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Volumn 14, Issue 6, 2005, Pages 511-520

Fabrication and characterization of a porous composite scaffold based on gelatin and hydroxyapatite for bone tissue engineering

Author keywords

Bone tissue engineering; Composite; Gelatin; Hydroxyapatite; Porosity

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADATION; BONE; CELLS; COMPOSITE MATERIALS; HYDROXYAPATITE; MORPHOLOGY; ORGANIC SOLVENTS; PORE SIZE; POROSITY; SCAFFOLDS;

EID: 24144475188     PISSN: 10261265     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (21)

References (56)
  • 1
    • 33645624957 scopus 로고    scopus 로고
    • Atlas of histology with functional correlations
    • Eroschenko V.P., Atlas of histology with functional correlations, Int. Ed., 45-61 (1996).
    • (1996) Int. Ed. , pp. 45-61
    • Eroschenko, V.P.1
  • 2
    • 0032212853 scopus 로고    scopus 로고
    • Hydroxyapatite fiber reinforced poly (α-hydroxy ester) foams for bone regeneration
    • Thomson R.C., Yaszemski M.J., Powers J.M., Mikos A.C., Hydroxyapatite fiber reinforced poly (α-hydroxy ester) foams for bone regeneration, Biomaterials, 19, 1935-1943 (1998).
    • (1998) Biomaterials , vol.19 , pp. 1935-1943
    • Thomson, R.C.1    Yaszemski, M.J.2    Powers, J.M.3    Mikos, A.C.4
  • 4
    • 0034672872 scopus 로고    scopus 로고
    • Scaffolds in tissue engineering bone and cartilage
    • Hutmacher D.W., Scaffolds in tissue engineering bone and cartilage, Biomaterials, 21, 2529-2543 (2000).
    • (2000) Biomaterials , vol.21 , pp. 2529-2543
    • Hutmacher, D.W.1
  • 5
    • 0034580476 scopus 로고    scopus 로고
    • Biomaterial developments for bone tissue engineering
    • Burg K.J.L., Porter S.T., Kellam J.F., Biomaterial developments for bone tissue engineering, Biomaterials, 21, 2347-2359 (2000).
    • (2000) Biomaterials , vol.21 , pp. 2347-2359
    • Burg, K.J.L.1    Porter, S.T.2    Kellam, J.F.3
  • 7
    • 0025961327 scopus 로고
    • Ultra-high-strength absorbable self-reinforced polyglycolide (SR-PGA) composite rods for internal fixation of bone fractures, in vitro and in vivo study
    • Törmälä P., Vasenius J., Vainionpää S., Laiho J., Pohjonen T., Rokkanen P., Ultra-high-strength absorbable self-reinforced polyglycolide (SR-PGA) composite rods for internal fixation of bone fractures, In vitro and in vivo study, J. Biomed. Mat. Res., 25, 1-22 (1991).
    • (1991) J. Biomed. Mat. Res. , vol.25 , pp. 1-22
    • Törmälä, P.1    Vasenius, J.2    Vainionpää, S.3    Laiho, J.4    Pohjonen, T.5    Rokkanen, P.6
  • 8
    • 0023119620 scopus 로고
    • The effects of fibre reinforcement and gold plating on the flexural and tensile strength of PGA/PLA copolymer materials in vitro
    • Törmälä P., Vainionpää S., Kilpikari J., Rokkanen P., The effects of fibre reinforcement and gold plating on the flexural and tensile strength of PGA/PLA copolymer materials in vitro, Biomaterials, 8, 42-45 (1987).
    • (1987) Biomaterials , vol.8 , pp. 42-45
    • Törmälä, P.1    Vainionpää, S.2    Kilpikari, J.3    Rokkanen, P.4
  • 12
    • 0034666760 scopus 로고    scopus 로고
    • Calcium-deficient hydroxyapatite-PLGA composites, Mechanical and microstructural investigation
    • Durucan C., Brown P.W., Calcium-deficient hydroxyapatite-PLGA composites, Mechanical and microstructural investigation, J. Biomed. Mater. Res., 51, 726-734 (2000).
    • (2000) J. Biomed. Mater. Res. , vol.51 , pp. 726-734
    • Durucan, C.1    Brown, P.W.2
  • 13
    • 0023484641 scopus 로고
    • Natural history of autografts and allografts
    • Goldberg V.M., Stevenson S., Natural history of autografts and allografts, Clin. Orthop., 225, 7-16 (1987).
    • (1987) Clin. Orthop. , vol.225 , pp. 7-16
    • Goldberg, V.M.1    Stevenson, S.2
  • 14
  • 15
    • 0015398492 scopus 로고
    • The current status of bone and joint transplants
    • Gregory C.F., The current status of bone and joint transplants, Clin. Orthop., 87, 165-66 (1972).
    • (1972) Clin. Orthop. , vol.87 , pp. 165-166
    • Gregory, C.F.1
  • 16
    • 0028070916 scopus 로고
    • Bone graft options, fact and fancy
    • Goldberg V.M., Stevenson S., Bone graft options, fact and fancy, Orthopedics, 17, 809-810, 821 (1994).
    • (1994) Orthopedics , vol.17 , pp. 809-810
    • Goldberg, V.M.1    Stevenson, S.2
  • 17
    • 0035255365 scopus 로고    scopus 로고
    • Engineering new bone tissue in vitro on highly porous poly(α-hydroxyl acids)/hydroxyapatite composite scaffolds
    • Ma P.X., Zhang R., Xiao G., Franceschi R., Engineering new bone tissue in vitro on highly porous poly(α-hydroxyl acids)/hydroxyapatite composite scaffolds, J. Biomed. Mater. Res., 54, 284-293 (2001).
    • (2001) J. Biomed. Mater. Res. , vol.54 , pp. 284-293
    • Ma, P.X.1    Zhang, R.2    Xiao, G.3    Franceschi, R.4
  • 18
    • 0034609615 scopus 로고    scopus 로고
    • Engineering three-dimensional bone tissue in vitro using biodegradable scaffolds, Investigating initial cell-seeding density and culture period
    • Holly C.E., Shoichet M.S., Davies J.E., Engineering three-dimensional bone tissue in vitro using biodegradable scaffolds, Investigating initial cell-seeding density and culture period, J. Biomed. Mater. Res., 51, 376-382 (2000).
    • (2000) J. Biomed. Mater. Res. , vol.51 , pp. 376-382
    • Holly, C.E.1    Shoichet, M.S.2    Davies, J.E.3
  • 19
    • 0034672876 scopus 로고    scopus 로고
    • Bone regeneration in segmental defects with resorbable polymeric membranes, does the polymer chemical composition affects the healing process
    • Gogolewski S., Pineda L., Busing C.M., Bone regeneration in segmental defects with resorbable polymeric membranes, does the polymer chemical composition affects the healing process, Biomaterials, 21, 2513-2520 (2000).
    • (2000) Biomaterials , vol.21 , pp. 2513-2520
    • Gogolewski, S.1    Pineda, L.2    Busing, C.M.3
  • 21
    • 0033622838 scopus 로고    scopus 로고
    • Growth of continuous bonelike mineral within porous poly(lactide-co- glycolide) scaffolds in vitro
    • Murphy W.L., Kohn D.H., Mooney D.J., Growth of continuous bonelike mineral within porous poly(lactide-co-glycolide) scaffolds in vitro, J. Biomed. Mater. Res., 50,50-58 (2000).
    • (2000) J. Biomed. Mater. Res. , vol.50 , pp. 50-58
    • Murphy, W.L.1    Kohn, D.H.2    Mooney, D.J.3
  • 22
    • 0027575137 scopus 로고
    • Laminated three-dimensional biodegradable foams for use in tissue engineering
    • Mikos A.G., Sarakinos G., Leite S.M., Vacanti J.P., Langer R., Laminated three-dimensional biodegradable foams for use in tissue engineering, Biomaterials, 14, 323-330 (1993).
    • (1993) Biomaterials , vol.14 , pp. 323-330
    • Mikos, A.G.1    Sarakinos, G.2    Leite, S.M.3    Vacanti, J.P.4    Langer, R.5
  • 23
    • 0023140396 scopus 로고
    • Strength and strength retention in vitro, of absorbable, self-reinforced polyglycolide (PGA) rods for fracture fixation
    • Vainionpää S., Kilpikari J., Laiho J., Helevirta P., Rokkanen P., Törmälä P., Strength and strength retention in vitro, of absorbable, self-reinforced polyglycolide (PGA) rods for fracture fixation, Biomaterials, 8, 46-48 (1987).
    • (1987) Biomaterials , vol.8 , pp. 46-48
    • Vainionpää, S.1    Kilpikari, J.2    Laiho, J.3    Helevirta, P.4    Rokkanen, P.5    Törmälä, P.6
  • 24
    • 0031195291 scopus 로고    scopus 로고
    • Ectopic bone formation by marrow stromal osteoblast transplantation using poly (DL-lactic-co-glycolic acid) foams implanted into the rat mesentery
    • Ishaug-Riley S.L., Crane G.M., Gurlek A., Miller M.J., Yasko A.W., Yaszemski M.J., Mikos A.G., Ectopic bone formation by marrow stromal osteoblast transplantation using poly (DL-lactic-co-glycolic acid) foams implanted into the rat mesentery, J. Biomed. Mater. Res., 36, 1-8 (1997).
    • (1997) J. Biomed. Mater. Res. , vol.36 , pp. 1-8
    • Ishaug-Riley, S.L.1    Crane, G.M.2    Gurlek, A.3    Miller, M.J.4    Yasko, A.W.5    Yaszemski, M.J.6    Mikos, A.G.7
  • 25
    • 0039132790 scopus 로고    scopus 로고
    • Three-dimensional nano HA/collagen matrix loading with osteogenic cells in organ culture
    • Du C., Cui F.Z., Zhu X.D., de Groot K., Three-dimensional nano HA/collagen matrix loading with osteogenic cells in organ culture, J. Biomed. Mater. Res., 44, 407-415 (1999).
    • (1999) J. Biomed. Mater. Res. , vol.44 , pp. 407-415
    • Du, C.1    Cui, F.Z.2    Zhu, X.D.3    De Groot, K.4
  • 26
    • 0032534714 scopus 로고    scopus 로고
    • Tissue response to nano-hydroxyapatite / collagen composite implants in marrow cavity
    • Du C., Cui F.Z., Feng Q.L., Zhu X.D., de Groot K., Tissue response to nano-hydroxyapatite / collagen composite implants in marrow cavity, J. Biomed. Mater. Res., 42, 540-548 (1998).
    • (1998) J. Biomed. Mater. Res. , vol.42 , pp. 540-548
    • Du, C.1    Cui, F.Z.2    Feng, Q.L.3    Zhu, X.D.4    De Groot, K.5
  • 27
    • 0012046774 scopus 로고
    • Experimental mineralization of collagen sponge and decalcified bone
    • Van de Putte K.A., Urist M.R., Experimental mineralization of collagen sponge and decalcified bone, Clin. Orthop. Rel. Res., 40, 48-56 (1965).
    • (1965) Clin. Orthop. Rel. Res. , vol.40 , pp. 48-56
    • Van De Putte, K.A.1    Urist, M.R.2
  • 28
    • 0020075032 scopus 로고
    • Repair of experimental bone defect with a collagen block containing synthesized apatite
    • Hayashi K., Yabuki T., Tabuchi K., Fujii T., Repair of experimental bone defect with a collagen block containing synthesized apatite, Arch. Orth. Trauma. Surg., 99,265 (1982).
    • (1982) Arch. Orth. Trauma. Surg. , vol.99 , pp. 265
    • Hayashi, K.1    Yabuki, T.2    Tabuchi, K.3    Fujii, T.4
  • 30
    • 0029329164 scopus 로고
    • Formation and properties of a synthetic bone composite, hydroxyapatite-collagen
    • TenHuisen K.S., Martin R.I., Klimkiewicz M., Brown P., Formation and properties of a synthetic bone composite, hydroxyapatite-collagen. J. Biomed. Mater. Res., 29, 803-810 (1995).
    • (1995) J. Biomed. Mater. Res. , vol.29 , pp. 803-810
    • Tenhuisen, K.S.1    Martin, R.I.2    Klimkiewicz, M.3    Brown, P.4
  • 31
    • 0030930156 scopus 로고    scopus 로고
    • Treatment of acute fractures with a collagen-calcium phosphate graft material
    • Chapman M.W., Bucholz R., Cornell C., Treatment of acute fractures with a collagen-calcium phosphate graft material, J. Bone Jt Surg., 79, 495-507 (1997).
    • (1997) J. Bone Jt Surg. , vol.79 , pp. 495-507
    • Chapman, M.W.1    Bucholz, R.2    Cornell, C.3
  • 32
    • 0033119387 scopus 로고    scopus 로고
    • Development of a calcium phosphate-gelatin composite as a bone substitute and its use in drug release
    • Yaylaoǧlu M.B., Korkusuz P., Ors U., Korkusuz F., Hasirci V., Development of a calcium phosphate-gelatin composite as a bone substitute and its use in drug release, Biomaterials, 20, 711-719 (1999).
    • (1999) Biomaterials , vol.20 , pp. 711-719
    • Yaylaoǧlu, M.B.1    Korkusuz, P.2    Ors, U.3    Korkusuz, F.4    Hasirci, V.5
  • 33
    • 0037086738 scopus 로고    scopus 로고
    • Bonelike apatite growth on hydroxyapatite-gelatin sponges from simulated body fluid
    • Bigi A., Boanini E., Panzavolta S., Roveri N., Rubini K., Bonelike apatite growth on hydroxyapatite-gelatin sponges from simulated body fluid, J. Biomed. Mater. Res., 59, 709-715 (2002).
    • (2002) J. Biomed. Mater. Res. , vol.59 , pp. 709-715
    • Bigi, A.1    Boanini, E.2    Panzavolta, S.3    Roveri, N.4    Rubini, K.5
  • 34
    • 0030222318 scopus 로고    scopus 로고
    • Synthesis and characterization of a new interpenetrated poly(2-hydroxyethylmethacrylate)-gelatin composite polymer
    • Santin M., Huang S.J., Iannace S., Ambrosio L., Nicolais L., Peluso G., Synthesis and characterization of a new interpenetrated poly(2- hydroxyethylmethacrylate)-gelatin composite polymer, Biomaterials, 17, 1459-1467 (1996).
    • (1996) Biomaterials , vol.17 , pp. 1459-1467
    • Santin, M.1    Huang, S.J.2    Iannace, S.3    Ambrosio, L.4    Nicolais, L.5    Peluso, G.6
  • 35
    • 0024587732 scopus 로고
    • Radiographic and microscopic evaluation of subperiosteally implanted blocks of hydroxyapatite-gelatin mixture in rabbits
    • Nagase M., Chen R.B., Asada Y, Nakajima T., Radiographic and microscopic evaluation of subperiosteally implanted blocks of hydroxyapatite-gelatin mixture in rabbits, J.Oral Maxillofac. Surg., 47, 40-45 (1989).
    • (1989) J.Oral Maxillofac. Surg. , vol.47 , pp. 40-45
    • Nagase, M.1    Chen, R.B.2    Asada, Y.3    Nakajima, T.4
  • 36
    • 0032531282 scopus 로고    scopus 로고
    • Preparation of a chitin-apatite composite by in situ precipitation onto porous scaffolds
    • Wan A.C.A., Khor E., Hastings G.W., Preparation of a chitin-apatite composite by in situ precipitation onto porous scaffolds, J. Biomed. Mater. Res., 41, 541-548 (1998).
    • (1998) J. Biomed. Mater. Res. , vol.41 , pp. 541-548
    • Wan, A.C.A.1    Khor, E.2    Hastings, G.W.3
  • 38
    • 0035869766 scopus 로고    scopus 로고
    • Nanoindentation study of interfaces between calcium phosphate and bone in an animal spinal fusion model
    • Guo L., Guo X., Leng Y., Cheng J.C.Y., Zhang X., Nanoindentation study of interfaces between calcium phosphate and bone in an animal spinal fusion model, J. Biomed. Mater. Res., 54, 554-559 (2001).
    • (2001) J. Biomed. Mater. Res. , vol.54 , pp. 554-559
    • Guo, L.1    Guo, X.2    Leng, Y.3    Cheng, J.C.Y.4    Zhang, X.5
  • 41
    • 0034666772 scopus 로고    scopus 로고
    • Low temperature formation of calcium-deficient hydroxyapatite-PLA/PLGA composites
    • Durucan C., Brown P.W., Low temperature formation of calcium-deficient hydroxyapatite-PLA/PLGA composites, J. Biomed. Mater. Res., 51, 717-725 (2000).
    • (2000) J. Biomed. Mater. Res. , vol.51 , pp. 717-725
    • Durucan, C.1    Brown, P.W.2
  • 44
    • 9844261167 scopus 로고    scopus 로고
    • Fiber-matrix interface studies on bioabsorbable composite materials for internal fixation of bone fractures, I. Raw materials evaluation and measurement of fiber-matrix interfacial adhesion
    • Slivka M.A., Chu C.C., Adisaputro I.A., Fiber-matrix interface studies on bioabsorbable composite materials for internal fixation of bone fractures, I. Raw materials evaluation and measurement of fiber-matrix interfacial adhesion, J. Biomed. Mater. Res., 36, 469-477 (1997).
    • (1997) J. Biomed. Mater. Res. , vol.36 , pp. 469-477
    • Slivka, M.A.1    Chu, C.C.2    Adisaputro, I.A.3
  • 45
    • 0032403157 scopus 로고    scopus 로고
    • Hydroxyapatite-poly ethylene composites for bone substitution, effects of ceramic particle size and morphology
    • Wang M., Joseph R., Bonfield W., Hydroxyapatite-poly ethylene composites for bone substitution, effects of ceramic particle size and morphology, Biomaterials, 19, 2357-2366 (1998).
    • (1998) Biomaterials , vol.19 , pp. 2357-2366
    • Wang, M.1    Joseph, R.2    Bonfield, W.3
  • 46
    • 0026766187 scopus 로고
    • Development of a degradable composite for orthopedic use, in vivo biomechanical and histological evaluation of two bioactive degradable composites based on the polyhydroxybutyrate polymer
    • Knowles J.C., Hastings G.W., Ohta H., Niwa S., Boeree N., Development of a degradable composite for orthopedic use, in vivo biomechanical and histological evaluation of two bioactive degradable composites based on the polyhydroxybutyrate polymer, Biomaterials, 13, 491-496 (1992).
    • (1992) Biomaterials , vol.13 , pp. 491-496
    • Knowles, J.C.1    Hastings, G.W.2    Ohta, H.3    Niwa, S.4    Boeree, N.5
  • 48
    • 0029329236 scopus 로고
    • Histological evaluation of a biodegradable polyactive®/hydroxyapatite membrane
    • Jansen J.A., de Ruijter I.E., Janssen P.T.M., Paquay Y.G.C.J., Histological evaluation of a biodegradable polyactive®/hydroxyapatite membrane, Biomaterials, 16, 819-827 (1995).
    • (1995) Biomaterials , vol.16 , pp. 819-827
    • Jansen, J.A.1    De Ruijter, I.E.2    Janssen, P.T.M.3    Paquay, Y.G.C.J.4
  • 49
    • 33645621475 scopus 로고    scopus 로고
    • Fabrication of a porous composite scaffold based on gelatin hydroxyapatite part II. Cell attachment results
    • Asgarzadeh K., Orang F., Fabrication of a porous composite scaffold based on gelatin hydroxyapatite part II. Cell attachment results, BME J., 1, 57-64 (2004).
    • (2004) BME J. , vol.1 , pp. 57-64
    • Asgarzadeh, K.1    Orang, F.2
  • 50
    • 0031365853 scopus 로고    scopus 로고
    • Porous materials for bone engineering
    • Liu D.M., Dixit V. (Eds.), Trans. Tech., Switzerland
    • Simske S.J., Ayers R.A., Bateman T.A., Porous materials for bone engineering. In: Porous Materials for Tissue Engineering. Liu D.M., Dixit V. (Eds.), Trans. Tech., Switzerland, 151-182 (1997).
    • (1997) Porous Materials for Tissue Engineering , pp. 151-182
    • Simske, S.J.1    Ayers, R.A.2    Bateman, T.A.3
  • 55
    • 33645623815 scopus 로고    scopus 로고
    • http://www.mat.chalmers.se/kurser/mpm080/lab-dmta.pdf
  • 56
    • 0033135945 scopus 로고    scopus 로고
    • Bioresorbable devices made of forged composites of hydroxyapatite (HA) particles and poly-L-lactide (PLLA), Part I. Basic characteristics
    • Shikinami Y., Okuno M., Bioresorbable devices made of forged composites of hydroxyapatite (HA) particles and poly-L-lactide (PLLA), Part I. Basic characteristics, Biomaterials, 20, 859-877 (1999).
    • (1999) Biomaterials , vol.20 , pp. 859-877
    • Shikinami, Y.1    Okuno, M.2


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