Normal metabolism of apolipoprotein B100-containing lipoproteins despite qualitative abnormalities in type 1 diabetic men

Diabetologia

Volumn 48, Issue 7, 2005, Pages 1366-1372

  Duvillard, L ^a   Florentin, E ^a   Lalanne Mistrich, M L ^a   Petit, J M ^a   Baillot Rudoni, S ^a   Brun Pacaud, A ^a   Brun, J M ^a   Gambert, P ^a   Verges B ^a  

^a HÔPITAL DU BOCAGE   (France)

Author keywords

Apolipoprotein B100; IDL; Kinetic study; LDL; Stable isotope; Type 1 diabetes mellitus; VLDL

Indexed keywords

APOLIPOPROTEIN B100; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERMEDIATE DENSITY LIPOPROTEIN; LEUCINE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ARTICLE; ATHEROSCLEROSIS; BOLUS INJECTION; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; HIGH RISK PATIENT; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN INFUSION; KINETICS; MALE; PRIORITY JOURNAL; PROTEIN METABOLISM; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; APOLIPOPROTEIN B-100; APOLIPOPROTEINS B; BLOOD GLUCOSE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 1; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; KINETICS; LIPIDS; MALE; REFERENCE VALUES;

EID: 23944454564     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-1773-8     Document Type: Article

References (29)

1. Lopes-Virella MF, Wohltmann HJ, Loadholt CB, Buse MG (1981) Plasma lipids and lipoproteins in young insulin-dependent diabetic patients: relationship with control. Diabetologia 21:216-223
2. Perez A, Wagner AM, Carreras G et al (2000) Prevalence and phenotypic distribution of dyslipidemia in type 1 diabetes mellitus: effect of glycemic control. Arch Intern Med 160:2756-2762
3. Rivellesse A, Riccardi G, Romano G et al (1988) Presence of very low density lipoprotein compositional abnormalities in type 1 diabetic patients; effect of blood glucose optimization. Diabetologia 31:884-888
4. Pietri AO, Dunn FL, Raskin P (1983) The effect of continuous subcutaneous insulin infusion on very low density lipoprotein triglyceride metabolism in type 1 diabetes mellitus. Diabetes 32:75-81
5. Winocour PH, Durrington PN, Bhatnagar D, Ishola M, Arrol S, Mackness M (1992) Abnormalities of VLDL, IDL and LDL characterize insulin-dependent diabetes mellitus. Arterioscler Thromb 12:920-928
6. James RW, Pometta D (1990) Differences in lipoprotein subfraction composition and distribution between type 1 diabetic men and control subjects. Diabetes 39:1158-1164
7. Duvillard L, Pont F, Florentin E, Gambert P, Vergès B (2000) Significant improvement of apoB-containing lipoprotein metabolism by insulin treatment in NIDDM patients. Diabetologia 43:27-35
8. Duvillard L, Pont F, Florentin E, Gambert P, Vergès B (2000) Atherogenic abnormalities of apolipoprotein B-containing lipoprotein metabolism in NIDDM demonstrated by a stable isotope kinetic study. Eur J Clin Investig 30:685-694
9. Pont F, Duvillard L, Florentin E, Gambert P, Vergès B (2002) Early kinetic abnormalities of apoB-containing lipoproteins in insulin-resistant women with abdominal obesity. Arterioscler Thromb Vasc Biol 22:1726-1732
10. Klein RL, Zilversmit DB (1984) Direct determination of human and rabbit apolipoprotein B selectively precipitated with butanol-isopropyl ether. J Lipid Res 25:1380-1386
11. Cobelli C, Toffolo G, Foster DM (1992) Tracer-to-tracee ratio for analysis of stable isotope tracer data: link with radioactive formalism. Am J Physiol 262:E968-E975
12. Pont F, Duvillard L, Vergès B, Gambert P (1998) Development of compartmental models in stable isotope experiments: application to lipoprotein metabolism. Arterioscler Thromb Vasc Biol 18:853-860
13. Millar JS, Lichtenstein AH, Cuchel M et al (1995) Impact of age on the metabolism of VLDL, IDL, and LDL apolipoprotein B100 in men. J Lipid Res 36:1155-1167
14. Demant T, Packard CJ, Demmelmair H (1996) Sensitive methods to study human apolipoprotein B metabolism using stable isotope-labeled amino-acids. Am J Physiol 270:E1022-E1036
15. Ouguerram K, Chetiveaux M, Zair Y et al (2004) Apolipoprotein B metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9. Arterioscler Thromb Vasc Biol 24:1-6
16. Gibbons GF, Wiggings D, Brown AM, Hebbachi AM (2004) Synthesis and function of hepatic very-low-density lipoprotein. Biochem Soc Trans 32:59-64
17. Dixon JL, Ginsberg HN (1993) Regulation of apolipoprotein B-containing lipoproteins: information obtained from cultured cell liver. J Lipid Res 34:167-179
18. Brown AM, Gibbons GF (2001) Insulin inhibits the maturation phase of VLDL assembly via a phosphoinositide 3-kinase-mediated event. Arterioscler Thromb Vasc Biol 21:1656-1661
19. Christ ER, Carroll PV, Albany E et al (2001) Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus. Clin Endocrinol (Oxf) 55:777-787
20. Lewis GF, Uffelman KD, Szeto LW, Weller B, Steiner G (1995) Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans. J Clin Invest 95:158-166
21. Lewis GF, Uffelman KD, Szeto LW, Steiner G (1993) Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB production in normal weight and obese individuals. Diabetes 42:833-842
22. Bagdade JD, Dunn FL, Eckel RH, Ritter MC (1994) Intraperitoneal insulin therapy corrects abnormalities in cholesteryl ester transfer and lipoprotein lipase activities in insulin-dependent diabetes mellitus. Arterioscler Thromb 14:1933-1939
23. Caixas A, Perez A, Payes A et al (1998) Effects of a short acting insulin analog (Insulin Lispro) versus regular insulin on lipid metabolism in insulin-dependent diabetes mellitus. Metabolism 47:371-376
24. Ruotolo G, Parlavecchia M, Taskinen MR et al (1994) Normalization of lipoprotein composition by intraperitoneal insulin in IDDM. Role of increased hepatic lipase activity. Diabetes Care 17:6-12
25. Rosental SB, Schreier LE, Halperin H et al (1995) Low density lipoprotein rich in triglycerides and hepatic lipase activity in insulin-dependent diabetic patients [article in Spanish]. Medicina (B Aires) 55:317-323
26. Ritter MC, Bagdade JD (1994) Contribution of glycaemic control, endogenous lipoproteins and cholesteryl ester transfer protein to accelerated cholesteryl transfer in IDDM. Eur J Clin Invest 24:607-614
27. Viens L, Lagrost L (1997) Effect of lipid transfer activity and triglyceride hydrolysis on apolipoprotein B immunoreactivity in modified low density lipoproteins. J Lipid Res 38:1129-1138
28. Aviram M, Lund-Katz S, Phillips MC, Chait A (1988) The influence of the triglyceride content of low density lipoprotein on the interaction of apolipoprotein B-100 with cells. J Biol Chem 263:16842-16848
29. Panteghini M, Cimino A, Pagani F, Girelli A (1995) Nonenzymatic glycation of apolipoprotein B in patients with insulin-and noninsulin-dependent diabetes mellitus. Clin Biochem 28:587-592