A comparison of raloxifene and calcium plus Vitamin D on vaginal atrophy after discontinuation of long-standing postmenopausal hormone therapy in osteoporotic women: A randomized, masked-evaluator, one-year, prospective study

Maturitas

Volumn 52, Issue 1, 2005, Pages 70-77

  Checa, M A ^a   Garrido, A ^a   Prat, M ^a   Conangla, M ^a   Rueda, C ^a   Carreras, R ^a  

^a HOSPITAL DEL MAR   (Spain)

Author keywords

Calcium; Postmenopausal symptoms; Quality of life; Raloxifene; Transdermal estrogen replacement therapy; Vaginal maturation index

Indexed keywords

CALCIUM; CALCIUM PLUS VITAMIN D; ESTRADIOL; ESTRADIOL VALERATE; OSTINE; PROGESTERONE; RALOXIFENE; UNCLASSIFIED DRUG; VITAMIN D;

ADULT; ALLERGIC REACTION; ARTICLE; BREAST CANCER; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG WITHDRAWAL; DYSPAREUNIA; ERYTHEMA; ESTRADIOL BLOOD LEVEL; ESTROGEN THERAPY; FEMALE; HEADACHE; HEART PALPITATION; HORMONAL THERAPY; HOT FLUSH; HUMAN; ISCHEMIA; LEG BLOOD FLOW; MASTALGIA; MATURATION; NAUSEA; NORMAL HUMAN; OSTEOPOROSIS; PATIENT; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SHORT FORM 36; STOMACH DISEASE; URINE INCONTINENCE; VAGINA ATROPHY; VAGINA EPITHELIUM; VARICOSIS;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; CALCIUM, DIETARY; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; HUMANS; LONGITUDINAL STUDIES; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; PROGESTERONE; PROSPECTIVE STUDIES; QUESTIONNAIRES; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VAGINAL DISEASES; VITAMIN D;

EID: 24144481837     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2004.12.006     Document Type: Article

References (23)

1. S. Hulley, D. Grady, and T. Bush Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/Progestin Replacement Study (HERS) Research Group J Am Med Assoc 280 1998 605 613
2. D. Grady, D. Herrington, and V. Bittner HERS research group. Cardiovascular disease outcomes during 6. 8 years of hormone therapy: Heart and Estrogen/Progestin Replacement Study Follow-up (HERS II) J Am Med Assoc 288 2002 49 57
3. J.E. Rossouw, G.L. Anderson, and R.L. Prentice Writing group for the women's health initiative investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial J Am Med Assoc 288 2002 321 323
4. M. Neves-e-Castro, G. Samsioe, M. Doren, and S.O. Skouby European menopause & andropause society. Results from WHI and HERS II-implications for women and the prescriber of HRT Maturitas 42 2002 255 258
5. B. Ettinger, D. Grady, A.N. Tosteson, A. Pressman, and J.L. Macer Effect of the Women's Health Initiative on women's decisions to discontinue postmenopausal hormone therapy Obstet Gynecol 102 2003 1225 1232
6. A.L. Hersh, M.L. Stefanick, and R.S. Stafford National use of postmenopausal hormone therapy: annual trends and response to recent evidence J Am Med Assoc 291 2004 47 53
7. L. Cardozo, G. Bachmann, D. McClish, D. Fonda, and L. Birgerson Meta-analysis of estrogen therapy in the management of urogenital atrophy in postmenopausal women: second report of the Hormones and Urogenital Therapy Committee Obstet Gynecol 92 1998 722 727
8. M.C. van der Linden, G. Gerretsen, M.S. Brandhorst, E.C. Ooms, C.M. Kremer, and W.H. Doesburg The effect of estriol on the cytology of urethra and vagina in postmenopausal women with genito-urinary symptoms Eur J Obstet Gynecol Reprod Biol 51 1993 29 33
9. S. Palacios, J. Calaf, A. Cano, J.J. Parrilla Spanish Menopause Society (AEEM) Relevant results of the WHI study for the management of the menopause in Spain Maturitas 44 2003 83 86
10. G.L. Wied Hormonal cytology C.M. Keebler TM. Somrak The manual of cytotechnology 1993 American Society of Clinical Pathologists Press Chicago, IL 62 72
11. A. Meisels The maturation value Acta Cytol 11 1967 249
12. J.E. Ware Jr., and C.D. Sherbourne The MOS 36-item short-form health survey (SF-36). I. Conceptual frame work and itemselection Med Care 30 1992 473 483
13. J. Alonso, L. Prieto, and J.M. Anto The Spanish version of the SF-36 Health Survey (the SF-36 health questionnaire): an instrument for measuring clinical results Med Clin (Barc) 104 1995 771 776
14. J. Alonso, E. Regidor, G. Barrio, L. Prieto, C. Rodriguez, and L. de la Fuente Population referente values of the Spanish version of the health questionnaire SF-36 Med Clin (Barc) 111 1998 410 416 [Article in Spanish]
15. M.C. Rees The need to improve compliance to HRT Br J Obstet Gynaecol 104 Suppl. 16 1997 1 3
16. Y. Shmuely, J.A. Berlin, J. Knauss, and E. Lydick Compliance with oral HRT in postmenopausal women in clinical trials-meta analysis Maturitas 41 2003 33 44
17. S.J. Neele, R. Evertz, A.R. Genazzani, M. Luisi, and C. Netelenbos Raloxifene treatment increases plasma levels of beta-endorphin in postmenopausal women: a randomized, placebo-controlled study Fertil Steril 77 2002 1110 1117
18. M.D. Vardy, R. Lindsay, and R.J. Scotti Short-term urogenital effects of raloxifene, tamoxifen, and estrogen Am J Obstet Gynecol 189 2003 81 88
19. S.R. Goldstein, P. Neven, L. Zhou, Y.L. Taylor, A.V. Ciaccia, and L. Plouffe Raloxifene effect on frequency of surgery for pelvic floor relaxation Obstet Gynecol 98 2001 91 96
20. S. Campbell, and M. Whitehead Oestrogen therapy and the menopausal syndrome Clin Obstet Gynaecol 4 1977 31 47
21. G.C. Davies, W.J. Huster, Y. Lu, L. Plouffe Jr., and M. Lakshmanan Adverse events reported by postmenopausal women in controlled trials with raloxifene Obstet Gynecol 93 1999 558 565
22. S. Gordon, B.W. Walsh, A.V. Ciaccia, S. Siddhanti, A.S. Rosen, and L. Plouffe Jr. Transition from estrogen-progestin to raloxifene in postmenopausal women: effect on vasomotor symptoms Obstet Gynecol 103 2004 267 273
23. L.E. Waetjen, J.S. Brown, K. Modelska, T. Blackwell, E. Vittinghoff, S.R. Cummings MORE Study Group Effect of raloxifene on urinary incontinence: a randomised controlled trial Obstet Gynecol 103 2004 261 266