The immune status of Kupffer cells profoundly influences their responses to infectious Plasmodium berghei sporozoites

European Journal of Immunology

Volumn 35, Issue 8, 2005, Pages 2335-2346

  Steers, Nick ^a   Schwenk, Robert ^a   Bacon, David J ^b   Berenzon, Dmitri ^a   Williams, Jackie ^a   Krzych, Urszula ^a  

^a WRAIR   (United States)

^b NMRC   (United States)

Author keywords

Antigen presenting cells; Cytokines; Kupffer cells; MHC; P. berghei

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IMMUNE STATUS; KUPFFER CELL; MALARIA; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPOROZOITE; UPREGULATION;

ANIMALS; ANTIGEN PRESENTATION; FEMALE; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-4; KUPFFER CELLS; LIVER; MALARIA; MICE; MICE, INBRED C57BL; PLASMODIUM BERGHEI; RNA, MESSENGER; SPOROZOITES;

EID: 23844500084     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200425680     Document Type: Article

References (33)

1. Rickman, K. H., Beaudoin, R. L., Cassels, J. S. and Sell, D. W., Use of attenuated sporozoites in the immunization of human volunteers against falciparum, malaria. Bull. WHO 1979. 57: 261-265.
2. Nussenzweig, R. S., Vanderberg, J., Most, H. and Orton, C., Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature 1967. 216: 160-162.
3. Hoffman, S. L., Goh, L. M., Luke, T. C., Schneider, I., Le, T. P., Doolan, D. L., Sacci, J. et al., Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. J. Infect. Dis. 2002. 185: 1155-1164.
4. Scheller, L. F. and Azad, A. F., Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites. Proc. Natl. Acad. Sci. USA 1995. 92: 4066-4068.
5. Nardin, E. H. and Nussenzweig, R. S., T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stages. Annu. Rev. Immunol. 1993. 11: 687-727.
6. + T lymphocytes is required for protective immunity against Plasmodium berghei. J. Immunol. 1996. 156: 3374-3381.
7. + T cells. J. Immunol. 2003. 171: 2024-2034.
8. Frevert, U., Sneaking in through the back entrance: the biology of malaria liver stages. Trends Parasitol. 2004. 20: 417-424.
9. Ishino, T., Yano, K., Chinzei, Y. and Yuda, M., Cell-passage activity is required for the malarial parasite to cross the liver sinusoidal cell layer. PLoS Biol. 2004. 2: E4.
10. Frevert, U., Galinski, M. R., Hugel, F. U., Allon, N., Schreier, H., Smulevitch, S., Shakibaei, M. and Clavijo, P., Malaria circumsporozoite protein inhibits protein synthesis in mammalian cells. EMBO J. 1998. 17: 3816-3826.
11. Meis, J. F., Verhave, J. P., Jap, P. H. and Meuwissen, J. H., An ultrastructural study on the role of Kupffer cells in the process of infection by Plasmodium berghei sporozoites in rats. Parasitology 1983. 86 (Pt 2): 231-242.
12. Vreden, S. G., Sauerwein, R. W., Verhave, J. P., Van Rooijen, N., Meuwissen, J. H. and Van Den Broek, M. F., Kupffer cell elimination enhances development of liver schizonts of Plasmodium berghei in rats. Infect. Immun. 1993. 61: 1936-1939.
13. Vreden, S. G., van den Broek, M. F., Oettinger, M. C., Verhave, J. P., Meuwissen, J. H. and Sauerwein, R. W., Cytokines inhibit the development of liver schizonts of the malaria parasite Plasmodium berghei In vivo. Eur. J. Immunol. 1992. 22: 2271-2275.
14. Krzych, U., Schwenk, R., Guebre-Xabier, M., Sun, P., Palmer, D., White, K. and Chalom, I., The role of intrahepatic lymphocytes in mediating protective immunity induced by attenuated Plasmodium berghei sporozoites. Immunol. Rev. 2000. 174: 123-134.
15. Knolle, P. A. and Limmer, A., Neighborhood politics: the immunoregulatory function of organ-resident liver endothelial cells. Trends Immunol. 2001. 22: 432-437.
16. Iwai, Y., Terawaki, S., Ikegawa, M., Okazaki, T. and Honjo, T., PD-1 inhibits antiviral immunity at the effector phase in the liver. J. Exp. Med. 2003. 198: 39-50.
17. Guebre-Xabier, M., Schwenk, R. and Krzych, U., Memory phenotype CD8 T cells persist in livers of mice protected against malaria by immunization with attenuated Plasmodium berghei sporozoites. Eur. J. Immunol. 1999. 29: 3978-3986.
18. Grewal, I. S. and Flavell, R. A., The role of CD40 ligand in costimulation and T-cell activation. Immunol. Rev. 1996. 153: 85-106.
19. Carreno, B. M. and Collins, M., The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 2002. 20: 29-53.
20. Knolle, P. A., Uhrig, A., Protzer, U., Trippler, M., Duchmann, R., Meyer zum Buschenfelde, K. H. and Gerken, G., Interleukin-10 expression is autoregulated at the transcriptional level in human and murine Kupffer cells. Hepatology 1998. 27: 93-99.
21. + T cells in the Plasmodium yoelii model. J. Immunol. 1999. 163: 884-892.
22. Launois, P., Swihart, K. G., Milon, G. and Louis, J. A., Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness. J. Immunol. 1997. 158: 3317-3324.
23. Rogoff, T. M. and Lipsky, P. E., Antigen presentation by isolated guinea pig Kupffer cells. J. Immunol. 1980. 124: 1740-1744.
24. Grant, E. P. and Rock, K. L., MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and In vivo. J. Immunol. 1992. 148: 13-18.
25. Reis e Sousa, C. and Germain, R. N., Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J. Exp. Med. 1995. 182: 841-851.
26. Khan, S., van den Broek, M., Schwarz, K., de Giuli, R., Diener, P. A. and Groettrup, M., Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver. J. Immunol. 2001. 167: 6859-6868.
27. Piedrafita, D., Proudfoot, L., Nikolaev, A. V., Xu, D., Sands, W., Feng, G. J., Thomas, E. et al., Regulation of macrophage IL-12 synthesis by Leishmania phosphoglycans. Eur. J. Immunol. 1999. 29: 235-244.
28. Pradel, G., Garapaty, S. and Frevert, U., Kupffer and stellate cell proteoglycans mediate malaria sporozoite targeting to the liver. Comp. Hepatol. 2004. 3 Suppl 1: S47.
29. Zhu, J. D., Waters, A. P., Appiah, A., McCutchan, T. F., Lal, A. A. and Hollingdale, M. R., Stage-specific ribosomal RNA expression switches during sporozoite invasion of hepatocytes. J. Biol. Chem. 1990. 265: 12740-12744.
30. Mota, M. M., Pradel, G., Vanderberg, J. P., Hafalla, J. C., Frevert, U., Nussenzweig, R. S., Nussenzweig, V. and Rodriguez, A., Migration of Plasmodium sporozoites through cells before infection. Science 2001. 291: 141-144.
31. Plebanski, M., Flanagan, K. L., Lee, E. A., Reece, W. H., Hart, K., Gelder, C., Gillespie, G. et al., Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum. Immunity 1999. 10: 651-660.
32. Kurtis, J. D., Hollingdale, M. R., Luty, A. J., Lanar, D. E., Krzych, U. and Duffy, P. E., Pre-erythrocytic immunity to Plasmodium falciparum: the case for an LSA-1 vaccine. Trends Parasitol. 2001. 17: 219-223.
33. Krzych, U., Guebre-Xabier, M. and Schwenk, R., Malaria and the liver: tolerance and immunity to attenuated Plasmodia sporozoites. In Crispe I. N., (Ed) T Lymphocytes in the Liver: Immunobiology, Pathology and Host Defense. Wiley-Liss, New York: 1999, pp 163-196.