Esophageal ATP synthase and keratinocyte growth factor gene expression changes after acid and bile-induced mucosal damage

Inflammation Research

Volumn 54, Issue 4, 2005, Pages 152-157

  Szentpali K ^a   Paszt, A ^a   Lazar G ^a   Szell M ^b   Kemeny L ^b   Dobozy, A ^c   Kaszaki, J ^a   Tiszlavicz, L ^b   Ivan L ^b   Boros, M ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

ATP synthase; Acute regurgitation; Experimental esophagitis; Gene expression; Keratinocyte growth factor; Mucosa

Indexed keywords

BILE ACID; HYDROCHLORIC ACID; KERATINOCYTE GROWTH FACTOR; KERATINOCYTE GROWTH FACTOR RECEPTOR; MESSENGER RNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ACIDITY; ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE EXACERBATION; DOG; DOWN REGULATION; ESOPHAGITIS; ESOPHAGUS BIOPSY; ESOPHAGUS INJURY; ESOPHAGUS MUCOSA; ESOPHAGUS MUSCLE; GENE EXPRESSION; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; TISSUE INJURY; TRANSCRIPTION INITIATION;

ANIMALS; ATP SYNTHETASE COMPLEXES; BILE ACIDS AND SALTS; DOGS; ESOPHAGEAL DISEASES; ESOPHAGUS; FIBROBLAST GROWTH FACTOR 1; GENE EXPRESSION REGULATION; HYDROCHLORIC ACID; MUCOUS MEMBRANE; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2;

EID: 23844503609     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-004-1336-3     Document Type: Article

References (19)

1. Wilmer A, Tack J, Frans E, Dits H, Vanderschueren S, Gevers A et al. Duodenogastroesophageal reflux and esophageal mucosal injury in mechanically ventilated patients. Gastroenterology 1999; 116: 1293-9.
2. Nehra D, Howell P, Williams CP, Pye JK, Beynon J. Toxic bile acids in gastro-oesophageal reflux disease: influence of gastric acidity. Gut 1999; 44: 598-602.
3. Szentpáli K, Kaszaki J, Tiszlavicz L, Lázár G, Balogh A, Boros M. Bile-induced adenosine triphosphate depletion and mucosal damage during reflux esophagitis. Scand J Gastroenterol 2001; 36: 459-66.
4. Martinez LO, Jacquet S, Esteve JP, Rolland C, Caberon E, Champagne E et al. Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis, Nature 2003; 421(6918): 75-9.
5. Bajaj-Elliott M, Breese E, Poulsom R, Fairclough PD, MacDonald TT. Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts. Am J Pathol. 1997; 151: 1469-76.
6. Geisinger KR, Cassidy KT, Nasdi R, Castell DO. The histologic development of acid-induced esophagitis in the cat. Mod Path 1990; 3: 619-24.
7. Ando J, Tsuboi H, Korenaga R, Takahashi K, Koshaki K, Isshaki M et al. Differential display and cloning of shear stress-responsive messenger RNAs in human endothelin cells. Biochem Biophys Res Commun 1996; 225: 347-51.
8. Kuo KW, Yang PY, Huang YS, Shieh DZ. Variations in gene expression and genomic stability of human hepatoma cells integrated with hepatitis B virus DNA. Biochem Mol Biol Int 1998; 44: 1133-40.
9. Ohsaka Y, Ohgiya S, Hoshino T, Ishizaki K. Mitochondrial genome-encoded ATPase subunit 6 + 8 mRNA increases in human hepatoblastoma cells in response to nonfatal cold stress. Cryobiology 2000; 40: 92-101.
10. Chen J, Gokhale M, Li Y, Trush MA, Yager JD. Enhanced levels of several mithochondrial mRNA transcripts and mitochondrial superoxide production during ethinyl estradiol-induced hepatocarcinogenesis and after estrogen treatment of HepG2 cells. Carcinogenesis 1998; 19: 2187-93.
11. Hayakawa M, Endo H, Hamamoto T, Kagawa Y. Acid stimulation induces a negative regulatory factor that affects alternative exon selection in vitro in human ATP synthase gamma-subunit pre-mRNA. Biochem Biophys Res Commun 1998; 251: 603-8.
12. Matsuda C, Endo H, Hirata H, Morosawa H, Nakanishi M, Kagawa Y. Tissue-specific isoforms of the bovine mitochondrial ATP synthase gamma-subunit. FEBS Lett. 1993; 325: 281-4.
13. Finch, PW, Rubin JS, Miki T, Ron D, Aaronson SA. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science 1989; 245: 752-55.
14. Housley RM, Morris CF, Boyle W, Ring B, Biltz R, Tarpley JE et al. Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract. J Clin Invest 1994; 94: 1764-77.
15. Kurtovic J, Segal I. Recent advances in biological therapy for inflammatory bowel disease. Trop Gastroenterol 2004; 25: 9-17.
16. Han DS, Li F, Holt L, Connolly K, Hubert M, Miceli R et al. Keratinocyte growth factor-2 (FGF-10) promotes healing of experimental small intestinal ulceration in rats. Am J Physiol 2000; 279: G1011-22.
17. Finch PW, Cheng AL. Analysis of the cellular basis of keratinocyte growth factor overexpression in inflammatory bowel disease. Gut 1999; 45: 848-55.
18. Estivariz CF, Gu LH, Scully S, Eli A, Jonas CR, Farrell CL et al. Regulation of keratinocyte growth factor (KGF) and KGF receptor mRNAs by nutrient intake and KGF administration in rat intestine. Dig Dis Sci 2000; 45: 736-43.
19. Ishiwata T, Naito Z, Lu JP, Kawahara K, Fujii T, Kawamoto T et al. Differential distribution of fibroblast growth factor (FGF)-7 and FGF-10 in L-arginine-induced acute pancreatitis. Exp Mol Pathol 2002; 73: 181-90.