Effects of phencyclidine on acoustic startle and prepulse inhibition in neuronal nitric oxide synthase deficient mice

European Neuropsychopharmacology

Volumn 15, Issue 5, 2005, Pages 587-590

  Klamer, Daniel ^a   Engel, Jörgen A ^a   Svensson, Lennart ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Mice; Nitric oxide synthase; Phencyclidine; Prepulse inhibition; Schizophrenia

Indexed keywords

NEURONAL NITRIC OXIDE SYNTHASE; PHENCYCLIDINE;

ACOUSTIC REFLEX; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIVITY; ENZYME DEFICIENCY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; STARTLE REFLEX;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HETEROZYGOTE; HOMOZYGOTE; MALE; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; PHENCYCLIDINE; STARTLE REACTION;

EID: 24044483855     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2005.02.002     Document Type: Article

References (24)

1. V.P. Bakshi, N.R. Swerdlow, and M.A. Geyer Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response J. Pharmacol. Exp. Ther. 271 1994 787 794
2. D.L. Braff, N.R. Swerdlow, and M.A. Geyer Symptom correlates of prepulse inhibition deficits in male schizophrenic patients Am. J. Psychiatry 156 1999 596 602
3. A. Carlsson, L.O. Hansson, N. Waters, and M.L. Carlsson A glutamatergic deficiency model of schizophrenia Br. J. Psychiatry 1999 2 6 (Suppl.)
4. S.C. Dulawa, and M.A. Geyer Psychopharmacology of prepulse inhibition in mice Chin. J. Physiol. 39 1996 139 146
5. J.M. ffrench-Mullen, M.A. Rogawski, and J.L. Barker Phencyclidine at low concentrations selectively blocks the sustained but not the transient voltage-dependent potassium current in cultured hippocampal neurons Neurosci. Lett. 88 1988 325 330
6. M.A. Geyer Assessing prepulse inhibition of startle in wild-type and knockout mice Psychopharmacology (Berl.) 147 1999 11 13
7. M.A. Geyer, K. Krebs-Thomson, D.L. Braff, and N.R. Swerdlow Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review Psychopharmacology (Berl.) 156 2001 117 154
8. H.S. Hoffman, and J.R. Ison Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system process sensory input Psychol. Rev. 2 1980 175 189
9. C. Johansson, D.M. Jackson, and L. Svensson The atypical antipsychotic, remoxipride, blocks phencyclidine-induced disruption of prepulse inhibition in the rat Psychopharmacology (Berl.) 116 1994 437 442
10. C. Johansson, D.M. Jackson, and L. Svensson Nitric oxide synthase inhibition blocks phencyclidine-induced behavioural effects on prepulse inhibition and locomotor activity in the rat Psychopharmacology (Berl.) 131 1997 167 173
11. C. Johansson, O. Magnusson, A.M. Deveney, D.M. Jackson, J. Zhang, J.A. Engel, and L. Svensson The nitric oxide synthase inhibitor, l-NAME, blocks certain phencyclidine-induced but not d-amphetamine-induced effects on behaviour and brain biochemistry in the rat Prog. Neuro-Psychopharmacol. Biol. Psychiatry 22 1998 1341 1360
12. C. Johansson, A.M. Deveney, D. Reif, and D.M. Jackson The neuronal selective nitric oxide inhibitor AR-R 17477, blocks some effects of phencyclidine, while having no observable behavioural effects when given alone Pharmacol. Toxicol. 84 1999 226 233
13. S. Kapur, and P. Seeman NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D(2) and serotonin 5-HT(2)receptors-implications for models of schizophrenia Mol. Psychiatry 7 2002 837 844
14. V.A. Keith, R.S. Mansbach, and M.A. Geyer Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle Biol. Psychiatry 30 1991 557 566
15. D. Klamer, J.A. Engel, and L. Svensson The nitric oxide synthase inhibitor, l-NAME, blocks phencyclidine-induced disruption of prepulse inhibition in mice Psychopharmacology (Berl.) 156 2001 182 186
16. G-propyl-l-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice Eur. J. Pharmacol. 503 2004 103 107
17. D. Klamer, E. Palsson, A. Revesz, J.A. Engel, and L. Svensson Habituation of acoustic startle is disrupted by psychotomimetic drugs: differential dependence on dopaminergic and nitric oxide modulatory mechanisms Psychopharmacology (Berl) 176 2004 440 450
18. Y.M. Kokoz, A.E. Alekseev, A.A. Povzun, A.F. Korystova, and H. Peres-Saad Anaesthetic phencyclidine, blocker of the ATP-sensitive potassium channels FEBS Lett. 337 1994 277 280
19. W. Perry, and D.L. Braff Information-processing deficits and thought disorder in schizophrenia Am. J. Psychiatry 151 1994 363 367
20. 2+ Am. J. Physiol. 271 1996 H696 H705
21. R.B. Rothman, A.A. Reid, J.A. Monn, A.E. Jacobson, and K.C. Rice The psychotomimetic drug phencyclidine labels two high affinity binding sites in guinea pig brain: evidence for N-methyl-d-aspartate-coupled and dopamine reuptake carrier-associated phencyclidine binding sites Mol. Pharmacol. 36 1989 887 896
22. S.A. Thornberg, and S.R. Saklad A review of NMDA receptors and the phencyclidine model of schizophrenia Pharmacotherapy 16 1996 82 93
23. E. Weber, M. Sonders, M. Quarum, S. McLean, S. Pou, and J.F. Keana 1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs Proc. Natl. Acad. Sci. U. S. A. 83 1986 8784 8788
24. J.L. Wiley Nitric oxide synthase inhibitors attenuate phencyclidine-induced disruption of prepulse inhibition Neuropsychopharmacology 19 1998 86 94