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Volumn 46, Issue 8, 2005, Pages 847-860

Molecular target structures in oncology;Molekulare zielstrukturen in der onkologie

Author keywords

Hematological neoplasias; Molecular target structures; Monoclonal antibodies; Oncological therapy; Protein tyrosine kinases

Indexed keywords

ALEMTUZUMAB; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CETUXIMAB; EDRECOLOMAB; IBRITUMOMAB TIUXETAN; MYELOTARG; RITUXIMAB; TOSITUMOMAB I 131; TRASTUZUMAB;

EID: 23944444591     PISSN: 00209554     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00108-005-1463-0     Document Type: Review
Times cited : (4)

References (30)
  • 1
    • 1542313903 scopus 로고    scopus 로고
    • Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acqui-red drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells
    • Bagrintseva K, Schwab R, Kohl TM et al. (2004) Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acqui-red drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells. Blood 103: 2266-2275
    • (2004) Blood , vol.103 , pp. 2266-2275
    • Bagrintseva, K.1    Schwab, R.2    Kohl, T.M.3
  • 2
    • 0036817040 scopus 로고    scopus 로고
    • Epithelial growth factor receptor interacting agents
    • Baselga J, Albanell J (2002) Epithelial growth factor receptor interacting agents. Hematol Oncol Clin North Am 16: 1041-1063
    • (2002) Hematol Oncol Clin North Am , vol.16 , pp. 1041-1063
    • Baselga, J.1    Albanell, J.2
  • 3
    • 1842477418 scopus 로고    scopus 로고
    • Imatinib and beyond - The new CML study IV. A randomized controlled comparison of imatinib vs imatinib/interferon-alpha vs imatinib/low-dose AraC vs imatinib after interferon-alpha failure in newly diagnosed chronic phase chronic myeloid leukemia
    • Berger U, Engelich G, Reiter A, Hochhaus A, Hehlmann R (2004) Imatinib and beyond - the new CML study IV. A randomized controlled comparison of imatinib vs imatinib/interferon-alpha vs imatinib/low-dose AraC vs imatinib after interferon-alpha failure in newly diagnosed chronic phase chronic myeloid leukemia. Ann Hematol 83: 258-264
    • (2004) Ann Hematol , vol.83 , pp. 258-264
    • Berger, U.1    Engelich, G.2    Reiter, A.3    Hochhaus, A.4    Hehlmann, R.5
  • 4
    • 0036224208 scopus 로고    scopus 로고
    • CD33 as a target for selective ablation of acute myeloid leukemia
    • Bernstein ID (2002) CD33 as a target for selective ablation of acute myeloid leukemia. Clin Lymphoma 2: S9-11
    • (2002) Clin Lymphoma , vol.2
    • Bernstein, I.D.1
  • 5
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P, Hunter T (2001) Oncogenic kinase signalling. Nature 411: 355-365
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 6
    • 20844447330 scopus 로고    scopus 로고
    • Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations
    • Branford S, Rudzki Z, Parkinson I et al. (2004) Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations. Blood 104: 2926-2932
    • (2004) Blood , vol.104 , pp. 2926-2932
    • Branford, S.1    Rudzki, Z.2    Parkinson, I.3
  • 7
    • 0034900174 scopus 로고    scopus 로고
    • Approval summary: Gemtuzumab ozogamicin in relapsed acute myeloid leukemia
    • Brass PF, Beitz J, Chen G et al. (2001) Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res 7: 1490-1496
    • (2001) Clin Cancer Res , vol.7 , pp. 1490-1496
    • Brass, P.F.1    Beitz, J.2    Chen, G.3
  • 8
    • 12344325030 scopus 로고    scopus 로고
    • Monoclonal antibody treatment of malignant lymphoma
    • Buske C, Dreyling M, Unterhalt M, Hiddemann W (2004) [Monoclonal antibody treatment of malignant lymphoma]. Internist 45: 1370-1377
    • (2004) Internist , vol.45 , pp. 1370-1377
    • Buske, C.1    Dreyling, M.2    Unterhalt, M.3    Hiddemann, W.4
  • 9
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh MA, Vogel CL, Tripathy D et al. (1999) Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 17: 2639-2648
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 10
    • 0344987881 scopus 로고    scopus 로고
    • A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
    • Cools J, DeAngelo DJ, Gotlib J et al. (2003) A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 348: 1201-1214
    • (2003) N Engl J Med , vol.348 , pp. 1201-1214
    • Cools, J.1    DeAngelo, D.J.2    Gotlib, J.3
  • 12
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S et al. (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351: 337-345
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 13
    • 0037103424 scopus 로고    scopus 로고
    • Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
    • Demetri GD, von Mehren M, Blanke CD et al. (2002) Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 347: 472-480
    • (2002) N Engl J Med , vol.347 , pp. 472-480
    • Demetri, G.D.1    Von Mehren, M.2    Blanke, C.D.3
  • 14
    • 0035145435 scopus 로고    scopus 로고
    • All-trans retinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia
    • Fenaux P, Chomienne C, Degos L (2001) All-trans retinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia. Semin Hematol 38: 13-25
    • (2001) Semin Hematol , vol.38 , pp. 13-25
    • Fenaux, P.1    Chomienne, C.2    Degos, L.3
  • 15
    • 0012381722 scopus 로고    scopus 로고
    • Multiinstitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial)
    • Fukuoka M, Yano S, Giaccone G et al. (2003) Multiinstitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial). J Clin Oncol 21: 2237-2246
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 16
  • 17
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W et al. (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350: 2335-2342
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 19
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi S, Boggon TJ, Dayaram T et al. (2005) EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 352: 786-792
    • (2005) N Engl J Med , vol.352 , pp. 786-792
    • Kobayashi, S.1    Boggon, T.J.2    Dayaram, T.3
  • 20
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS et al. (2003) Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 290: 2149-2158
    • (2003) JAMA , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 21
    • 0033561797 scopus 로고    scopus 로고
    • Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
    • Melnick A, Licht JD (1999) Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 93: 3167-3215
    • (1999) Blood , vol.93 , pp. 3167-3215
    • Melnick, A.1    Licht, J.D.2
  • 22
    • 10744233716 scopus 로고    scopus 로고
    • Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
    • O'Brien SG, Guilhot F, Larson RA et al. (2003) Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 348: 994-1004
    • (2003) N Engl J Med , vol.348 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3
  • 23
    • 0033855713 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Structure, function, and clinical use
    • Osborne CK, Zhao H, Fuqua SA (2000) Selective estrogen receptor modulators: structure, function, and clinical use. J Clin Oncol 18: 3172-3186
    • (2000) J Clin Oncol , vol.18 , pp. 3172-3186
    • Osborne, C.K.1    Zhao, H.2    Fuqua, S.A.3
  • 24
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC et al. (2004) EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304: 1497-1500
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 25
    • 15744372810 scopus 로고    scopus 로고
    • KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
    • Epub 2005 Jan 25
    • Pao W, Wang TY, Riely GJ et al. (2005) KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2: e17. Epub 2005 Jan 25
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Wang, T.Y.2    Riely, G.J.3
  • 26
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S et al. (2001) Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344: 783-792
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 27
    • 0037441745 scopus 로고    scopus 로고
    • The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3
    • Spiekermann K, Dirschinger RJ, Schwab R et al. (2003) The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3. Blood 101: 1494-1504
    • (2003) Blood , vol.101 , pp. 1494-1504
    • Spiekermann, K.1    Dirschinger, R.J.2    Schwab, R.3
  • 28
    • 15244351004 scopus 로고    scopus 로고
    • Overview of monoclonal antibodies in cancer therapy: Present and promise
    • Stern M, Herrmann R (2005) Overview of monoclonal antibodies in cancer therapy: present and promise. Crit Rev Oncol Hematol 54: 11-29
    • (2005) Crit Rev Oncol Hematol , vol.54 , pp. 11-29
    • Stern, M.1    Herrmann, R.2
  • 29
    • 0141465061 scopus 로고    scopus 로고
    • The role of FLT3 in haematopoietic malignancies
    • Stirewalt DL, Radich JP (2003) The role of FLT3 in haematopoietic malignancies. Nat Rev Cancer 3: 650-665
    • (2003) Nat Rev Cancer , vol.3 , pp. 650-665
    • Stirewalt, D.L.1    Radich, J.P.2
  • 30
    • 19944427559 scopus 로고    scopus 로고
    • Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
    • Stone RM, DeAngelo DJ, Klimek V et al. (2005) Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood 105: 54-60
    • (2005) Blood , vol.105 , pp. 54-60
    • Stone, R.M.1    DeAngelo, D.J.2    Klimek, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.