Linezolid-a new option for treating gram-positive infections

ONCOLOGY

Volumn 14, Issue 8 SUPPL. 6, 2000, Pages 23-29

  Baits, Donald H ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAMIDE DERIVATIVE; ANTIINFECTIVE AGENT; LINEZOLID; OXAZOLIDINONE DERIVATIVE;

ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; CROSS INFECTION; HUMAN; IMMUNE DEFICIENCY; ORAL DRUG ADMINISTRATION; OUTPATIENT; PATHOLOGY; REVIEW; STAPHYLOCOCCUS INFECTION;

ACETAMIDES; ADMINISTRATION, ORAL; ANTI-INFECTIVE AGENTS; CROSS INFECTION; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; IMMUNOCOMPROMISED HOST; OUTPATIENTS; OXAZOLIDINONES; STAPHYLOCOCCAL INFECTIONS; VANCOMYCIN RESISTANCE;

EID: 24044504112     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Jones RN, Low DE, Pfaller MA: Epidemiologie trends in nosocomial and community-acquired infections due to antibioticresistant gram-positive bacteria: The role of streptogramins and other newer compounds. Diagn Microbiol Infect Dis 33:101-112, 1999.
2. Noskin GA, Siddiqui F, Stosor V, et al: In vitro activities of Linezolid against important gram-positive bacterial pathogens including vancomycin-resistant enterococci. Antimicrob Agents Chemother 43:2059-2062, 1999.
3. Shinabarger DL, Marotti KR, Murray RW, et al: Mechanism of action of oxazolidinones: Effects of linezolid and eperezolid on translation reactions. Antimicrob Agents Chemother 41:2132-2136, 1997.
4. Matassova NB, Rodnina MV, Endermann R, et al: Ribosomal RNA is the target for oxazolidinones: A novel class of translational inhibitors. RNA 5:939-946, 1999.
5. Swaney SM, Aoki H, Ganoza MC, Shinabarger DL: The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria. Antimicrob Agents Chemother 42:3251-3255, 1998.