메뉴 건너뛰기




Volumn 32, Issue SUPPL. 6, 2005, Pages

Chemotherapeutic gemcitabine doublets in pancreatic carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DNA TOPOISOMERASE INHIBITOR; EXATECAN; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; LOW MOLECULAR WEIGHT HEPARIN; MARIMASTAT; MATRIX METALLOPROTEINASE INHIBITOR; OXALIPLATIN; PEMETREXED; PROTEIN FARNESYLTRANSFERASE INHIBITOR; TIPIFARNIB;

EID: 24144439324     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2005.02.005     Document Type: Article
Times cited : (11)

References (29)
  • 2
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • H.A. Burris III, M.J. Moore, J. Anderson Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer A randomized trial J Clin Oncol 15 1997 2403 2413
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Anderson, J.3
  • 3
    • 0037100983 scopus 로고    scopus 로고
    • A double-blind placebo-controlled, randomized study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
    • S.R. Bramhall, J. Schulz, J. Nemunaitis A double-blind placebo-controlled, randomized study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer Br J Cancer 87 2002 161 167
    • (2002) Br J Cancer , vol.87 , pp. 161-167
    • Bramhall, S.R.1    Schulz, J.2    Nemunaitis, J.3
  • 4
    • 0037083621 scopus 로고    scopus 로고
    • Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: A prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale
    • G. Colucci, F. Giuliani, V. Gebbia Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma A prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale Cancer 94 2002 902 910
    • (2002) Cancer , vol.94 , pp. 902-910
    • Colucci, G.1    Giuliani, F.2    Gebbia, V.3
  • 5
    • 1542358227 scopus 로고    scopus 로고
    • A phase III trial comparing gemcitabine plus cisplatin vs. gemcitabine alone in advanced pancreatic carcinoma
    • V. Heinemann, D. Quietzsch, F. Gieseler A phase III trial comparing gemcitabine plus cisplatin vs. gemcitabine alone in advanced pancreatic carcinoma Proc Am Soc Clin Oncol 22 2003 250 (abstr 1003)
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 250
    • Heinemann, V.1    Quietzsch, D.2    Gieseler, F.3
  • 6
    • 0141688333 scopus 로고    scopus 로고
    • Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • M.J. Moore, J. Hamm, J. Dancey Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas A phase III trial of the National Cancer Institute of Canada Clinical Trials Group J Clin Oncol 21 2003 3296 3302
    • (2003) J Clin Oncol , vol.21 , pp. 3296-3302
    • Moore, M.J.1    Hamm, J.2    Dancey, J.3
  • 7
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • C.M. Rocha Lima, M.R. Green, R. Rotche Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate J Clin Oncol 22 2004 3776 3783
    • (2004) J Clin Oncol , vol.22 , pp. 3776-3783
    • Rocha Lima, C.M.1    Green, M.R.2    Rotche, R.3
  • 8
    • 2342645506 scopus 로고    scopus 로고
    • Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer
    • E. Van Cutsem, H. van de Velde, P. Karasek Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer J Clin Oncol 22 2004 1430 1438
    • (2004) J Clin Oncol , vol.22 , pp. 1430-1438
    • Van Cutsem, E.1    Van De Velde, H.2    Karasek, P.3
  • 9
    • 0036682041 scopus 로고    scopus 로고
    • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
    • J.D. Berlin, P. Catalano, J.P. Thomas Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma Eastern Cooperative Oncology Group Trial E2297 J Clin Oncol 20 2002 3270 3275
    • (2002) J Clin Oncol , vol.20 , pp. 3270-3275
    • Berlin, J.D.1    Catalano, P.2    Thomas, J.P.3
  • 10
    • 0037100983 scopus 로고    scopus 로고
    • A double-blind placebo-controlled, randomized study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
    • S.R. Bramhall, J. Schulz, J. Nemunaitis A double-blind placebo-controlled, randomized study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer Br J Cancer 87 2002 161 167
    • (2002) Br J Cancer , vol.87 , pp. 161-167
    • Bramhall, S.R.1    Schulz, J.2    Nemunaitis, J.3
  • 11
    • 18744367197 scopus 로고    scopus 로고
    • Phase III results of exatecan (DX-8951f) versus gemcitabine (Gem) in chemotherapy-naïve patients with advanced pancreatic cancer (APC)
    • P. Cheverton, H. Friess, C. Andras Phase III results of exatecan (DX-8951f) versus gemcitabine (Gem) in chemotherapy-naïve patients with advanced pancreatic cancer (APC) Proc Am Soc Clin Oncol 23 2004 314s (abstr 4005)
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Cheverton, P.1    Friess, H.2    Andras, C.3
  • 12
    • 16444384413 scopus 로고    scopus 로고
    • A randomized phase III trial of DX-8951f (Exatecan Mesylate: DX) and gemcitabine (GEM) vs. gemcitabine alone in advanced pancreatic cancer (APC)
    • E.M. O'Reilly, G.K. Abou-Alfa, R. Letourneau A randomized phase III trial of DX-8951f (Exatecan Mesylate: DX) and gemcitabine (GEM) vs. gemcitabine alone in advanced pancreatic cancer (APC) Proc Am Soc Clin Oncol 23 2004 315s (abstr 4006)
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • O'Reilly, E.M.1    Abou-Alfa, G.K.2    Letourneau, R.3
  • 14
    • 16444372799 scopus 로고    scopus 로고
    • A randomized phase III study comparing gemcitabine + pemetrexed versus gemcitabine in patients with locally advanced and metastatic pancreas cancer
    • D.A. Richards, H.L. Kindler, H. Oettle A randomized phase III study comparing gemcitabine + pemetrexed versus gemcitabine in patients with locally advanced and metastatic pancreas cancer Proc Am Soc Clin Oncol 23 2004 315s (abstr 4007)
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Richards, D.A.1    Kindler, H.L.2    Oettle, H.3
  • 15
    • 16444383237 scopus 로고    scopus 로고
    • GemOx (Gemcitabine + Oxaliplatin) versus Gem (Gemcitabine) in non resectable pancreatic adenocarcinoma: Final results of the GERCOR/GISCAD Intergroup Phase III
    • C. Louvet, R. Lablanca, P. Hammel GemOx (Gemcitabine + Oxaliplatin) versus Gem (Gemcitabine) in non resectable pancreatic adenocarcinoma Final results of the GERCOR/GISCAD Intergroup Phase III Proc Am Soc Clin Oncol 23 2004 315s (abstr 4008)
    • (2004) Proc Am Soc Clin Oncol , vol.23
    • Louvet, C.1    Lablanca, R.2    Hammel, P.3
  • 16
    • 3042517023 scopus 로고    scopus 로고
    • February 5, Consumer Drug Information - Alimta.
    • U.S. Food and Drug Administration, Department of Health and Human Services. FDA News February 5, 2004; Consumer Drug Information - Alimta. Available at: http:/www.fda.gov/cder/consumerinfo/DRUGINFO/Alimta.htm. (accessed Nov 2, 2004)
    • (2004) FDA News
  • 17
    • 0033981350 scopus 로고    scopus 로고
    • Phase II study of the multi-targeted antifolate LY231514 (ALIMTA, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer
    • K.D. Miller, J. Picus, C. Blanke Phase II study of the multi-targeted antifolate LY231514 (ALIMTA, MTA, pemetrexed disodium) in patients with advanced pancreatic cancer Ann Oncol 11 2000 101 103
    • (2000) Ann Oncol , vol.11 , pp. 101-103
    • Miller, K.D.1    Picus, J.2    Blanke, C.3
  • 18
    • 0037102999 scopus 로고    scopus 로고
    • The pemetrexed/gemcitabine combination in pancreatic cancer
    • H.L. Kindler The pemetrexed/gemcitabine combination in pancreatic cancer Cancer 95 suppl 4 2002 928 932
    • (2002) Cancer , vol.95 , Issue.4 SUPPL. , pp. 928-932
    • Kindler, H.L.1
  • 19
    • 0037087787 scopus 로고    scopus 로고
    • Gemcitabine combined with oxaliplatin in advanced pancreatic adenocarcinoma: Final results of a GERCOR multicenter phase II study
    • C. Louvet, T. Andre, G. Lledo Gemcitabine combined with oxaliplatin in advanced pancreatic adenocarcinoma Final results of a GERCOR multicenter phase II study J Clin Oncol 20 2002 1512 1518
    • (2002) J Clin Oncol , vol.20 , pp. 1512-1518
    • Louvet, C.1    Andre, T.2    Lledo, G.3
  • 20
    • 0025089191 scopus 로고
    • Pharmacologically directed design of the dose rate and schedule of 2', 2'-difluorodeoxycytidine (gemcitabine) administration in leukemia
    • R. Grunewald, H. Kantarjian, M.J. Keating Pharmacologically directed design of the dose rate and schedule of 2', 2'-difluorodeoxycytidine (gemcitabine) administration in leukemia Cancer Res 50 1990 6823 6826
    • (1990) Cancer Res , vol.50 , pp. 6823-6826
    • Grunewald, R.1    Kantarjian, H.2    Keating, M.J.3
  • 21
    • 0025978216 scopus 로고
    • A phase I clinical, plasma, and cellular pharmacology study of gemcitabine
    • J.L. Abbruzzese, R. Grunewald, E.A. Weeks A phase I clinical, plasma, and cellular pharmacology study of gemcitabine J Clin Oncol 9 1991 491 498
    • (1991) J Clin Oncol , vol.9 , pp. 491-498
    • Abbruzzese, J.L.1    Grunewald, R.2    Weeks, E.A.3
  • 22
    • 0142121290 scopus 로고    scopus 로고
    • Randomized phase II comparison of dose-intense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
    • M. Tempero, W. Plunkett, V. Ruiz Van Haperen Randomized phase II comparison of dose-intense gemcitabine Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma J Clin Oncol 21 2003 3383 3384
    • (2003) J Clin Oncol , vol.21 , pp. 3383-3384
    • Tempero, M.1    Plunkett, W.2    Ruiz Van Haperen, V.3
  • 23
    • 2442451440 scopus 로고    scopus 로고
    • Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines
    • E. Giovannetti, V. Mey, R. Danesi Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines Clin Cancer Res 10 2004 2936 2943
    • (2004) Clin Cancer Res , vol.10 , pp. 2936-2943
    • Giovannetti, E.1    Mey, V.2    Danesi, R.3
  • 24
    • 4243990605 scopus 로고    scopus 로고
    • Biochemically synergistic chemotherapy for advanced pancreatic cancer (PC)
    • R.L. Fine, W. Sherman, J. Chabot Biochemically synergistic chemotherapy for advanced pancreatic cancer (PC) Proc Am Soc Clin Oncol 21 2002 144A (abstr 575)
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Fine, R.L.1    Sherman, W.2    Chabot, J.3
  • 25
    • 7944234512 scopus 로고    scopus 로고
    • Advances in the genetic screening, work-up, and treatment of pancreatic cancer
    • H. Frucht, P.D. Stevens, D.R. Fogelman Advances in the genetic screening, work-up, and treatment of pancreatic cancer Curr Treat Options Gastroenterol 7 2004 343 354
    • (2004) Curr Treat Options Gastroenterol , vol.7 , pp. 343-354
    • Frucht, H.1    Stevens, P.D.2    Fogelman, D.R.3
  • 26
    • 27644460508 scopus 로고    scopus 로고
    • Erlotinib improves survival when added to gemcitabine in patients with advanced pancreatic cancer. a phase III trial of the National Cancer Institute of Canada Clinical Trials Group [NCIC-CTG]
    • M.J. Moore, D. Goldstein, J. Hamm Erlotinib improves survival when added to gemcitabine in patients with advanced pancreatic cancer. A phase III trial of the National Cancer Institute of Canada Clinical Trials Group [NCIC-CTG] Proc Am Soc Clin Oncol 23 2005 16S (abstr 1)
    • (2005) Proc Am Soc Clin Oncol , vol.23
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 27
    • 0017347011 scopus 로고
    • Troussean syndrome and other manifestations of chronic disseminated coagulopathy in patients with neoplasms: Clinical, pathophysiologic and therapeutic features
    • G.S. Sack, J. Levin, W.R. Bell Troussean syndrome and other manifestations of chronic disseminated coagulopathy in patients with neoplasms Clinical, pathophysiologic and therapeutic features Medicine 56 1977 1 37
    • (1977) Medicine , vol.56 , pp. 1-37
    • Sack, G.S.1    Levin, J.2    Bell, W.R.3
  • 28
    • 0242469234 scopus 로고    scopus 로고
    • Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight
    • A.A. Khorana, A. Sahni, O.D. Altand Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight Arterioscler Thromb Vasc Biol 23 2003 2110 2115
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 2110-2115
    • Khorana, A.A.1    Sahni, A.2    Altand, O.D.3
  • 29
    • 0027407397 scopus 로고
    • Heparin and angiogenesis: A low-molecular-weight fraction inhibits and a high-molecular-weight fraction stimulates angiogenesis systemically
    • K. Norrby Heparin and angiogenesis A low-molecular-weight fraction inhibits and a high-molecular-weight fraction stimulates angiogenesis systemically Haemostasis 23 suppl 1 1993 141 149
    • (1993) Haemostasis , vol.23 , Issue.1 SUPPL. , pp. 141-149
    • Norrby, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.