Cell-specific expression of the epm1 (cystatin B) gene in developing rat cerebellum

Neurobiology of Disease

Volumn 20, Issue 1, 2005, Pages 104-114

  Riccio, Massimo ^a   Santi, Spartaco ^a   Dembic, Maja ^a   Di Giaimo, Rossella ^b   Cipollini, Elena ^c   Costantino Ceccarini, Elvira ^d   Ambrosetti, Davide ^c   Maraldi, Nadir M ^a   Melli, Marialuisa ^c  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d CNR   (Italy)

Author keywords

Cell specific gene expression; Co localization; Cystatin B; Developing cerebellum; EPM1; Glial and neuronal lineage

Indexed keywords

CYSTATIN B; MYELIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN DEVELOPMENT; CEREBELLUM; DENTATE GYRUS; DEVELOPMENTAL STAGE; DOWN REGULATION; FIBER; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE LOCATION; GLIA CELL; HIPPOCAMPUS; NERVE CELL; NERVOUS SYSTEM; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURKINJE CELL; RAT; STEM CELL; SYNTHESIS;

AGING; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CEREBELLUM; CYSTATINS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; NERVE FIBERS, MYELINATED; NEUROFILAMENT PROTEINS; NEUROGLIA; NEUROPEPTIDES; OLIGODENDROGLIA; PURKINJE CELLS; RATS; RATS, SPRAGUE-DAWLEY; SPECTRIN; STEM CELLS;

EID: 24044468070     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.02.012     Document Type: Article

References (42)

1. K. Alakurtti, K. Virtaneva, T. Joensuu, J.J. Palvimo, and A.E. Lehesjoki Characterization of the cystatin B gene promoter harboring the dodecamer repeat expanded in progressive myoclonus epilepsy, EPM1 Gene 242 2000 65 73
2. A. Bignami, and D. Dahl Differentiation of astrocytes in the cerebellar cortex and the pyramidal tracts of the newborn rat. An immunofluorescence study with antibodies to a protein specific to astrocytes Brain Res. 49 1973 393 402
3. F. Blasi, A. Ciarrocchi, A. Luddi, M. Strazza, M. Riccio, S. Santi, R. Arcone, C. Pietropaolo, R. D'Angelo, E. Costantino-Ceccarini, and M. Melli Stage specific gene expression in early differentiating oligodendrocytes Glia 39 2002 114 123
4. W. Bode, and R. Huber Structural basis of the endoproteinase-protein inhibitor interaction Biochim. Biophys. Acta 1477 2000 241 252
5. K. Brannvall, H. Hjelm, L. Korhonen, U. Lahtinen, A.E. Lehesjoki, and D. Lindholm Cystatin-B is expressed by neural stem cells and by differentiated neurons and astrocytes Biochem. Biophys. Res. Commun. 22 2003 369 374
6. M.R. Dawson, A. Polito, J.M. Levine, and R. Reynolds NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS Mol. Cell. Neurosci. 24 2003 476 488
7. R. Di Giaimo, M. Riccio, S. Santi, C. Galeotti, D.C. Ambrosetti, and M. Melli New insights into the molecular basis of progressive myoclonus epilepsy: a multiprotein complex with cystatin B Hum. Mol. Genet. 11 2002 2941 2950
8. F. Doetsch, J.M. Garcia-Verdugo, and A. Alvarez-Buylla Regeneration of a germinal layer in the adult mammalian brain Proc. Natl. Acad. Sci. U. S. A. 96 1999 11619 11624
9. C.L. Dou, and J.M. Levine Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan J. Neurosci. 14 1994 7616 7628
10. C.L. Dou, and J.M. Levine Identification of a neuronal cell surface receptor for a growth inhibitory chondroitin sulphate proteoglycan (NG2) J. Neurochem. 68 1997 1021 1030
11. G. Drewes, A. Ebneth, and E.M. Mandelkow MAPs, MARKs and microtubule dynamics Trends Biochem. Sci. 23 1998 307 311
12. R. Eldridge, M. Ljvanainen, R. Stern, T. Koerber, and B.J. Wilder "Baltic" myoclonus epilepsy: hereditary disorder of childhood made worse by phenytoin Lancet 2 1983 838 842
13. L. Feng, and N. Heintz Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element Development 121 1995 1719 1730
14. L. Feng, M.E. Hatten, and N. Heintz Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS Neuron 12 1994 895 908
15. Y. Giménez, M. Ribotta, F. Langa, V. Menet, and A. Privat Comparative anatomy of the cerebellar cortex in mice lacking vimentin, GFAP, and both vimentin and GFAP Glia 31 2000 69 83
16. M. Habib, J. Roger, R. Khalil, J.F. Pellissier, M. Bureau, G. Boudouresques, and F. Delpuech Progressive degenerative myoclonic epilepsy. Systematized olivo-cerebellar lesions Rev. Neurol. 141 1985 274 288
17. L.L. Jones, Y. Yamaguchi, W.B. Stallcup, and M.H. Tuszynski NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors J. Neurosci. 22 2002 2792 2803
18. R.G. Lafreniere, D.L. Rochefort, N. Chretien, J.M. Rommens, J.I. Cochius, R. Kalviainen, U. Nousiainen, G. Patry, K. Farrell, B. Soderfeldt, A. Federico, B.R. Hale, O.H. Cossio, T. Sorensen, M.A. Pouliot, T. Kmiec, P. Uldall, J. Janszky, M.R. Pranzatelli, F. Andermann, E. Andermann, and G.A. Rouleau Unstable insertion in the 5′ flanking region of the cystatin B gene is the most common mutation in progressive myoclonus epilepsy type 1, EPM1 Nat. Genet. 15 1997 298 302
19. M.D. Lalioti, H.S. Scott, C. Baresi, C. Dossier, A. Bottani, M.A. Morris, A. Malafosse, and S.E. Antonarakis Dodecamer repest expansion in cystatin B gene in progressive myoclonus epilepsy Nature 386 1997 847 851
20. M.D. Lalioti, H.S. Scott, and S.E. Antonarakis Altered spacing of promoter elements due to the dodecamer repeat expansion contributes to reduced expression of the cystatin B gene in EPM1 Hum. Mol. Genet. 8 1999 1791 1798
21. M.D. Lalioti, S.E. Antonarakis, and H.S. Scott The epilepsy, the protease inhibitor and the dodecamer: progressive myoclonus epilepsy, cystatin B and a 12-mer repeat expansion Cytogenet. Genome Res. 100 2003 213 223
22. A.E. Lehesjoki Molecular background of progressive myoclonus epilepsy EMBO J. 22 2003 3473 3478
23. 1H MRS study Neurology 58 2002 1686 1689
24. F.A. McMorris Cyclic AMP induction of the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphohydrolase in rat oligodendrocytes J. Neurochem. 41 1983 506 515
25. T.C. Nag, and S. Wadhwa Calbindin immunoreactivity in the developing and adult human cerebellum J. Chem. Neuroanat. 17 1999 1 12
26. R.S. Ozer, and S. Halpain Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton Mol. Biol. Cell 11 2000 3573 3587
27. J.G. Parnavelas, and B. Nadarajah Radial glial cells. Are they really glia? Neuron 31 2001 881 884
28. L.A. Pennacchio, and R.M. Myers Isolation and characterization of the mouse cystatin B gene Genome Res. 6 1996 1103 1109
29. L.A. Pennacchio, A.E. Lehesjoki, N.E. Stone, V.L. Willour, K. Virtaneva, J. Miao, E. D'Amato, L. Ramirez, M. Faham, M. Koskiniemi, J.A. Warrington, R. Norio, A. de la Chapelle, D.R. Cox, and R.M. Myers Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1) Science 271 1996 1731 1734
30. L.A. Pennacchio, D.M. Bouley, K.M. Higgins, M.P. Scott, J.L. Noebels, and R.M. Myers Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice Nat. Genet. 20 1998 251 258
31. D.W. Raible, and F.A. McMorris Oligodendrocyte differentiation and progenitor cell proliferation are independently regulated by cyclic AMP J. Neurosci. Res. 34 1993 287 294
32. R. Reynolds, E.M. Carey, and N. Herschkowitz Immunohistochemical localization of myelin basic protein and 2′,3′-cyclic nucleotide 3′-phosphohydrolase in flattened membrane expansions produced by cultured oligodendrocytes Neuroscience 28 1989 181 188
33. M. Riccio, R. Di Giaimo, S. Pianetti, P.P. Palmieri, M. Melli, and S. Santi Nuclear localization of cystatin B, the cathepsin inhibitor implicated in myoclonous epilepsy (EPM1) Exp. Cell Res. 262 2001 84 94
34. M. Riccio, M. Dembic, C. Cinti, and S. Santi Multifluorescence labeling and colocalization analyses A. Giordano G. Romano Methods in Molecular Biology: Cell Cycle Control and Dysregulation Protocols vol. 285 2004 Humana Press Inc. NY 171 177
35. R. Rinne, P. Saukko, M. Jarvinen, and A.E. Lehesjoki Reduced cystatin B activity correlates with enhanced cathepsin activity in progressive myoclonus epilepsy Ann. Med. 34 2002 380 385
36. J. Sambrook, E.F. Fritsh, and T. Maniatis Molecular Cloning: A Laboratory Manual 1989 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
37. P. Shannon, L.A. Pennacchio, M.K. Houseweart, B.A. Minassian, and R.M. Myers Neuropathological changes in a mouse model of progressive myoclonus epilepsy: cystatin B deficiency and Unverricht-Lundborg disease J. Neuropathol. Exp. Neurol. 61 2002 1085 1091
38. G. Tabellini, R. Bortul, S. Santi, M. Riccio, G. Baldini, A. Cappellini, A.M. Billi, R. Berezney, A. Ruggeri, L. Cocco, and A.M. Martelli Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus Exp. Cell Res. 287 2003 143 154
39. K. Virtaneva, E. D'Amato, J. Miao, M. Koskiniemi, R. Norio, G. Avanzini, S. Franceschetti, R. Michelucci, C.A. Tassinari, S. Omer, L.A. Pennacchio, R.M. Myers, J.L. Dieguez-Lucena, R. Krahe, A. de la Chapelle, and A.E. Lehesjoki Unstable minisatellite expansion causing recessively inherited myoclonus epilepsy, EPM1 Nat. Genet. 15 1997 393 396
40. K. Virtaneva, L. Paulin, R. Krahe, A. de la Chapelle, and A.E. Lehesjoki The minisatellite expansion mutation in EPM1: resolution of an initial discrepancy. Mutatations in brief no. 186 Hum. Mutat. 12 1998 218 (Online)
41. A. Weyer, and K. Schilling Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum J. Neurosci. Res. 73 2003 400 409
42. K. Yamada, and M. Watanabe Cytodifferentiation of Bergmann glia and its relationship with Purkinje cells Anat. Sci. Int. 77 2002 94 108