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For a recent example, see: S. Quant, R.W. Wechselberger, M.A. Wolter, P. Wörmer, K.-H. Schell, J.W. Engels, C. Criesinger, and H. Schwalbe Tetrahedron Lett. 35 1994 6649 6652
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11
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33645333174
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note
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For the sake of clarity, we shall discuss the case of R = Me, only. The other benzyl or allyl groups might serve for various chemical manipulations.
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12
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33645374620
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note
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To a solution of 1,2-O-isopropylidene-3-O-methylxylofuranose (2.45 mmol) in an acetic anhydride (3.46 mL)/acetic acid (0.42 mL) was added 7 μL of fuming sulfuric acid. After 2 h the solution was cooled (0°C) and neutralized with a sodium carbonate solution. Usual extraction with ethyl acetate and purification gave 8 (R = Me) in 85% yield.
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