Effect of lipid transfer activity and triglyceride hydrolysis on apolipoprotein B immunoreactivity in modified low density lipoproteins

Journal of Lipid Research

Volumn 38, Issue 6, 1997, Pages 1129-1138

  Viens, Laurence ^a   Lagrost, Laurent ^a  

^a INSERM   (France)

Author keywords

ApoB immunoreactivity; Cholesteryl ester transfer protein; Lipoprotein lipase

Indexed keywords

APOLIPOPROTEIN B; INTERMEDIATE DENSITY LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANTIBODY SPECIFICITY; ARTICLE; BINDING SITE; HUMAN; HUMAN CELL; HYDROLYSIS; IMMUNOREACTIVITY; LIPID COMPOSITION; LIPID TRANSPORT; LIPOPROTEIN METABOLISM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; TISSUE DISTRIBUTION;

EID: 0030923718     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Krauss, R. M., and D. J. Burke. 1982. Identification of multiple subclasses of plasma low density lipoproteins in normal humans. J. Lipid Res. 23: 97-104.
2. Gambert, P., C. Bouzerand-Gambert, A. Athias, M. Farnier, and C. Lallemant. 1990. Human low density lipoprotein subfractions separated by gradient gel electrophoresis: composition, distribution, and alterations induced by cholesteryl ester transfer protein. J. Lipid Res. 31: 1199-1210.
3. Campos, H., E. Blijlevens, J. R. McNamara, J. M. Ordovas, B. M. Posner, P. W. F. Wilson, W. P. Castelli, and E. J. Schaefer. 1992. LDL particle size distribution. Arterioscler. Thromb. 12: 1410-1419.
4. Chapman, M. J., P. M. Laplaud, G. Luc, P. Forgez, E. Bruckert, S. Coulinet, and D. Lagrange. 1988. Further resolution of the low density lipoprotein spectrum in normal human plasma: physicochemical characteristics of discrete subspecies separated by density gradient ultracentrifugation. J. Lipid Res. 29: 442-458.
5. Deckelbaum, R. J., S. Eisenberg, Y. Oschry, E. Butbul, I. Sharon, and T. Olivecrona. 1982. Reversible modification of human plasma low density lipoproteins toward triglyceride rich precursors. J. Biol. Chem. 257: 6509-6517.
6. Lagrost, L., P. Gambert, and C. Lallemant. 1994. Combined effects of lipid transfers and lipolysis on gradient gel patterns of human plasma LDL. Arterioscler. Thromb. 14: 1327-1336.
7. Austin, M. A., and R. M. Krauss. 1986. Genetic control of low density lipoprotein subclasses. Lancet. 2: 592-595.
8. Viens, L., A. Athias, G. Lizard, G. Simard, S. Gueldry, S. Braschi, P. Gambert, C. Lallemant, and L. Lagrost. 1996. Effect of lipid transfer activity and lipolysis on low density lipoprotein (LDL) oxidability: evidence for lipolysis-generated non-esterified fatty acids as inhibitors of LDL oxidation. J. Lipid Res. 37: 2179-2192.
9. Tikkanen, M. J., T. G. Cole, and G. Schonfeld. 1983. Differential reactivity of human low density lipoproteins with monoclonal antibodies. J. Lipid Res. 24: 1494-1499.
10. Harduin, P., A. Tailleux, J.-C. Fruchart, and C. Fievet. 1993. Modulation of the expression of human LDL apoB-100 epitopes by lipids and apolipoproteins. Arterioscler. Thromb. 13: 529-535.
11. Teng, B., A. Sniderman, R. M. Krauss, P. O. Kwiterovich, Jr., R. W. Milne, and Y. L. Marcel. 1985. Modulation of apolipoprotein B antigenic determinants in human low density lipoprotein subclasses. J. Biol. Chem. 260: 5067-5072.
12. Curtiss, L. K., and T. S. Edgington. 1982. Immunochemical heterogeneity of human plasma apolipoprotein B. I. Apolipoprotein B binding of mouse hybridoma antibodies. J. Biol. Chem. 257: 15213-15221.
13. Tsao, B. P., L. K. Curtiss, and T. S. Edgington. 1982. Immunochemical heterogeneity of human plasma apolipoprotein B. II. Expression of apolipoprotein B epilopes on native lipoproteins. J. Biol. Chem. 257: 15222-15228.
14. Salmon, S., S. Goldstein, D. Pastier, L. Theron, M. Berthelier, M. Ayrault-Jarrier, M. Dubarry, R. Rebourcet, and B. Pau. 1984. Monoclonal antibodies to low density lipoprotein used for the study of low and very low density lipoproteins, in "ELISA" and immunoprecipitation technics. Biochem. Biophys. Res. Commun. 125: 704-711.
15. Tikkanen, M. J., T. G. Cole, K-S. Hahm, E. S. Krul, and G. Schonfeld. 1984. Expression of apolipoprotein B epitopes in very low density lipoprotein subfractions Arteriosclerosis. 4: 138-146.
16. Marcel, Y. L., M. Hogue, P. K. Weech, J. Davignon, and R. W. Milne. 1988. Expression of apolipoprotein B epitopes in lipoproteins. Relationship to conformation and function. Arteriosclerosis. 8: 832-844.
17. Kleinman, Y., G. Schonfeld, D. Gavish, Y. Oschry, and S. Eisenberg. 1987. Hypolipidemic therapy modulates expression of apolipoprotein B epitopes on low density lipoproteins: studies in mild to moderate hypertriglyceridemic patients. J. Lipid Res. 28: 540-548.
18. Aviram, M., S. Lund-Katz, M. C. Phillips, and A. Chait. 1988. The influence of the triglyceride content of low density lipoprotein on the interaction of apolipoprotein B-100 with cells. J. Biol. Chem. 263: 16842-16848.
19. Kunitake, S. T., S. G. Young, G. C. Chen, C. R. Pullinger, S. Zhu, R. J. Pease, J. Scott, P. Hass, J. Schilling, and J. P. Kane. 1990. Conformation of apolipoprotein B-100 in the low density lipoproteins of Tangier disease. Identification of localized conformational response to triglyceride content. J. Biol. Chem. 265: 20739-20746.
20. Kinoshita, M., E. S. Krul, and G. Schonfeld. 1990. Modification of the core lipids of low density lipoproteins produces selective alterations in the expression of apoB-100 epitopes. J. Lipid Res. 31: 701-708.
21. McKeone, B. J., J. R. Patsch, and H. J. Pownall. 1993. Plasma triglycerides determine low density lipoprotein composition, physical properties, and cell-specific binding in cultured cells. J. Clin. Invest. 91: 1926-1933.
22. Galeano, N. F., R. Milne, Y. L. Marcel, M. T. Walsh, E. Levy, T-D. Ngu'yen, A. Gleeson, Y. Arad, L. Witte, M. Al-Haideri, S. C. Rumsey, and R. J. Deckelbaum. 1994. Apoprotein B structure and receptor recognition of triglyceride-rich low density lipoprotein is modified in small EDL but not in triglyceride-rich LDL of normal size. J. Biol. Chem. 269: 511-519.
23. Marcel, Y. L., M. Hogue, R. Theolis, Jr., and R. W. Milne. 1982. Mapping of antigenic determinants of human apolipoprotein B using monoclonal antibodies against low density lipoproteins. J. Biol. Chem. 257: 13165-13168.
24. Milne, R. W., R. Theolis, Jr., R. B. Verdery, and Y. L. Marcel. 1983. Characterization of monoclonal antibodies against human low density lipoprotein. Arteriosclerosis 3: 23-30.
25. Marcel, Y. L., T. L. Innerarity, C. Spilman, R. W. Mahley, A. A. Protter, and R. W. Milne. 1987. Mapping of human apolipoprotein B antigenic determinants. Arteriosclerosis. 7: 166-175.
26. Pease, R. J., R. W. Milne, W. K. Jessup, A. Law, P. Provost, J-C. Fruchart, R. T. Dean, Y. L. Marcel, and J. Scott. 1990. Use of bacterial expression cloning to localize the epitopes for a series of monoclonal antibodies against apolipoprotein B-100. J. Biol. Chem. 265: 553-568.
27. Milne, R., R. Theolis, Jr., R. Maurice, R. J. Pease, P. K. Weech, E. Rassart, J-C. Fruchart, J. Scott, and Y. Marcel. 1989. The use of monoclonal antibodies to localize the low density lipoprotein receptor binding domain of apolipoprotein B. J. Biol. Chem. 264: 19754-19760.
28. Gandjini, H., P. Gambert, A. Athias, and C. Lallemant. 1991. Resistance to LDL oxidative modifications of an N-terminal apolipoprotein B epitope. Atherosclerosis. 89: 83-93.
29. Smith, P. K., R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and D. C. Klenk. 1985. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150: 76-85.
30. Lagrost, L., H. Gandjini, A. Athias, V. Guyard-Dangremont, C. Lallemant, and P. Gambert. 1993. Influence of plasma cholesteryl ester transfer activity on the LDL and HDL distribution profiles in normolipidemic subjects. Arterioscler. Thromb. 13: 815-825.
31. Blanche, P. J., E. L. Gong, T. M. Forte, and A. V. Nichols. 1981. Characterization of human high density lipoproteins by gradient gel electrophoresis. Biochim. Biophys. Acta. 665: 408-419.
32. Campos, H., J. J. Genest, Jr., E. Blijlevens, J. R. McNamara, J. L. Jenner, J. M. Ordovas, P. W. F. Wilson, and E. J. Schaefer. 1992. Low density lipoprotein particle size and coronary artery disease. Arterioscler. Thromb. 12: 187-195.
33. Coresh, J., P. O. Kwiterovich, Jr., H. H. Smith, and P. S. Bachorik. 1993. Association of plasma triglyceride concentration and LDL particle diameter, density, and chemical composition with premature coronary artery disease in men and women. J. Lipid Res. 34: 1687-1697.
34. Jaakkola, O., T. Solakivi, V. V. Tertov, A. N. Orekhov, T. A. Miettinen, and T. Nikkari. 1993. Characteristics of low-density lipoprotein subfractions from patients with coronary artery disease. Coronary Artery Dis. 4: 379-385.
35. Austin, M. A., J. E. Hokanson, and J. D. Brunzell. 1994. Characterization of low density lipoprotein subclasses: methodological approaches and clinical relevance. Curr. Opin. Lipidol. 5: 395-403.
36. Rajman, I., S. Maxwell, R. Cramb, and M. Kendall. 1994. Particle size: the key to the atherogenic lipoprotein? Q. J. Med. 87: 709-720.
37. Marcel, Y. L., M. Hogue, P. K. Weech, and R. W. Milne. 1984. Characterization of antigenic determinants on human solubilized apolipoprotein B. Conformational requirements for lipids. J. Biol. Chem. 259: 6952-6957.
38. Patton, J. G., M. C. Alley, and S. J. T. Mao. 1982. Evaluation of monoclonal antibodies to human plasma low density lipoproteins. A requirement for lipids to maintain antigenic structure. J. Immunol. Methods. 55: 193-203.