Moyamoya syndrome associated with hemolytic anemia due to Hb Alesha

Journal of Pediatric Hematology/Oncology

Volumn 27, Issue 8, 2005, Pages 436-440

  Brockmann, Knut ^a,e   Stolpe, Stephan ^a   Fels, Carsten ^a   Khan, Nadia ^b   Kulozik, Andreas E ^c   Pekrun, Arnulf ^a,d  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d KLINIKUM BREMEN MITTE   (Germany)

^e Department of Pediatrics and Neuropediatrics   (Germany)

Author keywords

Hb Alesha; Hemoglobinopathy; Hemolytic anemia; Moyamoya angiopathy; Transient ischemic attacks

Indexed keywords

BETA GLOBIN; HEMOGLOBIN; HEMOGLOBIN ALESHA; METHIONINE; OXYGEN; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; BLOOD CELL COUNT; BRAIN ANGIOGRAPHY; BYPASS SURGERY; CASE REPORT; CHILD; DOPPLER ECHOGRAPHY; ELECTROENCEPHALOGRAPHY; ELECTROPHORESIS; FEMALE; GENE MUTATION; HEMOLYTIC ANEMIA; HUMAN; HYPERTENSION; INTERNAL CAROTID ARTERY OCCLUSION; MAGNETIC RESONANCE ANGIOGRAPHY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOYAMOYA DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; PRIORITY JOURNAL; REPERFUSION; SPLENECTOMY; SPLENOMEGALY; TRANSFUSION; TRANSIENT ISCHEMIC ATTACK; VASCULAR DISEASE;

ANEMIA, HEMOLYTIC; CHILD; COGNITION DISORDERS; ELECTROENCEPHALOGRAPHY; FEMALE; HEMOGLOBINS, ABNORMAL; HUMANS; HYPOXIA, BRAIN; MAGNETIC RESONANCE ANGIOGRAPHY; MAGNETIC RESONANCE IMAGING; MOYAMOYA DISEASE;

EID: 24144436910     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mph.0000175409.21342.ea     Document Type: Article

References (16)

1. Yonekawa Y, Goto Y, Ogata N. Moyamoya disease: diagnosis, treatment and recent achievement. In: Barnett HJM, Mohr JP, Stein BM, Yatsu FM, eds. Stroke: pathophysiology, diagnosis and management, 2nd ed. New York, NY: Churchill Livingstone, 1992:721-748.
2. Khan N, Schinzel A, Shuknecht B, et al. Moyamoya angiopathy with dolichoectatic internal carotid arteries, patent ductus arteriosus and pupillary dysfunction: a new genetic syndrome? Eur Neurol. 2004;51:72-77.
3. Kirkham FJ, DeBaun MR. Stroke in children with sickle cell disease. Curr Treat Options Neurol. 2004;6:357-375.
4. Holz A, Woldenberg R, Miller D, et al. Moyamoya disease in a patient with hereditary spherocytosis. Pediatr Radiol. 1998;28:95-97.
5. Mukherjee A. Moyamoya disease and beta-thalassemia. J Assoc Physicians India. 1995;43:710-711.
6. Khan N, Schuknecht B. Boltshauser E, et al. Moyamoya disease and Moyamoya syndrome: experience in Europe; choice of revascularisation procedures. Acta Neurochir (Wien). 2003;145:1061-1071.
7. Kodama N, Aoki Y. Hiraga H, et al. Electroencephalographic findings in children with moyamoya disease. Arch Neurol. 1979;36:16-19.
8. Kulozik AE. Haemoglobin variants and the rarer haemoglobin disorders. In: Lilleyman J, Hann I, Blanchette V, eds. Pediatric hematology. London: Churchill Livingstone, 1999.
9. Molchanova TP, Postnikov Yu V, Pobedimskaya DD, et al. Hb Alesha or alpha 2 beta (2)67(E11)Val→Met: a new unstable haemoglobin variant identified through sequencing of amplified DNA. Hemoglobin. 1993;17:217-225.
10. Stockman JA, Nigro MA, Mishkin MM, et al. Occlusion of large cerebral vessels in sickle-cell anemia. N Engl J Med. 1972;287:846-849.
11. Dobson SR, Holden KR, Nieten PJ, et al. Moyamoya syndrome in childhood sickle cell disease: a predictive factor for recurrent cerebrovascular events. Blood. 2002;99:3144-3150.
12. Stuart MJ, Setty BN. Hemostatic alterations in sickle cell disease: relationships to disease pathophysiology. Pediatr Pathol Mol Med. 2001;20:27-46.
13. Kalinyak KA, Morris C, Ball WS, et al. Bone marrow transplantation in a young child with sickle cell anemia. Am J Hematol. 1995;48:256-261.
14. Setty BN, Stuart MJ, Dampier C, et al. Hypoxaemia in sickle cell disease: biomarker modulation and relevance to pathophysiology. Lancet. 2003;362:1450-1455.
15. Shreeniwas R, Koga S, Karakurum M, et al. Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface. J Clin Invest. 1992;90:2333-2339.
16. Phelan MW, Faller DV. Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells. J Cell Physiol. 1996;167:469-476.