Ligament cells stretched on a microgrooved substrate increase intracellular calcium in response to a mechanical stimulus

Materials Research Society Symposium Proceedings

Volumn EXS, Issue 1, 2004, Pages 197-199

  Jones, Bertina F ^a,b   Banes, Albert J ^a,a,b,b,c,c   Wall, Michelle E ^b,c   Carroll, Lloyd ^a   Washburn, Scan ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTRACELLULAR CALCIUM; LIGAMENT CELLS; MECHANICAL STIMULUS; MEDIAL COLLATERAL LIGAMENT (MCL);

CALCIUM; DATA REDUCTION; DYES; ENZYMES; MATHEMATICAL MODELS; SILICONES; STRETCHING;

LIGAMENTS;

EID: 23844522826     PISSN: 02729172     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (5)

1. Woo, S., Livesay, G., Runco, T., Young, E. Structure and function of tendons and ligaments. Basic Orthopaedic Biomechanics. 1997
2. Hung, C., Allen, F., Pollack, S., Attia, E., Hannafin, J., Torzilli, P. Intracellular calcium response of ACL and MCL ligament fibroblasts to fluid-induced shear stress. Cell Signaling. 1997; 9(8):587-594.
3. Banes, A. J., Tsuzaki, M., Yamamato, J., Fischer, T., Brigman, B., Brown, T., Miller, L. Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals. Biochemistry and Cell Biology. 1995; 73(7):349.
4. Wang, J., Grood, E., Florer, J., Wenstrup, R. Alignment and proliferation of MC3T3-E1 osteoblasts in microgrooved silicone substrata subjected to cyclic stretching. Journal of Biomechanics. 2000; 33:729-735.
5. Elfervig, M., Graff, R., Lee, G., Kelley, S., Sood, A., Banes, A. ATP induces Ca2+ signaling in human chondrons cultured in three-dimensional agarose films. Osteoarthritis and Cartilage. 2001; 9:518-526.