Cloning and characterization of a novel immunogenic protein 3 (NIP3) from Brugia malayi by immuno screening of a phage-display cDNA expression library

Parasitology Research

Volumn 97, Issue 1, 2005, Pages 49-58

  Gnanasekar, Munirathinam ^a   Padmavathi, Balumuri ^a   Ramaswamy, Kalyanasundaram ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Biopanning; Brugia malayi; EN; NIP3; Phage display

Indexed keywords

COMPLEMENTARY DNA; DNA; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; MUCIN; PROTEIN BNIP3;

ANCYLOSTOMA CANINUM; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BACTERIOPHAGE; BLOOD SAMPLING; BRUGIA MALAYI; CONTROLLED STUDY; DNA LIBRARY; DNA SCREENING; GENE; GENE INSERTION SEQUENCE; GENETIC DATABASE; HAEMONCHUS CONTORTUS; IMMUNOGENICITY; MALE; MOLECULAR CLONING; MOUSE; NEMATODE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCHOCERCA VOLVULUS; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRONGYLOIDES STERCORALIS; TELADORSAGIA CIRCUMCINCTA;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BRUGIA MALAYI; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; GENE LIBRARY; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN G; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PHOSPHORYLATION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

ANCYLOSTOMA CANINUM; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; HAEMONCHUS CONTORTUS; NEMATODA; ONCHOCERCA VOLVULUS; STRONGYLOIDES STERCORALIS; TELADORSAGIA CIRCUMCINCTA;

EID: 24044458590     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-005-1375-x     Document Type: Article

References (21)

1. Atmadja AK, Atkinson R, Sartono E, Partono F, Yazdanbakhsh M, Maizels RM (1995) Differential decline in filarial-specific IgG1, IgG4, and IgE antibodies in Brugia malayi-infected patients after diethylcarbamazine chemotherapy. J Infect Dis 172:1567-1572
2. Crameri R, Jaussi R, Menz G, Blaser K (1994) Display of expression products of cDNA libraries on phage surfaces. A versatile screening system for selective isolation of genes by specific gene-product/ligand interaction. Eur J Biochem 226:53-58
3. Folgori A, Tafi R, Meola A, Felici F, Galfre G, Cortese R, Monaci P, Nicosia A (1994) A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. Embo J 13:2236-2243
4. Frank GR, Tripp CA, Grieve RB (1996) Molecular cloning of a developmentally regulated protein isolated from excretory-secretory products of larval Dirofilaria immitis. Mol Biochem Parasitol 75:231-240
5. Germaschewski V, Murray K (1996) Identification of polyclonal serum specificities with phage-display libraries. J Virol Methods 58:21-32
6. Gnanasekar M, Rao KV, He YX, Mishra PK, Kaliraj P, Ramaswamy K (2004) A novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi. Infect Immun 72:4707-4715
7. Helmy H, Weil GJ, Faris R, Gad AM, Chandrashekar R, Ashour A, Ramzy RM (2000) Human antibody responses to Wuchereria bancrofti infective larvae. Parasite Immunol 22:89-96
8. Kurniawan A, Yazdanbakhsh M, Van Ree R, Aalberse R, Selkirk ME, Partono F, Maizels RM (1993) Differential expression of IgE and IgG4 specific antibody responses in asymptomatic and chronic human filariasis. J Immunol 150:3941-3950
9. Kurniawan-Atmadja A, Sartono E, Partono F, Yazdanbakhsh M, Maizels RM (1998a) Antibody responses to filarial infective larvae are not dominated by the IgG4 isotype. Parasite Immunol 20:9-17
10. Kurniawan-Atmadja A, Sartono E, Partono F, Yazdanbakhsh M, Maizels RM (1998b) Specificity of predominant IgG4 antibodies to adult and microfilarial stages of Brugia malayi. Parasite Immunol 20:155-162
11. Lalitha P, Ravichandran M, Suba S, Kaliraj P, Narayanan RB, Jayaraman K (1998) Quantitative assessment of circulating antigens in human lymphatic filariasis: a field evaluation of monoclonal antibody-based ELISA using blood collected on filter strips. Trop Med Int Health 3:41-45
12. Lalitha P, Eswaran D, Gnanasekar M, Rao KV, Narayanan RB, Scott A, Nutman T, Kaliraj P (2002) Development of antigen detection ELISA for the diagnosis of brugian and bancroftian filariasis using antibodies to recombinant filarial antigens Bm-SXP-1 and Wb-SXP-1. Microbiol Immunol 46:327-332
13. Lizotte-Waniewski M, Tawe W, Guiliano DB, Lu W, Liu J, Williams SA, Lustigman S (2000) Identification of potential vaccine and drug target candidates by expressed sequence tag analysis and immunoscreening of Onchocerca volvulus larval cDNA libraries. Infect Immun 68:3491-3501
14. Mohanty MC, Satapathy AK, Sahoo PK, Ravindran B (2001) Human bancroftian filariasis - a role for antibodies to parasite carbohydrates. Clin Exp Immunol 124:54-61
15. Molyneux D (2003) Lymphatic filariasis (Elephantiasis) elimination: a public health success and development opportunity. Filaria J 2:13
16. Peralta ME, Schmitz KA, Rajan TV (1999) Failure of highly immunogenic filarial proteins to provide host-protective immunity. Exp Parasitol 91:334-340
17. Rao KV, Eswaran D, Ravi V, Gnanasekar M, Narayanan RB, Kaliraj P, Jayaraman K, Marson A, Raghavan N, Scott AL (2000) The Wuchereria bancrofti orthologue of Brugia malayi SXP1 and the diagnosis of bancroftian filariasis. Mol Biochem Parasitol 107:71-80
18. Rathaur S, Fischer P, Domagalski M, Walter RD, Liebau E (2003) Brugia malayi and Wuchereria bancrofti: gene comparison and recombinant expression of pi-class related glutathione S-transferases. Exp Parasitol103:177-181
19. Ravindran B, Satapathy AK, Sahoo PK, Babu Geddam JJ (2000) Protective immunity in human Bancroftian filariasis: inverse relationship between antibodies to microfilarial sheath and circulating filarial antigens. Parasite Immunol 22:633-637
20. Smith GP (1985) Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 228:1315-1317
21. Somers VA, Brandwijk RJ, Joosten B, Moerkerk PT, Arenas JW, Menheere P, Pieterse WO, Claessen A, Scheper RJ, Hoogenboom HR, Hufton SE (2002) A panel of candidate tumor antigens in colorectal cancer revealed by the serological selection of a phage displayed cDNA expression library. J Immunol 169:2772-2780