pp. 311-318
    • Subbanagunder, G.1    Leitinger, N.2    Shih, P.T.3    Faull, K.F.4    Berliner, J.A.5
  • 15
    • 0034739463 scopus 로고    scopus 로고
    • The expanding superfamily of phospholipase A2 enzymes: Classification and characterization
    • Six, D. A., and E. A. Dennis. 2000. The expanding superfamily of phospholipase A2 enzymes: classification and characterization. Biochim. Biophys. Acta. 1488: 1-19.
    • (2000) Biochim. Biophys. Acta , vol.1488 , pp. 1-19
    • Six, D.A.1    Dennis, E.A.2
  • 16
    • 0019789918 scopus 로고
    • A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3- phosphocholine (a hypotensive and platelet-activating lipid)
    • Blank, M. L., T. C. Lee, V. Fitzgerald, and F. Snyder. 1981. A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid). J. Biol. Chem. 256: 175-178.
    • (1981) J. Biol. Chem. , vol.256 , pp. 175-178
    • Blank, M.L.1    Lee, T.C.2    Fitzgerald, V.3    Snyder, F.4
  • 17
    • 0023278621 scopus 로고
    • Human plasma platelet-activating factor acetylhydrolase: Association with lipoprotein particles and role in the degradation of platelet-activating factor
    • Stafforini, D. M., T. M. McIntyre, M. E. Carter, and S. M. Prescott. 1987. Human plasma platelet-activating factor acetylhydrolase: association with lipoprotein particles and role in the degradation of platelet-activating factor. J. Biol. Chem. 262: 4215-4222.
    • (1987) J. Biol. Chem. , vol.262 , pp. 4215-4222
    • Stafforini, D.M.1    McIntyre, T.M.2    Carter, M.E.3    Prescott, S.M.4
  • 18
    • 0024536159 scopus 로고
    • An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma
    • Stremler, K. E., D. M. Stafforini, S. M. Prescott, G. A. Zimmerman, and T. M. McIntyre. 1989. An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma. J. Biol. Chem. 264: 5331-5334.
    • (1989) J. Biol. Chem. , vol.264 , pp. 5331-5334
    • Stremler, K.E.1    Stafforini, D.M.2    Prescott, S.M.3    Zimmerman, G.A.4    McIntyre, T.M.5
  • 19
    • 0028284804 scopus 로고
    • Hydrolysis and transesterification of platelet-activating factor by lecithin-cholesterol acyltransferase
    • Liu, M., and P. V. Subbaiah. 1994. Hydrolysis and transesterification of platelet-activating factor by lecithin-cholesterol acyltransferase. Proc. Natl. Acad. Sci. USA. 91: 6035-6039.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 6035-6039
    • Liu, M.1    Subbaiah, P.V.2
  • 20
    • 0035878795 scopus 로고    scopus 로고
    • Platelet-activating acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein
    • Tsoukatos, D. C., T. A. Liapikos, A. D. Tselepis, M. J. Chapman, and E. Ninio. 2001. Platelet-activating acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein. Biochem. J. 357: 457-464.
    • (2001) Biochem. J. , vol.357 , pp. 457-464
    • Tsoukatos, D.C.1    Liapikos, T.A.2    Tselepis, A.D.3    Chapman, M.J.4    Ninio, E.5
  • 21
    • 0028352168 scopus 로고
    • Platelet-activating factor formation during oxidative modification of low-density lipoprotein when PAF-acetylhydrolase has been inactivated
    • Liapikos, T. A., S. Antonopoulou, S-A. P. Karabina, D. C. Tsoukatos, C. A. Demopoulos, and A. D. Tselepis. 1994. Platelet-activating factor formation during oxidative modification of low-density lipoprotein when PAF-acetylhydrolase has been inactivated. Biochim. Biophys. Acta. 1212: 353-360.
    • (1994) Biochim. Biophys. Acta , vol.1212 , pp. 353-360
    • Liapikos, T.A.1    Antonopoulou, S.2    Karabina, S.-A.P.3    Tsoukatos, D.C.4    Demopoulos, C.A.5    Tselepis, A.D.6
  • 22
    • 0028269118 scopus 로고
    • PAF-acether-degrading acetylhydrolase in plasma LDL is inactivated by cooper- and cell-mediated oxidation
    • Dentan, C., P. Lesnik, M. J. Chapman, and E. Ninio. 1994. PAF-acether-degrading acetylhydrolase in plasma LDL is inactivated by cooper- and cell-mediated oxidation. Arterioscler. Thromb. 14: 353-360.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 353-360
    • Dentan, C.1    Lesnik, P.2    Chapman, M.J.3    Ninio, E.4
  • 23
    • 0028236549 scopus 로고
    • Distribution of PAF-acetylhydrolase activity in human plasma low-density lipoprotein subfractions
    • Karabina, S. A, P., T. A. Liapikos, G. Grekas, J. Goudevenos, and A. D. Tselepis. 1994. Distribution of PAF-acetylhydrolase activity in human plasma low-density lipoprotein subfractions. Biochim. Biophys. Acta. 1213: 34-38.
    • (1994) Biochim. Biophys. Acta , vol.1213 , pp. 34-38
    • Karabina, S.A.P.1    Liapikos, T.A.2    Grekas, G.3    Goudevenos, J.4    Tselepis, A.D.5
  • 24
    • 0029113036 scopus 로고
    • PAF-degrading acetylhydrolase is preferentially associated with dense LDL and VHDL-1 in human plasma. Catalytic characteristics and relation to the monocyte-derived enzyme
    • Tselepis, A. D., C. Dentan, S. A. P. Karabina, M. J. Chapman, and E. Ninio. 1995. PAF-degrading acetylhydrolase is preferentially associated with dense LDL and VHDL-1 in human plasma. Catalytic characteristics and relation to the monocyte-derived enzyme. Arterioscler. Thromb. Vasc. Biol. 15: 1764-1773.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1764-1773
    • Tselepis, A.D.1    Dentan, C.2    Karabina, S.A.P.3    Chapman, M.J.4    Ninio, E.5
  • 27
    • 0024086871 scopus 로고
    • Semisynthetic preparation of 1-O-hexadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine (platelet-activating factor)
    • Lekka, M. E., D. C. Tsoukatos, A. D. Tselepis, and V. M. Kapoulas. 1988. Semisynthetic preparation of 1-O-hexadecyl-2-acetyl-sn-glyceryl-3- phosphorylcholine (platelet-activating factor). Z. Naturforsch. 43c: 665-670.
    • (1988) Z. Naturforsch. , vol.43 C , pp. 665-670
    • Lekka, M.E.1    Tsoukatos, D.C.2    Tselepis, A.D.3    Kapoulas, V.M.4
  • 28
    • 70449246528 scopus 로고
    • Phosphorus assay in column chromatography
    • Barlett, G. R. 1959. Phosphorus assay in column chromatography. J. Biol. Chem. 234: 466-468.
    • (1959) J. Biol. Chem. , vol.234 , pp. 466-468
    • Barlett, G.R.1
  • 29
    • 0001887906 scopus 로고
    • Chromatographic separation, identification and analysis of phosphatidates
    • Marinetti, G. V. 1962. Chromatographic separation, identification and analysis of phosphatidates. J. Lipid Res. 3: 1-28.
    • (1962) J. Lipid Res. , vol.3 , pp. 1-28
    • Marinetti, G.V.1
  • 30
    • 0017069601 scopus 로고
    • Lipid transport in the avian species. Part I. Isolation and characterization of apolipoproteins and major lipoprotein density classes of male turkey serum
    • Kelley, J. L., and P. Alaupovic. 1976. Lipid transport in the avian species. Part I. Isolation and characterization of apolipoproteins and major lipoprotein density classes of male turkey serum. Atherosclerosis. 24: 155-175.
    • (1976) Atherosclerosis , vol.24 , pp. 155-175
    • Kelley, J.L.1    Alaupovic, P.2
  • 32
    • 0030041824 scopus 로고    scopus 로고
    • Pefabloc, 4-[2-aminoethyl]benzenesulfonyl fluoride, is a new, potent nontoxic and irreversible inhibitor of PAF-degrading acetylhydrolase
    • Dentan, C., A. D. Tselepis, M. J. Chapman, and E. Ninio. 1996. Pefabloc, 4-[2-aminoethyl]benzenesulfonyl fluoride, is a new, potent nontoxic and irreversible inhibitor of PAF-degrading acetylhydrolase. Biochim. Biophys. Acta. 1299: 353-357.
    • (1996) Biochim. Biophys. Acta , vol.1299 , pp. 353-357
    • Dentan, C.1    Tselepis, A.D.2    Chapman, M.J.3    Ninio, E.4
  • 33
    • 0020616462 scopus 로고
    • Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipids
    • Morel, D. W., J. R. Hessler, and G. M. Chilsom. 1983. Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipids. J Lipid Res. 24: 1070-1076.
    • (1983) J Lipid Res. , vol.24 , pp. 1070-1076
    • Morel, D.W.1    Hessler, J.R.2    Chilsom, G.M.3
  • 34
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 36
    • 0017769869 scopus 로고
    • Structural analysis of purified platelet-activating factor by upases
    • Benveniste, J., J-P. Le Couedic, J. Polonsky, and M. Tence. 1977. Structural analysis of purified platelet-activating factor by upases. Nature. 269: 170-171.
    • (1977) Nature , vol.269 , pp. 170-171
    • Benveniste, J.1    Le Couedic, J.-P.2    Polonsky, J.3    Tence, M.4
  • 38
    • 0025875571 scopus 로고
    • Biosynthesis of platelet activating factor and 1-0-acyl analogues by endothelial cells
    • Clay, K. L., C. Johnson, and S. Worthen. 1991. Biosynthesis of platelet activating factor and 1-0-acyl analogues by endothelial cells. Biochim. Biophys. Acta. 1094: 43-50.
    • (1991) Biochim. Biophys. Acta , vol.1094 , pp. 43-50
    • Clay, K.L.1    Johnson, C.2    Worthen, S.3
  • 39
    • 0027723521 scopus 로고
    • Biology of disease. PAF molecular heterogeneity: Pathobiological implications
    • Mac Manus, L. M., D. S. Woodward, S. I. Deavers, and R. N. Pinckard. 1993. Biology of disease. PAF molecular heterogeneity: pathobiological implications. Lab. Invest. 69: 639-650.
    • (1993) Lab. Invest. , vol.69 , pp. 639-650
    • Mac Manus, L.M.1    Woodward, D.S.2    Deavers, S.I.3    Pinckard, R.N.4
  • 42
    • 0028107094 scopus 로고
    • Reinvestigation of lipid peroxidation of linolenic acid
    • Mlakar, A., and G. Spiteller. 1994. Reinvestigation of lipid peroxidation of linolenic acid. Biochim. Biophys. Acta. 1214: 209-212.
    • (1994) Biochim. Biophys. Acta , vol.1214 , pp. 209-212
    • Mlakar, A.1    Spiteller, G.2
  • 43
    • 0023371167 scopus 로고
    • Secondary products of lipid oxidation
    • Frankel, E. N. 1987. Secondary products of lipid oxidation. Chem. Phys. Lipids. 44: 73-85.
    • (1987) Chem. Phys. Lipids , vol.44 , pp. 73-85
    • Frankel, E.N.1
  • 44
    • 0033934565 scopus 로고    scopus 로고
    • Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase
    • Tokumura, A., T. Sumida, M. Toujima, K. Kogure, K. Fukuzawa, Y. Takahashi, and S. Yamamoto. 2000. Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase. J. Lipid Res. 41: 953-962.
    • (2000) J. Lipid Res. , vol.41 , pp. 953-962
    • Tokumura, A.1    Sumida, T.2    Toujima, M.3    Kogure, K.4    Fukuzawa, K.5    Takahashi, Y.6    Yamamoto, S.7
  • 45
    • 33845557937 scopus 로고
    • Bicyclic endoperoxides and synthetic applications
    • Balci, M. 1981. Bicyclic endoperoxides and synthetic applications. Chem. Rev. 81: 91-108.
    • (1981) Chem. Rev. , vol.81 , pp. 91-108
    • Balci, M.1
  • 46
    • 0023238808 scopus 로고
    • Atherosclerosis and biochemical composition of coronary arteries in Finish men
    • Yla-Herttuala, S., H. Sumuvuori, K. Karkola, M. Mottonen, and T. Nikk. 1987. Atherosclerosis and biochemical composition of coronary arteries in Finish men. Atherosclerosis. 65: 109-115.
    • (1987) Atherosclerosis , vol.65 , pp. 109-115
    • Yla-Herttuala, S.1    Sumuvuori, H.2    Karkola, K.3    Mottonen, M.4    Nikk, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.