Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-hα7 cells by activating neuronal nicotinic acetylcholine receptors

Journal of Neurochemistry

Volumn 94, Issue 5, 2005, Pages 1329-1341

  Pakkanen, Jukka S ^a   Nousiainen, Heli ^a   Yli Kauhaluoma, Jari ^a   Kylänlahti, Irene ^a   Möykkynen, Tommi ^b   Korpi, Esa R ^b   Peng, Jian Hong ^c   Lukas, Ronald J ^c   Ahtee, Liisa ^a   Tuominen, Raimo K ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c Barrow Clinic   (United States)

Author keywords

Addiction; Calcium fluorometry; Nicotine; Opioid

Indexed keywords

BUNGAROTOXIN RECEPTOR; CADMIUM CHLORIDE; CALCIUM; EPIBATIDINE; MECAMYLAMINE; METHADONE; METHYLLYCACONITINE; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3; OPIATE AGONIST; RECEPTOR SUBTYPE; RYANODINE; TRITIUM; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; XESTOSPONGIN C;

ARTICLE; BINDING ASSAY; BINDING COMPETITION; BINDING SITE; CALCIUM CELL LEVEL; CELL STRAIN; CELL STRAIN SH EP1 HALPHA7; CELL STRAIN SH SY5Y; CHOLINERGIC RECEPTOR BLOCKING; CONTROLLED STUDY; CYTOFLUOROMETRY; DISSOCIATION CONSTANT; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SENSITIVITY; ENANTIOMER; HUMAN; HUMAN CELL; ION CURRENT; ISOMER; LIGAND BINDING; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RECEPTOR UPREGULATION;

ANALGESICS, OPIOID; BINDING, COMPETITIVE; CALCIUM; CELL LINE, TUMOR; FLUOROMETRY; HUMANS; INTRACELLULAR MEMBRANES; LIGANDS; METHADONE; NEURONS; NICOTINIC AGONISTS; PATCH-CLAMP TECHNIQUES; RECEPTORS, NICOTINIC; TIME FACTORS; UP-REGULATION;

EID: 24144464249     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03279.x     Document Type: Article

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